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Congenital long QT syndrome [PDF]

open access: yesOrphanet Journal of Rare Diseases, 2008
Congenital long QT syndrome (LQTS) is a hereditary cardiac disease characterized by a prolongation of the QT interval at basal ECG and by a high risk of life-threatening arrhythmias. Disease prevalence is estimated at close to 1 in 2,500 live births. The
Celano Giuseppe   +3 more
doaj   +11 more sources

Mechanisms, Risk Factors, and Management of Acquired Long QT Syndrome: A Comprehensive Review [PDF]

open access: yesThe Scientific World Journal, 2012
Long QT syndrome is characterized by prolongation of the corrected QT (QTc) interval on the surface electrocardiogram and is associated with precipitation of torsade de pointes (TdP), a polymorphic ventricular tachycardia that may cause sudden death ...
Eleftherios M. Kallergis   +4 more
doaj   +4 more sources

The role of M cells and the long QT syndrome in cardiac arrhythmias: simulation studies of reentrant excitations using a detailed electrophysiological model [PDF]

open access: yesChaos Vol 14 pages 172-182 (2004), 2004
In this numerical study, we investigate the role of intrinsic heterogeneities of cardiac tissue due to M cells in the generation and maintenance of reentrant excitations using the detailed Luo-Rudy dynamic model. This model has been extended to include a
Cherry E. M.   +3 more
core   +2 more sources

Pueraria mirifica, an estrogenic tropical herb, unveiled the severity of Type 1 LQTS caused by KCNQ1‐T587M [PDF]

open access: yesJournal of Arrhythmia, 2021
After taking an estrogen-containing supplement derived from a tropical plant Pueraria mirifica, a 24-year-old woman presented marked QT prolongation and repetitive torsade de pointes.
Asami Kashiwa   +7 more
doaj   +2 more sources

Clarithromycin-Induced Long QT Syndrome: A Case Report [PDF]

open access: yesCase Reports in Medicine, 2012
Long QT syndrome develops for a number of reasons. The number of non-antiarrhythmic drugs reported to induce QT interval prolongation with or without torsade de pointes continues to increase.
Mecnun Cetin   +4 more
doaj   +3 more sources

Torsades de pointes during laparoscopic adrenalectomy of a pheochromocytoma: a case report [PDF]

open access: yesJournal of Medical Case Reports, 2011
Introduction Torsades de pointes is a rare but potentially lethal arrhythmia. The amount of literature available on Torsades de pointes occurring in patients with pheochromocytoma is limited, and we found no literature describing this dysrhythmia in a ...
Wiesfeld Ans CP   +4 more
doaj   +5 more sources

Long QT syndrome - causes and risk factors [PDF]

open access: yesJournal of Education, Health and Sport, 2018
Sudden cardiac death is a major public health challenge, which can be caused by genetic or acquired structural or electrophysiological abnormalities. These abnormalities include channelopathies such as long QT, short QT and Brugada syndromes.
Erwin Ciechański   +3 more
doaj   +6 more sources

Congenital Short QT Syndrome [PDF]

open access: yesIndian Pacing and Electrophysiology Journal, 2004
Long QT intervals in the ECG have long been associated with sudden cardiac death. The congenital long QT syndrome was first described in individuals with structurally normal hearts in 1957.1 Little was known about the significance of a short QT ...
Charles Antzelevitch, Johnson Francis
doaj   +2 more sources

Long QT syndrome provoked by induction of general anesthesia -A case report- [PDF]

open access: yesKorean Journal of Anesthesiology, 2010
Long QT syndrome (LQTS) is an arrhythmogenic cardiovascular disorder resulting from mutations in cardiac ion channels. LQTS is characterized by prolonged ventricular repolarization and frequently manifests itself as QT interval prolongation on the ...
Hyung Tae Kim   +5 more
doaj   +4 more sources

In Vitro Drug Screening Using iPSC-Derived Cardiomyocytes of a Long QT-Syndrome Patient Carrying KCNQ1 & TRPM4 Dual Mutation: An Experimental Personalized Treatment

open access: yesCells, 2022
Congenital long QT syndrome is a type of inherited cardiovascular disorder characterized by prolonged QT interval. Patient often suffer from syncopal episodes, electrocardiographic abnormalities and life-threatening arrhythmia.
Feifei Wang   +15 more
doaj   +1 more source

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