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Long-QT-Syndrom

Praxis, 2010
#### Case scenario A 19 year old female student consulted her general practitioner about two recent episodes of syncope, both of which occurred while playing hockey. Her team mates reported that she collapsed suddenly with little warning, recovering rapidly within 30 seconds without confusion.
D J, Abrams, M A, Perkin, J R, Skinner
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Long QT Syndrome

New England Journal of Medicine
Key Points Long QT Syndrome Long QT syndrome is a leading cause of sudden death in young persons, with a prevalence exceeding 1 in 2000. It is characterized by prolongation of the QT interval, aberrant T-wave morphologic features, and the propensity toward life-threatening arrhythmias triggered mostly by adrenergic activation.
Michele, Bibas   +2 more
  +7 more sources

Congenital Long QT Syndrome

JACC: Clinical Electrophysiology, 2022
Congenital long QT syndrome (LQTS) encompasses a group of heritable conditions that are associated with cardiac repolarization dysfunction. Since its initial description in 1957, our understanding of LQTS has increased dramatically. The prevalence of LQTS is estimated to be ∼1:2,000, with a slight female predominance.
Andrew D, Krahn   +6 more
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Long QT Syndrome

American Journal of Critical Care, 2006
Some researchers claim that babies should be routinely tested for long QT syndrome (LQTS) by electrocardiogram (ECG) at around 3 weeks of age because it would be cost-effective and save lives. Bottom line. The ECG is neither sensitive nor specific to hereditary LQTS and can be hard to interpret in newborns.
Michele M, Pelter, Mary G, Carey
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Long QT Syndrome and Short QT Syndrome

Progress in Cardiovascular Diseases, 2008
The long QT syndrome (LQTS) is a genetic disorder characterized by prolongation of the QT interval in the electrocardiogram (ECG) and a propensity to torsades de pointes ventricular tachycardia frequently leading to syncope, cardiac arrest, or sudden death usually in young otherwise healthy individuals.
Wojciech, Zareba, Iwona, Cygankiewicz
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The long QT syndrome

Current Problems in Cardiology, 1980
The still inadequate but increasing awareness of the existence of the idiopathic long QT syndrome (LQTS) has provided ample evidence that, as suggested by many, this disease is far from being rare. This notion, coupled with the unusual pathophysiological characteristics and with the high degree of lethality in untreated patients, explains why the LQTS ...
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Long QT syndrome in children

Journal of Electrocardiology, 2001
The long QT syndrome (LQTS) is a congenital disorder characterized by a prolongation of the QT interval on electrocardiogram and a propensity to ventricular tachyarrhythmias, which may lead to cardiac events defined as syncope, cardiac arrest, or sudden death. Children are very frequently affected by LQTS accounting for about 50% of probands and 40% to
W, Zareba, A J, Moss
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LONG QT SYNDROME

Cardiology Clinics, 2000
In conclusion, much has been learned in the past several years regarding the molecular biology of LQTS, and this information has been directly applicable to the clinical care of patients with this syndrome. The knowledge also has been of considerable importance for understanding the molecular basis of arrhythmias in general and is providing insights ...
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Famotidine and long QT syndrome

The American Journal of Cardiology, 2004
Numerous drugs have been implicated in causing a prolonged QT interval and Torsades de pointes. However, the association of famotidine and acquired long QT syndrome has rarely been reported. We report 2 cases of famotidine-associated acquired long QT syndrome.
Ken W, Lee   +4 more
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Long QT syndrome and anaesthesia

European Journal of Anaesthesiology, 2002
The long QT syndrome is a disorder of myocardial electrical conduction that leaves the heart vulnerable to the ventricular tachydysrhythmia torsade de pointes. Clinically, this results in syncope or sudden death. The long QT syndrome may be congenital, if caused by abnormal myocardial potassium or sodium ion channels, or acquired, if due to drugs ...
N A, Wisely, E A, Shipton
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