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The Long-Term Outcome of Maudsley Depressives
British Journal of Psychiatry, 1988Eighty-nine consecutive admissions with primary depressive illness were prospectively ascertained and diagnosed in 1965–66 by R. E. Kendell, who also allocated each a position on a neurotic-psychotic continuum on the basis of previous discriminant function analysis. In 1983–84, 94% of the survivors were personally interviewed by a psychiatrist blind to
A S, Lee, R M, Murray
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The long-term stability of depressive subtypes
American Journal of Psychiatry, 1994This study used the concept of diagnostic stability to examine the validity of three subtypes of major depression.Patients with major depressive disorder (N = 424) were assigned baseline diagnoses according to structured interviews and the Research Diagnostic Criteria.
W, Coryell +5 more
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Depression in the long-term course of schizophrenia
European Archives of Psychiatry and Clinical Neuroscience, 2005Depressive symptoms are quantitatively and qualitatively among the most important characteristics of schizophrenia. The following contribution reports on the prevalence of depression in 107 patients of the ABC schizophrenia study over 12 years after first hospital admission, looks into a preponderance of depression at certain stages of the illness and ...
Wolfram, an der Heiden +4 more
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Long-Term Potentiation and Long-Term Depression
2018Abstract Synaptic connections in the brain can change their strength in response to patterned activity. This ability of synapses is defined as synaptic plasticity. Long lasting forms of synaptic plasticity, long-term potentiation (LTP), and long-term depression (LTD), are thought to mediate the storage of information about stimuli or ...
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Long-Term Potentiation and Long-Term Depression
Abstract Synaptic plasticity, the ability of chemical synapses to strengthen or weaken, has long been postulated to be a mechanistic basis of memory. Long-term potentiation (LTP), one form of synaptic plasticity, is defined as a persistent increase in the strength of synaptic transmission, whereas long-term depression (LTD) is the ...openaire +1 more source
Long-term Depression Overcomes Long-term Facilitation
Science Signaling, 2002In the short-term, a single neuron receiving multiple excitatory and inhibitory inputs at spatially distinct locales will sum all of them into the decision of whether or not to fire a nerve impulse. Guan et al. investigated the mechanisms whereby neurons integrate facilitatory and inhibitory inputs leading to long ...
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Long-Term Potentiation, Long-Term Depression, and Learning
1998Publisher Summary Almost everyone agrees that information is acquired, stored, and retrieved by the brain. All brains consist of individual cellular elements. Most neurons have the same parts: a dendritic tree, cell body, axon, and synaptic boutons.
Joe L. Martinez +2 more
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Annales medico-psychologiques, 1990
Our practice, in a unit of treatment of dysthymic state being confronted with problems of relapses and recurrences, we have questioned the therapeutic strategies in the long run and their possible assessments. After recalling conceptual and methodological reference about relapses, recurrences and therapeutic assessment, we propose the methods and first
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Our practice, in a unit of treatment of dysthymic state being confronted with problems of relapses and recurrences, we have questioned the therapeutic strategies in the long run and their possible assessments. After recalling conceptual and methodological reference about relapses, recurrences and therapeutic assessment, we propose the methods and first
openaire +1 more source
Long-term potentiation and long-term depression
2006Zafir I. Bashir, Peter V. Massey
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