Results 51 to 60 of about 14,877,772 (287)
ABSTRACT Transitioning from pediatric to adult care is a high‐risk period for individuals with sickle cell disease (SCD). An initial observation at one academic medical center suggested a sex‐based disparity in clinic populations, prompting a national investigation.
Laurie J. Duckworth +5 more
wiley +1 more source
From imputation to impact [PDF]
The topics included in this issue range from the imputation of missing data in longitudinal surveys to demonstrating that their results make a difference in the public arena – both challenges to our research field the world over.
Joshi, Heather
core +1 more source
ABSTRACT Background Heavy menstrual bleeding (HMB) is a common condition among adolescents and young adults (AYAs) and is the leading cause of iron deficiency anemia (IDA) in this population. Growing evidence suggests that social determinants of health (SDOH) influence menstrual bleeding patterns, access to care, and treatment. However, no studies have
Maria Carter‐Febres +6 more
wiley +1 more source
copyright UK Data Service and data collection copyright owner.CLOSER (Cohort and Longitudinal Studies Enhancement Resources) aims to maximise the use, value and impact of longitudinal studies, both at home and abroad.
Cohort and Longitudinal Studies Enhancement Resources
core +2 more sources
Objective To quantify the potential protective effect on health associated with study of a clinical medicine degree.Design Prospective population-based cohort data collected at census and linked over time: cohort born before 1976 and survived to 2011 ...
Nicola Shelton +4 more
doaj +1 more source
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono +7 more
wiley +1 more source
Plasma lipids connecting olfaction with cognition and physical function
Olfactory deficit is an early sign of neurodegenerative diseases, such as Alzheimer’s disease (AD), and is related to age-related cognitive and physical function decline. However, underlying biological processes are not fully understood.
Erin E. Greig +3 more
doaj +1 more source
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Integrating public engagement to promote transparent data use in a new UK-wide birth cohort
Public engagement is an important mechanism for ensuring that the voices of the public are integrated into study design and data use. The commissioning of a new UK-wide birth cohort study by the UKRI Economic and Social Research Council (ESRC), the ...
Alyce Raybould +6 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source

