Results 171 to 180 of about 169,795 (221)

Clinical progress note: Management of the hospitalized patient who uses methamphetamine

Journal of Hospital Medicine, Volume 20, Issue 4, Page 380-384, April 2025.
Alexander A. Logan, Lawrence A. Haber, Marlene Martín   +2 more
wiley   +1 more source

Advances and Challenges in Quizartinib‐Based FLT3 Inhibition for Acute Myeloid Leukemia: Mechanisms of Resistance and Prospective Combination Therapies

European Journal of Haematology, Volume 114, Issue 4, Page 584-595, April 2025.
ABSTRACT FLT3 mutations are among the most common genetic alterations in acute myeloid leukemia (AML) and are associated with poor prognosis. Significant advancements have been made in developing FLT3 inhibitors (FLT3Is), such as quizartinib, which have improved treatment outcomes in both newly diagnosed and relapsed/refractory AML.
Antonella Bruzzese, Enrica Antonia Martino, Caterina Labanca, Francesco Mendicino, Eugenio Lucia, Virginia Olivito, Teresa Rossi, Antonino Neri, Fortunato Morabito, Ernesto Vigna, Massimo Gentile   +10 more
wiley   +1 more source

Homozygosity for a HERG potassium channel mutation causes a severe form of long QT syndrome: identification of an apparent founder mutation in the Finns

, 2000
Kirsi Piippo, Päivi Laitinen, Heikki Swan, Lauri Toivonen, Matti Viitasalo, Michael Pasternack, Kristian Paavonen, Hugh Chapman, Kenneth T. Wann, Eeva Hirvelä, Antti Sajantila, Kimmo Kontula   +11 more
openalex   +1 more source

Correlation of genetic etiology with response to β-adrenergic blockade among symptomatic patients with familial long-QT syndrome [PDF]

, 2001
Toshio Itoh, Kenjiro Kikuchi, Yasuhisa Odagawa, S. Takata, K. Yano, Saori Okada, Noriyuki Haneda, Satoshi Ogawa, Osami Nakano, Yoshihiro Kawahara, Hideaki Kasai, T. Nakayama, Takashi Fukutomi, Harumizu Sakurada, Akihiko Shimizu, Y Yazaki, Ryohei Nagai, Yushi Nakamura, Toshihiro Tanaka   +18 more
openalex   +1 more source

The Role of Infarct Border Zone Remodelling in Ventricular Arrhythmias: Bridging Basic Research and Clinical Applications

Journal of Cellular and Molecular Medicine, Volume 29, Issue 7, April 2025.
ABSTRACT Patients who experience post‐myocardial infarction (MI) and present with a left ventricular ejection fraction of less than 35% are classified as being at high risk for sudden cardiac death due to ventricular arrhythmias (VAs). The expansion of scar tissue and the extension of the infarct border zone (IBZ) following MI play critical roles in ...
Jin Ma, Qiuxiong Chen, Dongqun Lin, Shiyu Ma   +3 more
wiley   +1 more source

Screening for drug-induced (acquired) long QT syndrome: is it time to apply new methods? [PDF]

, 2001
Paolo Emilio Puddu
openalex   +1 more source

Characterisation of sleep apneas and respiratory circuitry in mice lacking CDKL5

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary CDKL5 deficiency disorder is a rare genetic disease caused by mutations in the CDKL5 gene. Central apneas during wakefulness have been reported in patients with CDKL5 deficiency disorder. Studies on CDKL5‐knockout mice, a CDKL5 deficiency disorder model, reported sleep apneas, but it is still unclear whether these events are central (central ...
Gabriele Matteoli, Sara Alvente, Stefano Bastianini, Chiara Berteotti, Elisabetta Ciani, Elenia Cinelli, Viviana Lo Martire, Giorgio Medici, Tommaso Mello, Elena Miglioranza, Alessandro Silvani, Donatella Mutolo, Giovanna Zoccoli   +12 more
wiley   +1 more source

Cycle Length‐Associated Modulation of the Regional Dispersion of Ventricular Repolarization in a Canine Model of Long QT Syndrome [PDF]

, 2001
Masaomi Chinushi, Edward B. Caref, Mark Restivo, GIANDOMENICO NOLL, Yoshifusa Aizawa, Nabil El‐Sherif   +5 more
openalex   +1 more source

Role of DNA testing for diagnosis, management, and genetic screening in long QT syndrome, hypertrophic cardiomyopathy, and Marfan syndrome [PDF]

, 2001
G. Michael Vincent
openalex   +1 more source

Phase 2 Early Afterdepolarization as a Trigger of Polymorphic Ventricular Tachycardia in Acquired Long-QT Syndrome [PDF]

, 2001
Gan‐Xin Yan, Ying Wu, Tengxian Liu, Jixin Wang, Roger A. Marinchak, Peter R. Kowey   +5 more
openalex   +1 more source