Deriving and comparing healthy longevity distributions by gender and health prevalence measures: a statistical moments and maximum entropy approach. [PDF]
Popul Health MetrCosulich R, di Lego V, Zarulli V.
europepmc +1 more source
Postsynaptic Complexin Mediates Constitutive Exocytosis of Nicotinic Acetylcholine Receptor
Advanced Science, EarlyView.Beyond its established presynaptic role, complexin is identified as a postsynaptic regulator of neurotransmitter receptor trafficking. By promoting constitutive and activity‐dependent exocytosis of nicotinic acetylcholine receptors, complexin controls spontaneous synaptic signaling at the C.
Ya Wang +4 more
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Advanced Science, EarlyView.ABSTRACT Intestinal ischemia/reperfusion (I/R) injury presents a biphasic pathology: an acute oxidative‐inflammatory phase leading to organ failure, and a recovery phase marked by mucosal dysfunction and bacterial translocation. The developed MPB@TA‐Cu‐Ma nanocomposite functions as a dual‐phase therapeutic platform with significant efficacy. It rapidly
Chenghao Qiu +15 more
wiley +1 more source
Natural killer cells: gatekeepers of healthy aging in longevity medicine. [PDF]
Inflamm RegenYang JY, Tu DT, Liao JC, Lee OK.
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Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro
Advanced Science, EarlyView.The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel +15 more
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Effects of Different Sugar Types on Longevity, Fecundity, and Nutrient Metabolism in <i>Sclerodermus guani</i> Xiao <i>et</i> Wu (Hymenoptera: Bethylidae). [PDF]
InsectsHu ZJ, Qiu SQ, Min B, Yao XJ, Jia MY.
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Advanced Science, EarlyView.This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li +15 more
wiley +1 more source
Phenotypic Plasticity in <i>Arabidopsis thaliana</i> Is Fitness-Neutral, and Costs Are Lacking Across Experimental Environments. [PDF]
Ecol EvolShamsid-Deen ML, Whitney KD.
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Scalable Manufacturing of Roll‐to‐Roll Slot‐Die Coated Perovskite Solar Cells
Advanced Science, EarlyView.Roll‐to‐roll (R2R) slot‐die coating is emerging as a scalable pathway for perovskite solar cells. This mini‐review summarizes advances in ink design, drying control, and electrode integration that enable high‐efficiency flexible devices and modules. Challenges in throughput, stability, and sustainable processing are outlined, guiding the translation of
Farshad Jafarzadeh +5 more
wiley +1 more source
Time to focus on solutions for social disconnection
The Lancet. Healthy LongevityThe Lancet Healthy Longevity
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