Results 61 to 70 of about 1,626,021 (272)

Predictive Distributions and the Transition from Sparse to Dense Functional Data [PDF]

open access: yesarXiv, 2021
A representation of Gaussian distributed sparsely sampled longitudinal data in terms of predictive distributions for their functional principal component scores (FPCs) maps available data for each subject to a multivariate Gaussian predictive distribution.
arxiv  

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

A framework to construct a longitudinal DW-MRI infant atlas based on mixed effects modeling of dODF coefficients [PDF]

open access: yesarXiv, 2020
Building of atlases plays a crucial role in the analysis of brain images. In scenarios where early growth, aging or disease trajectories are of key importance, longitudinal atlases become necessary as references, most often created from cross-sectional data.
arxiv  

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

brolgar: An R package to BRowse Over Longitudinal Data Graphically and Analytically in R [PDF]

open access: yesarXiv, 2020
Longitudinal (panel) data provide the opportunity to examine temporal patterns of individuals, because measurements are collected on the same person at different, and often irregular, time points. The data is typically visualised using a "spaghetti plot", where a line plot is drawn for each individual.
arxiv  

Unemployment and Subjective Well-being Among the Youth: Evidence from a Longitudinal Study in Poland

open access: yesStudies of Transition States and Societies, 2018
The main aim of this paper is to investigate the impact of becoming unemployed on the well-being of young people. Particularly, we examine to what extent this relationship is moderated by the local unemployment rate.
Magdalena Rokicka   +2 more
doaj  

The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise

open access: yesFEBS Open Bio, EarlyView.
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji   +3 more
wiley   +1 more source

Deep clustering of longitudinal data [PDF]

open access: yesarXiv, 2018
Deep neural networks are a family of computational models that have led to a dramatical improvement of the state of the art in several domains such as image, voice or text analysis. These methods provide a framework to model complex, non-linear interactions in large datasets, and are naturally suited to the analysis of hierarchical data such as, for ...
arxiv  

The Long Term Effects of a 12‐Session Community Exercise Program on Health Measures in Cancer Patients

open access: yesAging and Cancer, EarlyView.
ABSTRACT Purpose To assess the long‐term effects of a community cancer exercise program on quality of life, fatigue, weight, waist circumference, physical activity levels, lower extremity strength, body mass index (BMI), heart rate, and blood pressure, across non‐metastatic and metastatic patients.
Isaac Oppong, Roozbeh Naemi
wiley   +1 more source

Enhanced analysis of gating latency in 0.35T MR‐linac through innovative time synchronization of a motion phantom and plastic scintillation detector

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose This study aims to evaluate how different gantry angles, breathing rates (BPM), cine image speeds, and tracking algorithms affect beam on/off latency and the subsequent impact on target dose for a 0.35T MR‐Linac with a 6 MV FFF beam.
Mateb Al Khalifa   +4 more
wiley   +1 more source

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