Results 1 to 10 of about 39,616 (286)

QT Adaptation and Intrinsic QT Variability in Congenital Long QT Syndrome [PDF]

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2015
Background Increased variability of QT interval (QTV) has been linked to arrhythmias in animal experiments and multiple clinical situations. Congenital long QT syndrome (LQTS), a pure repolarization disease, may provide important information on the ...
Srikanth Seethala, Prabhpreet Singh, Vladimir Shusterman, Margareth Ribe, Kristina H. Haugaa, Jan Němec   +5 more
doaj   +2 more sources

Congenital long QT syndrome [PDF]

Orphanet Journal of Rare Diseases, 2008
Congenital long QT syndrome (LQTS) is a hereditary cardiac disease characterized by a prolongation of the QT interval at basal ECG and by a high risk of life-threatening arrhythmias. Disease prevalence is estimated at close to 1 in 2,500 live births. The
Celano Giuseppe, Crotti Lia, Dagradi Federica, Schwartz Peter J   +3 more
doaj   +6 more sources

GENETIC ASPECTS OF CONGENITAL LONG QT SYNDROME

Рациональная фармакотерапия в кардиологии, 2015
The main symptoms and clinical types of long QT syndrome are described. Molecular genetic diagnostics and updated approaches to the management of patients with long QT syndrome arepresented.
A. A. Chernova, S. Yu. Nikulina, A. V. Gul'bis   +2 more
doaj   +4 more sources

Congenital Long QT Syndrome

JACC: Clinical Electrophysiology, 2022
Congenital long QT syndrome (LQTS) encompasses a group of heritable conditions that are associated with cardiac repolarization dysfunction. Since its initial description in 1957, our understanding of LQTS has increased dramatically. The prevalence of LQTS is estimated to be ∼1:2,000, with a slight female predominance.
Andrew D. Krahn, Zachary Laksman, Raymond W. Sy, Pieter G. Postema, Michael J. Ackerman, Arthur A.M. Wilde, Hui‐Chen Han   +6 more
openalex   +4 more sources

The Long QT Syndrome

Indian Pacing and Electrophysiology Journal, 2002
The Long QT syndrome (LQTS) can be inherited or acquired and is of particular interest and concern at present. Patients with LQTS are predisposed to the ventricular tachyarrhythmia torsade de pointes (TdP) which causes syncope and sudden death. Inherited
G. Michael Vincent
doaj   +2 more sources

Case Report: Two cases of recurrent syncope caused by KCNH2 gene mutation in congenital long QT syndrome [PDF]

Frontiers in Cardiovascular Medicine
This study presents two cases of congenital long QT syndrome caused by KCNH2 gene mutations. It highlights the critical role of genetic testing in its diagnosis and underscores the importance of early detection and personalized treatment strategies to ...
Aihua Xing, Lifang Liu, Lifang Liu, Wenjuan Pei, Wenjuan Pei, Xiaoyan Zhang   +5 more
doaj   +2 more sources

Long QT syndrome [PDF]

Canadian Medical Association Journal, 2011
In a First Nation community located northeast of Haida Gwaii in British Columbia, a 38-year-old woman required resuscitation from an apparent cardiac arrest that had occurred while she was coaching at a competitive sports event. She had a history of syncope and palpitations.
Heather, Jackson, Lee-Anna, Huisman, Shubhayan, Sanatani, Laura T, Arbour   +3 more
openaire   +4 more sources

The long QT syndrome [PDF]

Europace, 2001
The Long QT syndrome (LQTS) is an inherited arrhythmogenic disease occurring in the structurally normal heart that may cause sudden death and that usually manifests in children and teen-agers (1). The prevalence of this disorder is still undefined, however it is estimated to be between 1:10000–1:5000.
Priori, SG, Bloise, R, Crotti, L
openaire   +3 more sources

In Vitro Drug Screening Using iPSC-Derived Cardiomyocytes of a Long QT-Syndrome Patient Carrying KCNQ1 & TRPM4 Dual Mutation: An Experimental Personalized Treatment

Cells, 2022
Congenital long QT syndrome is a type of inherited cardiovascular disorder characterized by prolonged QT interval. Patient often suffer from syncopal episodes, electrocardiographic abnormalities and life-threatening arrhythmia.
Feifei Wang, Yafan Han, Wanyue Sang, Lu Wang, Xiaoyan Liang, Liang Wang, Qiang Xing, Yankai Guo, Jianghua Zhang, Ling Zhang, Tuerhong Zukela, Jiasuoer Xiaokereti, Yanmei Lu, Xianhui Zhou, Baopeng Tang, Yaodong Li   +15 more
doaj   +1 more source

The long-QT syndrome [PDF]

Trends in Cardiovascular Medicine, 1992
The familial long-QT syndrome (LQTS) is an infrequently occurring disorder in which affected family members have QT prolongation on the ECG, often associated with recurrent syncope and fatal ventricular arrhythmias. Autosomal recessive and autosomal dominant modes of inheritance were suggested by the pattern of occurrence of this disorder in the first ...
Arthur J. Moss, Jennifer L. Robinson
openaire   +1 more source