Results 61 to 70 of about 3,168,034 (334)
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Integrated noninvasive diagnostics for prediction of survival in immunotherapy
Immuno-Oncology and TechnologyBackground: Integrating complementary diagnostic data sources promises enhanced robustness in the predictive performance of artificial intelligence (AI) models, a crucial requirement for future clinical validation/implementation.
M. Yeghaian +10 more
doaj +1 more source
Signal Detection and Monitoring Based on Longitudinal Healthcare Data
Pharmaceutics, 2012 Post-marketing detection and surveillance of potential safety hazards are crucial tasks in pharmacovigilance. To uncover such safety risks, a wide set of techniques has been developed for spontaneous reporting data and, more recently, for longitudinal ...
Iris Pigeot, Marc Suling
doaj +1 more source
Functional linear regression analysis for longitudinal data
, 2006 We propose nonparametric methods for functional linear regression which are designed for sparse longitudinal data, where both the predictor and response are functions of a covariate such as time.
Müller, Hans-Georg +2 more
core +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Influence of User Preferences on the Revealed Utility Factor of Plug-In Hybrid Electric Vehicles
World Electric Vehicle Journal, 2019 Plug-in hybrid electric vehicles (PHEVs) are an effective intermediate vehicle technology option in the long-term transition pathway towards light-duty vehicle electrification.
Seshadri Srinivasa Raghavan, Gil Tal
doaj +1 more source
Evolution of the longitudinal structure function at small x
, 2014 We derive an approximation approach to evolution of the longitudinal structure function, by using a Laplace-transform method. We solve the master equation and derive the longitudinal structure function as a function of the initial condition $F_{L}(x,Q^{2}
Boroun, G. R.
core +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Model-Free Feature Screening Based on Data Aggregation for Ultra-High-Dimensional Longitudinal Data
StatsUltra-high dimensional longitudinal data feature screening procedures are widely studied, but most require model assumptions. The screening performance of these methods may not be excellent if we specify an incorrect model.
Junfeng Chen +3 more
doaj +1 more source
Crossing MGLS with the Middle Grades Research Agenda: A Guide for Researchers [PDF]
, 2018 For the past several years, leaders in middle grades education research have strengthened their call for more methodologically robust quantitative research to address important questions in the field.
Bishop, Penny A, Olofson, Mark W.
core +2 more sources