Results 71 to 80 of about 7,350,665 (262)

Long QT syndrome. New electrocardiographic characteristics.

, 1990
The long QT syndrome is electrocardiographically characterized by a prolonged QT interval and by several other, more subtle, ST-T-U wave abnormalities, most of which have not been quantified.
W J Hall, E Locati, J Benhorin, A J Moss, M Alberti, M Merri, L Cui   +6 more
core   +1 more source

A new form of long QT syndrome associated with syndactyly [PDF]

, 1995
Objectives. The purpose of this study was to characterize a possible association between long QT syndrome and syndactyly.Background. Long QT syndrome causes syncope and sudden death from ventricular arrhythmias.
Marks, Melinda L, Melinda L Marks, Mark Keating, Sandra L Whisler, Whisler, Sandra L, Clericuzio, Carol, Carol Clericuzio, Keating, Mark   +7 more
core   +1 more source

Characterization of a variant in the KCNH2 gene in an Ecuadorian patient with long QT syndrome: A case report

Medwave
Long QT syndrome is a rare cardiac channelopathy characterized by prolonged QT intervals and altered T wave morphology. The etiology of long QT syndrome is multifactorial, including environmental and genetic factors.
Santiago Cadena-Ullauri, Patricia Guevara-Ramírez, Rafael Tamayo-Trujillo, Rita Ibarra-Castillo, José Luis Laso-Bayas, Elius Paz-Cruz, Viviana A. Ruiz-Pozo, Daniel Simancas-Racines, Ana Karina Zambrano   +8 more
doaj   +1 more source

Accelerating virtual patient generation with a Bayesian optimization and machine learning surrogate model

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 486-494, March 2025.
Abstract The pharmaceutical industry has increasingly adopted model‐informed drug discovery and development (MID3) to enhance productivity in drug discovery and development. Quantitative systems pharmacology (QSP), which integrates drug action mechanisms and disease complexities to predict clinical endpoints and biomarkers is central to MID3.
Hiroaki Iwata, Ryuta Saito
wiley   +1 more source

Integrative Approaches in Cardiovascular Disease: The Role of Nutraceuticals in Heart Failure, Atrial Fibrillation, and Related Conditions

Phytotherapy Research, EarlyView.
Schematic representation of the shared pathophysiological mechanisms underlying heart failure (HF) and atrial fibrillation (AF), including inflammation, oxidative stress, endothelial dysfunction, and fibrosis. The figure highlights the clinical and mechanistic convergence of conventional pharmacological therapies and selected nutraceuticals in ...
Laura Beatrice Mattioli, Ivan Corazza, Roberta Budriesi, Luca Camarda, Maria Carelli, Alberto Spadotto, Igor Diemberger   +6 more
wiley   +1 more source

Le QT long acquis [Acquired long QT syndrome].

, 2013
The long QT syndrome may be acquired or genetically determined. The syndrome is characterized by a prolonged QT interval and is associated with an increased risk of cardiac arrhythmia such as a torsade de pointe and death.
Schlaepfer, J., Zürcher, J.P., Waeber, G., Pasquier, M.   +3 more
core   +1 more source

Long QT Syndrome

JACC: Case Reports, 2023
Domenico Corrado, MD, PhD, Domenico Trovato, MD, Alessandro Zorzi, MD, PhD   +2 more
doaj   +1 more source

Long QT Syndrome in Adults

Journal of the American College of Cardiology, 2007
The aims of this study were: 1) to evaluate risk factors influencing the clinical course of mutation-confirmed adult patients with long QT syndrome (LQTS), 2) to study life-threatening cardiac events as a specific end point in adults, and 3) to examine the protective effect of beta-blocker therapy on cardiac events in adult LQTS patients with known ...
Sauer, Andrew J., Moss, Arthur J., McNitt, Scott, Peterson, Derick R., Zareba, Wojciech, Robinson, Jennifer L., Qi, Ming, Goldenberg, Ilan, Hobbs, Jenny B., Ackerman, Michael J., Benhorin, Jesaia, Hall, W. Jackson, Kaufman, Elizabeth S., Locati, Emanuela H., Napolitano, Carlo, Priori, Silvia G., Schwartz, Peter J., Towbin, Jeffrey A., Vincent, G. Michael, Zhang, Li   +19 more
openaire   +3 more sources

Halting the Progression of Acute Kidney Injury: A Tubular‐Inspired Reusable Detoxifier Against Protein‐Bound Uremic Toxins and Oxidative Stress

SusMat, EarlyView.
This graphical ToC illustrates a tubular‐inspired detoxifier (SDCMs–DS) that halts acute kidney injury progression. Inspired by proximal tubular epithelial cells (PTECs), the biomimetic design combines dissociation‐adsorption clearance of protein‐bound uremic toxins (PBUTs) with antioxidant protection. During hemoperfusion, danshensu (DS) released from
Yilin Wang, Jiahao Liang, Xijing Yang, Xin Song, Yujie Xiao, Xiran Zhou, Hongyu Xiang, Shujing Wang, Shengjun Cheng, Xianda Liu, Yu Chen, Weifeng Zhao, Changsheng Zhao   +12 more
wiley   +1 more source

Modulating effects of age and gender on the clinical course of long QT syndrome by genotype

, 2003
Modulating effects of age and gender on the clinical course of long QT syndrome by ...
Vincent GM, Zhang L, Lehmann MH, Timothy K, International Long QT Syndrome Registry, PRIORI, SILVIA GIULIANA, Hall WJ, SCHWARTZ, PETER, Moss AJ, Peterson DR, Benhorin J, Locati EH, Robinson JL, Zareba W, Towbin JA, Andrews ML, Medina A, Napolitano C   +17 more
core