Results 71 to 80 of about 25,301,115 (309)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The analysis of multivariate longitudinal data: A review [PDF]
Longitudinal experiments often involve multiple outcomes measured repeatedly within a set of study participants. While many questions can be answered by modeling the various outcomes separately, some questions can only be answered in a joint analysis of all of them.
VERBEKE, Geert +3 more
openaire +4 more sources
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Across the social sciences, there is widespread agreement that quantitative longitudinal research designs offer analysts powerful scientific data resources. However, a large number of texts on social survey analysis are written from a statistical, rather
Gayle, V.J.
core +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
A Longitudinal Analysis of Computing in the Home [PDF]
This paper reports on the use of personal computers in the home. Analyses were conducted on US Census Current Population Survey data on computer usage from 1984 to 1997. Findings are presented with regard to the diffusion of ownership and usage pattems of personal computers in the home. Implications on social impact of home computing are discussed.
Alladi Venkatesh +2 more
openaire +2 more sources
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
longitudinal analysis, meta-analysis, multilevel analysis,
Lensvelt-Mulders, G.J.L.M. +5 more
core +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Orphans and schooling in Africa: A longitudinal analysis [PDF]
Abstract AIDS deaths could have a major impact on economic development by affecting the human capital accumulation of the next generation. We estimate the impact of parent death on primary school participation using an unusual five-year panel data set of over 20,000 Kenyan children.
Evans, David, Miguel, Edward A.
openaire +4 more sources

