Results 61 to 70 of about 1,373,523 (316)

Sensitivity Analysis in Nonrandomized Longitudinal Mediation Analysis [PDF]

open access: yesFrontiers in Psychology, 2021
Mediation analysis relies on an untestable assumption of the no omitted confounders, which posits that an omitted variable that confounds the relationships between the antecedent, mediator, and outcome variables cannot exist. One common model in alcohol addiction studies is a nonrandomized latent growth curve mediation model (LGCMM), where the ...
openaire   +3 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Convergence of Romanian accounting regulations with IFRS. A longitudinal analysis

open access: yesAudit Financiar, 2016
In this paper we analyse the evolution in the level of convergence of the Romanian accounting regulations with IFRS in the last decade. We focus our study on the accounting topics covered by IAS16, IAS17, IAS 41 and SIC15.
Ioana PĂLĂRIE, Nadia ALBU
doaj   +1 more source

Changing Attitudes Towards Gender Equality in Switzerland (2000–2017): Period, Cohort and Life-Course Effects

open access: yesSwiss Journal of Sociology, 2020
This paper investigates trends in Swiss women’s and men’s gender attitudes in the period 2000–2017 using the Swiss Household Panel data. Based on pooled OLS and fixed-effects models, we establish the following for women and men: (1) over this time period,
Bornatici Christina   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Imputing income in the Longitudinal Study of Australian Children [PDF]

open access: yes, 2015
This paper explains why imputing missing income data is of benefit to Longitudinal Study of Australian Children and shows how two techniques have been used in combination to impute this income data.
Galina Daraganova   +2 more
core  

The analysis of multivariate longitudinal data: A review [PDF]

open access: yesStatistical Methods in Medical Research, 2012
Longitudinal experiments often involve multiple outcomes measured repeatedly within a set of study participants. While many questions can be answered by modeling the various outcomes separately, some questions can only be answered in a joint analysis of all of them.
VERBEKE, Geert   +3 more
openaire   +4 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Sensitivity analysis within multiple imputation framework using delta-adjustment: Application to Longitudinal Study of Australian Children

open access: yes, 2018
Multiple imputation (MI) is a powerful statistical method for handling missing data. Standard implementations of MI are valid under the unverifiable assumption of missing at random (MAR), which is often implausible in practice.
Lee, Katherine J.   +2 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

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