Results 41 to 50 of about 72,190 (244)

Prevalence of Long QT Syndrome in Children with Congenital Sensory-Neural Deafness

Journal of Ardabil University of Medical Sciences, 2021
Background & objectives: Long QT syndrome (LQTS), congenital or acquired disorder, is characterized by a prolonged QT interval associated with syncope attacks and sudden death.
Ahmad Jamei Khosroshahi, Mahmoud Samadi, Shamsi Ghaffari, Akbar Molaei, Fatemeh Chakari   +4 more
doaj  

Comparative Characteristics of Beta-Blockers in Patients with Congenital Long QT Syndrome

Рациональная фармакотерапия в кардиологии, 2021
Congenital long QT syndrome is a pathology that requires special attention and knowledge about the safety and effectiveness of various medications.
A. Yu. Proshlyakov, P. Sh. Chomakhidze, N. A. Novikova   +2 more
doaj   +1 more source

QT Adaptation and Intrinsic QT Variability in Congenital Long QT Syndrome

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2015
Background Increased variability of QT interval (QTV) has been linked to arrhythmias in animal experiments and multiple clinical situations. Congenital long QT syndrome (LQTS), a pure repolarization disease, may provide important information on the ...
Srikanth Seethala, Prabhpreet Singh, Vladimir Shusterman, Margareth Ribe, Kristina H. Haugaa, Jan Němec   +5 more
doaj   +1 more source

[Congenital long QT syndrome].

Archivos peruanos de cardiologia y cirugia cardiovascular, 2021
El síndrome QT largo (SQTL) congénito representa un grupo de enfermedades cardiacas de origen genético, caracterizado por la prolongación del intervalo QT y una onda T anormal en el electrocardiograma (ECG). Pueden tener una expresión dominante o recesiva, esta última asociada con sordera neurosensorial.
Melgar Quicaño, Luis, Chipa Ccasani, Fredy   +1 more
openaire   +2 more sources

Congenital long QT syndrome in children [PDF]

Medicinski Podmladak, 2016
Long QT syndrome (LQTS) is a cardiac repolarization disorder characterized by prolonged QT interval on the electrocardiogram (ECG) and increased propensity to ventricular tachyarrhythmias and cardiac events.
Cerović Ivana, Košutić Jovan
doaj   +1 more source

CaMKII-dependent regulation of cardiac Na(+) homeostasis. [PDF]

, 2014
Na(+) homeostasis is a key regulator of cardiac excitation and contraction. The cardiac voltage-gated Na(+) channel, NaV1.5, critically controls cell excitability, and altered channel gating has been implicated in both inherited and acquired arrhythmias.
Grandi, Eleonora, Herren, Anthony W
core   +2 more sources

Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism

Advanced Science, EarlyView.
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying, Hangping Fan, Yunhe Wang, Ruhong Jiang, Dongsheng Cai, Hui Cheng, Hao Wang, Chenyang Jiang, Ping Liang   +8 more
wiley   +1 more source

Selective acquired long QT syndrome (saLQTS) upon risperidone treatment

BMC Psychiatry, 2012
Background Numerous structurally unrelated drugs, including antipsychotics, can prolong QT interval and trigger the acquired long QT syndrome (aLQTS). All of them are thought to act at the level of KCNH2, a subunit of the potassium channel.
Lazarczyk Maciej, Bhuiyan Zahir A, Perrin Nicolas, Giannakopoulos Panteleimon   +3 more
doaj   +1 more source

Restricting excessive cardiac action potential and QT prolongation: a vital role for IKs in human ventricular muscle [PDF]

, 2005
Background - Although pharmacological block of the slow, delayed rectifier potassium current (I-Ks) by chromanol 293B, L-735,821, or HMR-1556 produces little effect on action potential duration (APD) in isolated rabbit and dog ventricular myocytes, the ...
Biliczki, Péter, Bitay, Miklós, Bogáts, Gábor, Jost, Norbert, Lathrop, David A., Lengyel, Csaba Attila, Nagy, Zsolt, Papp, Gyula, Takács, János, Varró, András, Virág, László   +10 more
core   +1 more source

Vascularized Cardiac Tissue Engineering: From Advances in Biofabrication to Translational Applications

Advanced Science, EarlyView.
This review presents a process‐oriented framework for vascularized cardiac tissue engineering, highlighting how the coordinated design of cells, biomaterials, and biofabrication strategies enables the functional development or vascularized myocardium for disease modelling and drug discovery.
Yang Liu, Zijie Zhang, Hongbin Li, Lino Prados‐Martin, Huanhong Li, Feng Cheng, Xia Tu, Khoon S. Lim, Wanlu Li, Mian Wang   +9 more
wiley   +1 more source