Results 81 to 90 of about 605,748 (301)

MiRNA-related metastasis in oral cancer: moving and shaking

Cancer Cell International, 2023
Across the world, oral cancer is a prevalent tumor. Over the years, both its mortality and incidence have grown. Oral cancer metastasis is a complex process involving cell invasion, migration, proliferation, and egress from cancer tissue either by ...
Meghdad Eslami, Saba Khazeni, Xaniar Mohammadi Khanaghah, Mohammad Hossein Asadi, Mohamad Amin Ansari, Javad Hayati Garjan, Mohammad Hassan Lotfalizadeh, Mobina Bayat, Mohammad Taghizadieh, Seyed Pouya Taghavi, Michael R Hamblin, Javid Sadri Nahand   +11 more
doaj   +1 more source

Long non-coding RNA SENCR is a positive regulator of ETV2 [PDF]

, 2017
Department of Biological SciencesAlthough long non-coding RNAs (lncRNAs) have emerged as novel regulator of cell fate and gene expression, the regulation of vascular specific transcription factor by lncRNA in generation of induced endothelial cells ...
Jeong, Yujin
core  

Viral RNAs are unusually compact. [PDF]

, 2014
A majority of viruses are composed of long single-stranded genomic RNA molecules encapsulated by protein shells with diameters of just a few tens of nanometers.
Ben-Shaul, Avinoam, Egecioglu, Defne E, Gelbart, William M, Gopal, Ajaykumar, Knobler, Charles M, Rao, Ayala LN, Yoffe, Aron M   +6 more
core   +3 more sources

Viruses hijack a long non-coding RNA [PDF]

Nature, 2017
Manipulation of host-cell metabolism is an essential aspect of viral replication cycles. Viral co-option of a cellular long non-protein-coding RNA has now been found to be a key step in this process. Manipulation of host-cell metabolism is an essential aspect of viral replication cycles. Viral co-option of a cellular long non-protein-coding RNA has now
Nicholas S, Heaton, Bryan R, Cullen
openaire   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Revealing potential long non-coding RNA biomarkers in lung adenocarcinoma using long non-coding RNA-mediated competitive endogenous RNA network

Brazilian Journal of Medical and Biological Research
In our study, we aimed to reveal potential long non-coding RNAs (lncRNA) biomarkers in lung adenocarcinoma (LAD) using lncRNA-mediated competing endogenous RNAs (ceRNAs) network (LMCN).
T-G. Zhu, X. Xiao, Q. Wei, M. Yue, L-X. Zhang   +4 more
doaj   +1 more source

The complex transcriptional landscape of the anucleate human platelet. [PDF]

, 2013
BACKGROUND: Human blood platelets are essential to maintaining normal hemostasis, and platelet dysfunction often causes bleeding or thrombosis. Estimates of genome-wide platelet RNA expression using microarrays have provided insights to the platelet ...
Bray, Paul F, Chen, Huang-Wen, Delgrosso, Kathleen, Edelstein, Leonard, Ertel, Adam, Fortina, Paolo, Jing, Yi, Kupper, Joan, Loher, Phillipe, Londin, Eric R, McKenzie, Steven E, Nagalla, Srikanth, Rigoutsos, Isidore   +12 more
core   +1 more source

Predicting long non-coding RNAs using RNA sequencing

Methods, 2013
The advent of next-generation sequencing, and in particular RNA-sequencing (RNA-seq), technologies has expanded our knowledge of the transcriptional capacity of human and other animal, genomes. In particular, recent RNA-seq studies have revealed that transcription is widespread across the mammalian genome, resulting in a large increase in the number of
Ilott, N, Ponting, C
openaire   +2 more sources

PLncDB: plant long non-coding RNA database [PDF]

Bioinformatics, 2013
Abstract Summary: Plant long non-coding RNA database (PLncDB) attempts to provide the following functions related to long non-coding RNAs (lncRNAs): (i) Genomic information for a large number of lncRNAs collected from various resources; (ii) an online genome browser for plant lncRNAs based on a platform similar to that of the UCSC Genome
Jingjing, Jin, Jun, Liu, Huan, Wang, Limsoon, Wong, Nam-Hai, Chua   +4 more
openaire   +2 more sources

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source