Results 61 to 70 of about 2,996,820 (336)

Recommendations for Incorporating Postsecondary and Workforce Data into Statewide Longitudinal Data Systems [PDF]

, 2010
Outlines the need for data systems to assess educational transitions, completions, and labor market outcomes of adult students and workers in postsecondary, adult education, and skill development programs in order to strengthen policies and ...
Andrew Reamer, Brandon Roberts, Evelyn Ganzglass, Rachel Unruh, Whitney Smith   +4 more
core  

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

The relationship between fundamental motor skills and physical fitness in preschoolers: a short-term longitudinal study

Frontiers in Psychology, 2023
PurposePhysical fitness and fundamental motor skills are two important aspects for the healthy development of preschoolers. Despite the growing interest in clarifying their relationship, the scarcity of longitudinal studies prevents us from understanding
Jiebo Chen, Jiebo Chen, Wenjing Song, Xing Zhao, Hu Lou, Dongmei Luo   +5 more
doaj   +1 more source

Evolution of the longitudinal structure function at small x

, 2014
We derive an approximation approach to evolution of the longitudinal structure function, by using a Laplace-transform method. We solve the master equation and derive the longitudinal structure function as a function of the initial condition $F_{L}(x,Q^{2}
Boroun, G. R.
core   +1 more source

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

Molecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban, Shivakumar Keerthikumar, Ashlee Clark, Hong Wang, Belinda Phipson, Andrew Bakshi, Andrew Ryan, Heather Thorne, Renea A. Taylor, Mitchell G. Lawrence, Gail P. Risbridger, Roxanne Toivanen, David L. Goode   +12 more
wiley   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Health data issues in Africa: time for digitization, standardization and harmonization

Nature Communications
This commentary discusses health data challenges in Africa, focusing on digitization, standardization, and harmonization as key solutions. It highlights how addressing these foundational issues can enable AI and data science to transform healthcare ...
Abdoelnaser Degoot, Ismaël Koné, Shakuntala Baichoo, Mercy Ngungu, Nzisa Liku, Judit Kumuthini, Joyce Nakatumba-Nabende, Foutse Khomh, Bubacarr Bah   +8 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

q2-longitudinal: Longitudinal and Paired-Sample Analyses of Microbiome Data [PDF]

mSystems, 2018
Longitudinal sampling provides valuable information about temporal trends and subject/population heterogeneity. We describe q2-longitudinal, a software plugin for longitudinal analysis of microbiome data sets in QIIME 2. The availability of longitudinal statistics and visualizations in the QIIME 2 framework will make the analysis of longitudinal data ...
Nicholas A. Bokulich, Matthew R. Dillon, Yilong Zhang, Jai Ram Rideout, Evan Bolyen, Huilin Li, Paul S. Albert, J. Gregory Caporaso   +7 more
openaire   +5 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source