Results 81 to 90 of about 1,373,523 (316)

Longitudinal functional principal component analysis [PDF]

open access: yesElectronic Journal of Statistics, 2010
We introduce models for the analysis of functional data observed at multiple time points. The dynamic behavior of functional data is decomposed into a time-dependent population average, baseline (or static) subject-specific variability, longitudinal (or dynamic) subject-specific variability, subject-visit-specific variability and measurement error. The
Greven, Sonja   +3 more
openaire   +3 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

社會網絡與心理幸福因果關聯的方向性之探討:臺東師院追蹤調查資料的貫時性分析 The Study on the Directionality of Causal Relationship between Social Network and Psychological Well-Being: A Longitudinal Analysis of Panel Survey’s Data from National Taitung Teachers College

open access: yes臺灣教育社會學研究, 2006
過去眾多的實證研究結果顯示:社會網絡對心理幸福有很重要的正面影響。由於過去這方面的國內研究較少使用長期追蹤調查資料,以及做適當的統計分析,因此大部分的研究無法釐清這兩個變項因果關聯之方向性。本研究目的在於探討「以上兩個變項之因果方向性到底為何」,這當可為教育社會學開拓一個新的研究議題。本研究使用了1,047位國立臺東師院學生的追蹤調查資料納入統計分析,並對相關干擾變項的影響做進一步控制。貫時性因果分析顯示:心理幸福對社會網絡有正面影響,社會網絡則對心理幸福沒有影響,即得到「心理幸福為因,社會網絡為果 ...
林俊瑩 Chunn-Ying Lin   +1 more
doaj  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Acculturation attitudes and social adjustment in British South Asian children: A longitudinal study. [PDF]

open access: yes, 2013
A 1-year longitudinal study with three testing points was conducted with 215 British Asian children aged 5 to 11 years to test hypotheses from Berry’s acculturation framework.
Anick Landau (16053803)   +26 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Multivariate spatial statistical analysis of longitudinal data in perennial crops [PDF]

open access: yes, 2006
The advantages of using spatial analysis in annual crop experiments are well documented. There is much less evidence for perennial crops. For the sequence of measurements in perennial crops, apparently, there are no published articles in spatial analysis
De Resende, M. D. V.   +2 more
core  

Statistico-genetic considerations in longitudinal data analysis

open access: yes, 2008
The methodology of longitudinal data analysis (LDA) has been discussed with particular reference to applications in studies on nutrition and animal breeding.
Narain, Prem
core   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

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