Results 91 to 100 of about 4,095 (248)

From Diagnosis to Disease Staging: Multisite Validation of Cerebrospinal Fluid Molecular Tests in Multiple Sclerosis

Annals of Neurology, Volume 99, Issue 2, Page 328-340, February 2026.
Objective The growing demand for personalized treatment in multiple sclerosis (MS) highlights the need for more precise biomarkers that can outperform magnetic resonance imaging and clinical assessment in patient stratification. Advances in multiplex proteomic technologies suggest that cerebrospinal fluid (CSF) analysis at MS onset may not only improve
Laura Ghezzi, Peter Kosa, Mark Greenwood, Enrique Alvarez, C. L. Freedman, Anne H. Cross, Francesca Pace, Mark S. Freedman, Joanna Kocot, Laura Piccio, Bibiana Bielekova   +10 more
wiley   +1 more source

A sporadic case of holocord tuberculous transverse myelitis with arachnoiditis

The Egyptian Journal of Radiology and Nuclear Medicine, 2022
Background Tubercular infection of the brain and spine is relatively common in endemic regions of the world. Central nervous system tuberculosis can have varied manifestations. The familiar imaging findings are hydrocephalus, ring-enhancing tuberculomas,
Sukrati Ranjan, Rahul Dev, Miranda Devi Keisham   +2 more
doaj   +1 more source

The history of neuromyelitis optica [PDF]

, 2013
The discovery of a novel serum autoantibody (termed NMO-IgG or AQP4-Ab) in a subset of patients in 2004 has revived interest in neuromyelitis optica (NMO).
Jarius, Sven, Wildemann, Brigitte
core   +1 more source

The First Case of Longitudinal Extensive Transverse Myelitis (LETM) Following the First Dose Vaccination with Sinopharm Vaccine [PDF]

, 2022
Sara Bagherieh, Narges Ebraimi, Omid Mirmosayyeb, Mahdi Barzegar, Vahid Shaygannejad   +4 more
openalex   +1 more source

Microbial‐Immune Interplay in CNS Autoimmune Diseases: Lessons from Animal Models and Clinical Studies

European Journal of Immunology, Volume 56, Issue 2, February 2026.
Mechanism of action of the intestinal microbiota on CNS autoimmune diseases. Environmental factors shape gut microbiota composition; dysbiosis alters microbial metabolites and antigenic signals. These modulate innate and adaptive immunity, affect barrier integrity, and influence CNS‐resident cells such as microglia and astrocytes, contributing to ...
Matteo Ceccon, Francesca Ronchi
wiley   +1 more source

Multidimensional Assessment of Neurological Adverse Reactions Related to PD‐1 Inhibitors: A Real‐World Pharmacovigilance Study

CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
This pharmacovigilance study systematically analyzed PD‐1 inhibitor–associated neurological adverse events using FAERS data from 2014 to 2024. Central nervous system toxicities, including encephalitis and brainstem encephalitis, were most prominent. Older age, female sex, specific cancer types, and combination therapies increased the risk, with most ...
Xiaofeng Hu, Xiaoli Wang, Bufu Tang, Dehuan Zhang, Rongbing Cai, Hui Jiang, Yaling Lin, Yiheng Song, Yiou Wang, Hairuo Huang, Dandan Guo, Xubin Sun, Hongjie Fan   +12 more
wiley   +1 more source

Teaching Neuro Images : Longitudinally extensive transverse myelitis in MELAS [PDF]

Neurology, 2016
A 16-year-old girl presented with acute-onset flaccid quadriparesis with urinary incontinence. Medical history unveiled generalized epilepsy since age 7 years and status epilepticus 3 years before. Multisystem compromise was absent. Family history was unremarkable.
Paulo Victor Sgobbi de, Souza, Wladimir Bocca Vieira de Rezende, Pinto, Acary Souza Bulle, Oliveira   +2 more
openaire   +2 more sources

Exclusions affect representativeness of Alzheimer's disease trial participants

Alzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 12, Issue 1, January/March 2026.
Abstract BACKGROUND This study assessed how medical exclusion criteria of a prevention Alzheimer's disease trial impact potential eligibility and sample characteristics. METHODS Medical exclusion criteria from the Anti‐Amyloid Treatment in Asymptomatic Alzheimer's Disease (A4) trial were applied to N = 3695 participants from the population‐based Health
Miriam T. Ashford, Rachana Tank, Mohammed U. Kabeto, Rachel L. Nosheny, Michael W. Weiner, David R. Weir, Kenneth M. Langa   +6 more
wiley   +1 more source

Iatrogenic Kaposi’s sarcoma following immunosuppressive treatment of the recurrent longitudinally extensive transverse myelitis [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2018
Introduction. Iatrogenic Kaposi’s sarcoma (KS) represents a multifocal, angioproliferative tumor that develops in patients undergoing immunosuppressive treatment and is considered to be induced by activation of latent human herpes virus type 8 (HHV8 ...
Lalošević Jovan, Škiljević Dušan, Dujmović Irena, Drulović Jelena, Medenica Ljiljana   +4 more
doaj   +1 more source

Leber Hereditary Optic Neuropathy and Longitudinally Extensive Transverse Myelitis [PDF]

, 2017
Leber Hereditary Optic Neuropathy is an inherited optic neuropathy caused by mitochondrial DNA point mutations leading to sudden, painless loss of vision. We report a case of an 8-year-old boy presenting with a radiological phenotype of longitudinally extensive transverse myelitis on a background of severe visual impairment secondary to Leber ...
Bursle, C, Riney, K, Stringer, J, Moore, D, Gole, G, Kearns, LS, Mackey, DA, Coman, D   +7 more
openaire   +3 more sources