Results 41 to 50 of about 41,523 (260)

Multicellular String-Like Structure Formation by Salmonella Typhimurium Depends on Cellulose Production: Roles of Diguanylate Cyclases, YedQ and YfiN

open access: yesFrontiers in Microbiology, 2020
Bacteria face diverse stresses in the environment and, sometimes, respond by forming multi-cellular structures, e.g., biofilms. Here, we report a novel macroscopic and multi-cellular structure formed by Salmonella Typhimurium, which resembles small ...
Alan Varghese   +3 more
doaj   +1 more source

Gravitating spinning strings in AdS3

open access: yesJournal of High Energy Physics, 2022
In the AdS/CFT correspondence, single trace operators of large-N gauge theories at large spin J can be described by classical spinning strings, giving a geometric and classical description of their spectrum at strong coupling.
Henry Maxfield, Zhencheng Wang
doaj   +1 more source

Extrusion deformation estimation method of oil and gas string basedon AIC-RBF

open access: yesYou-qi chuyun, 2021
It is difficult to measure the deformation of oil and gas strings affected by the ground movement for a long time. In order to solve this problem, an inversion algorithm for extrusion deformation estimation of oil and gas strings based on pulsed eddy ...
Xuanyong ZHOU   +5 more
doaj   +1 more source

"How Long is a Piece of String": [PDF]

open access: yesProceedings of the 2017 Workshop on Cyber-Physical Systems Security and PrivaCy, 2017
The numbers and severity of global cyber security attacks on Industrial Control Systems have increased over recent years. However, there are also significant efforts to improve defensive capabilities. While comprehensive reviews of risk assessment efforts exist, little detail is currently available on how they are being applied by security ...
Green, Benjamin   +3 more
openaire   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

When strings surprise

open access: yesJournal of High Energy Physics
We argue that on-shell excitations with large negative energies are created rapidly when the string coupling increases with time. This does not indicate an inconsistency in string theory since the negative energy on-shell excitation is always entangled ...
Nissan Itzhaki, Uri Peleg
doaj   +1 more source

Stabilizing homogeneous black strings in AdS

open access: yesJournal of High Energy Physics, 2020
It is known that homogenous black strings in flat spacetime are unstable under long wavelength perturbations. Recently, by including scalar fields that depend on the extended coordinates only, homogenous black strings have been constructed in the ...
Adolfo Cisterna   +2 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Superstrings on AdS3 at k = 1

open access: yesJournal of High Energy Physics, 2018
We study superstring theory in three dimensional Anti-de Sitter spacetime with NS-NS flux, focusing on the case where the radius of curvature is equal to the string length.
G. Giribet   +4 more
doaj   +1 more source

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