Validity and Reliability of Clinical and Patient‐Reported Outcomes in Multisystem Proteinopathy 1
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Valosin‐containing protein (VCP)‐associated multisystem proteinopathy 1 (MSP1) is caused by variants in the VCP gene. MSP1 results in various phenotypes including progressive myopathy, Paget's disease of bone, frontotemporal dementia, amyotrophic lateral sclerosis, and parkinsonism, among others.
Lindsay N. Alfano +15 more
wiley +1 more source
CROSS‐SECTIONAL VERSUS LONGITUDINAL DATA: AN EMPIRICAL COMPARISON OF MEAN DIFFERENCES IN ACADEMIC GROWTH [PDF]
, 1969 Thomas L. Hilton, Cathleen Patrick
openalex +1 more source
Histone Deacetylase 6 Brain PET in Amyotrophic Lateral Sclerosis‐Frontotemporal Spectrum Disorder
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective [18F]EKZ‐001 is a positron emission tomography (PET) tracer targeting histone deacetylase 6 (HDAC6), an enzyme responsible for intracellular transport and clearance of misfolded proteins. HDAC6 modulation is a promising treatment strategy in neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS).
Greet Vanderlinden +15 more
wiley +1 more source
Uncovering Longitudinal Healthcare Utilization from Patient-Level Medical Claims Data [PDF]
arXiv, 2016 The objective of this study is to introduce methodology for studying longitudinal claims data observed at the patient level, with inference on the heterogeneity of healthcare utilization behaviors within large healthcare systems such as Medicaid. The proposed approach is model-based, allowing for visualization of longitudinal utilization behaviors ...
arxiv
Serum complement levels in rheumatoid arthritis. A longitudinal study of 43 cases with correlation of clinical and serological data including rheumatoid factor and thermolabile inhibitor of the F-II L.P. test. [PDF]
, 1965 Adalbert F. Schubart +5 more
openalex +1 more source
Myostatin Levels in SMA Following Disease‐Modifying Treatments: A Multi‐Center Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective This study investigated myostatin levels in SMA patients receiving disease‐modifying therapies (DMTs) to understand their relationship with treatment duration and functional status. Methods Our study includes both cross‐sectional and longitudinal analyses of myostatin levels in treated SMA patients.
Fiorella Piemonte +23 more
wiley +1 more source
Longitudinal Single Bunch Instability Study on BEPCII [PDF]
arXiv, 2013 In order to study the single bunch longitudinal instability in BEPCII, experiments on the positron ring (BPR) for the bunch lengthening phenomenon were made. By analyzing the experimental data based on Gao's theory, the longitudinal loss factor for the bunch are obtained. Also, the total wake potential and the beam current threshold are estimated.
arxiv
SOME NEW DATA ON THE LONGITUDINAL DIMENSIONS OF PLANETARY WAVES [PDF]
, 1960 Jay S. Winston
openalex +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amygdala enlargement has been the subject of controversial studies regarding its significance in terms of pathogenicity both in epilepsy and in psychiatric comorbidities such as anxiety, depression, and post‐traumatic stress disorder.
Hélène Mourre +15 more
wiley +1 more source
EM-REML estimation of covariance parameters in Gaussian mixed models for longitudinal data analysis [PDF]
, 2000 Jean‐Louis Foulley +2 more
openalex +3 more sources