Results 101 to 110 of about 423,334 (338)
Thorough QT/QTc (TQT) study [PDF]
, 2021 With a number of drugs entering the market, cardiac safety remains a cause of major concern for the regulatory authorities, before approval. The incidence of drug induced arrhythmia with non-cardiovascular drugs is low, however the result is fatal, hence
Balasundaram, Lakshmi +2 more
core +2 more sources
ESC Heart Failure, EarlyView.Abstract Aims The Tpeak‐Tend interval on electrocardiogram may be a predictor of worse outcomes in Takotsubo syndrome (TTS), but the mechanisms have not been fully determined. This study aimed to investigate the relationships between the corrected Tpeak‐Tend (cTp‐e) interval and coronary microvascular‐dysfunction (CMD) assessed by the angiography ...
Kyohei Onishi +6 more
wiley +1 more source
Circulation Research, 2017 Rationale: Calmodulinopathies comprise a new category of potentially life-threatening genetic arrhythmia syndromes capable of producing severe long-QT syndrome (LQTS) with mutations involving CALM1, CALM2, or CALM3.
Worawan B Limpitikul +12 more
semanticscholar +1 more source
Long QT syndrome and anaesthesia [PDF]
British Journal of Anaesthesia, 2003 Long QT syndrome (LQTS) is an arrhythmogenic cardiovascular disorder resulting from mutations in cardiac ion channels. LQTS is characterized by prolonged ventricular repolarization and frequently manifests itself as QT interval prolongation on the electrocardiogram (ECG). The age at presentation varies from in utero to adulthood.
Peter D. Booker +2 more
openaire +2 more sources
Epilepsia Open, EarlyView.Abstract The Ankyrin 2 (ANK2) gene encodes the ankyrin‐B protein (ANKB), which is involved in the organization and stability of membrane ion channels, transporters, and receptors in cardiomyocytes and neurons. Variants in ANK2 genes are initially reported in long QT syndrome and autism.
Po‐Hsi Lin +5 more
wiley +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021 Background Long QT has been associated with ventricular dysrhythmias, cardiovascular disease (CVD) mortality, and sudden cardiac death. However, no studies to date have investigated the dynamics of within‐person QT change over time in relation to risk of
Neha Mantri +8 more
doaj +1 more source
The genetics underlying acquired long QT syndrome: impact for genetic screening.
European Heart Journal, 2016 AIMS Acquired long QT syndrome (aLQTS) exhibits QT prolongation and Torsades de Pointes ventricular tachycardia triggered by drugs, hypokalaemia, or bradycardia. Sometimes, QTc remains prolonged despite elimination of triggers, suggesting the presence of
H. Itoh +21 more
semanticscholar +1 more source
Early Detection of Post-COVID-19 Fatigue Syndrome Using Deep Learning Models [PDF]
arXiv, 2023 The research titled "Early Detection of Post-COVID-19 Fatigue Syndrome using Deep Learning Models" addresses a pressing concern arising from the COVID-19 pandemic. Post-COVID-19 Fatigue Syndrome (PCFS) has become a significant health issue affecting individuals who have recovered from COVID-19 infection. This study harnesses a robust dataset comprising
arxiv
Exome sequencing helped the fine diagnosis of two siblings afflicted with atypical Timothy syndrome (TS2) [PDF]
, 2014 BACKGROUND: Long-QT syndrome (LQTS) causes a prolongation of the QT-interval in the ECG leading to life threatening tachyarrhythmia and ventricular fibrillation.
Berger, F. +7 more
core +1 more source
Clinical pharmacology and therapy, 2016 Drug‐induced long QT syndrome has resulted in many drugs being withdrawn from the market. At the same time, the current regulatory paradigm for screening new drugs causing long QT syndrome is preventing drugs from reaching the market, sometimes ...
L. Johannesen +18 more
semanticscholar +1 more source