Results 51 to 60 of about 14,354,496 (289)

Socioeconomic inequalities in blood pressure: co-ordinated analysis of 147,775 participants from repeated birth cohort and cross-sectional datasets, 1989 to 2016

BMC Medicine, 2020
Background High blood pressure (BP) is a key modifiable determinant of cardiovascular disease and a likely determinant of other adverse health outcomes.
David Bann, Meg Fluharty, Rebecca Hardy, Shaun Scholes   +3 more
doaj   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

A data driven approach to address missing data in the 1970 British birth cohort

BMC Medical Research Methodology
Background Missing data may induce bias when analysing longitudinal population surveys. We aimed to tackle this problem in the 1970 British Cohort Study (BCS70). Methods We utilised a data-driven approach to address missing data issues in BCS70.
Michail Katsoulis, Martina K. Narayanan, Brian Dodgeon, George B. Ploubidis, Richard J. Silverwood   +4 more
doaj   +1 more source

Knee extension rate of torque development and peak torque: associations with lower extremity function

Journal of Cachexia, Sarcopenia and Muscle, 2018
Background With aging, the ability to generate muscle force decreases, contributing to declines in physical functions such as walking. While most studies assess muscle force by peak torque, the rate of torque development (RTD) reflects a dynamic ...
Yusuke Osawa, Stephanie A. Studenski, Luigi Ferrucci   +2 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Handling attrition and non-response in longitudinal data [PDF]

, 2009
oai:edrev.asu.edu:article/21Procedures for handling attrition and missing data in longitudinal studies are discussed. A multiple imputation (MI) strategy is developed that can be applied to complex multilevel data.
Goldstein, H, Goldstein, Harvey
core   +1 more source

The validation of short eating disorder, body dysmorphia, and Weight Bias Internalisation Scales among UK adults

Journal of Eating Disorders
Background When collecting data from human participants, it is often important to minimise the length of questionnaire-based measures. This makes it possible to ensure that the data collection is as engaging as possible, while it also reduces response ...
Dorottya Lantos, Darío Moreno-Agostino, Lasana T. Harris, George Ploubidis, Lucy Haselden, Emla Fitzsimons   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Is studying medicine good for your health? Long-term health outcomes of a cohort of clinical medicine graduates in England and Wales in the ONS Longitudinal Study

BMJ Open, 2021
Objective To quantify the potential protective effect on health associated with study of a clinical medicine degree.Design Prospective population-based cohort data collected at census and linked over time: cohort born before 1976 and survived to 2011 ...
Nicola Shelton, Oliver Duke-Williams, Laura van der Erve, Jack Britton, Wei Xun   +4 more
doaj   +1 more source