Results 71 to 80 of about 2,542 (166)

Efficacy and Safety of Multidisciplinary Sandwich Regimen in AQP4‐IgG+ NMOSD With Preconception B‐Cell Depletion During Perigravidity

CNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
We described a multidisciplinary “sandwich” regimen combining preconception B‐cell depletion, gestational AZA‐steroid bridging and postpartum retreatment. In 7 of 8 AQP4‐IgG‐positive NMOSD women, this strategy achieved good maternal relapse control, together with favorable fetal safety and normal infant neurodevelopment within one‐year follow‐up ...
Li Xiao, Gengxin Lu, Qian Gao, Feiyan Wan, Zhenze Lu, Wei Qiu, Chengfang Xu, Yaxin Lu, Lejia Xu, Tingting Xia, Jiajing Chao, Yu Fu, Zhuanggui Chen, Rui Li, Yanyu Chang, Yuge Wang, Bing Qin, Yaqing Shu   +17 more
wiley   +1 more source

Cognitive Performance and Psychological Characteristics in Patients With Clinically Isolated Syndrome: A Case–Control Study

Health Science Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background and Aim Clinically isolated syndrome (CIS) may represent the earliest clinical manifestation of multiple sclerosis (MS). Cognitive and psychological impairments may appear during the early phase of CIS, even in the absence of significant neurological disability.
Sahar Jamshidi, Nastaran Majdinasab, Ebrahim Behzad, Sayed Ali Marashi, Shooka Mohammadi   +4 more
wiley   +1 more source

Serum GFAP and Age Accurately Distinguish AQP4‐IgG Positive and Double Seronegative NMOSD From MOGAD After a Recent Attack

European Journal of Neurology, Volume 33, Issue 10, October 2026.
After a recent NMOSD attack, serum GFAP and age together provide a simple and powerful way to distinguish AQP4‐IgG NMOSD from MOGAD and related disorders. In 240 patients evaluated within 90 days of an attack from a 640‐patient cohort, this combination achieved high diagnostic accuracy (AUC up to 0.95).
Manon Rival, Fabien Rollot, Sabine Laurent‐Chabalier, Romain Casey, Illiasse El Bahi, Guillaume Brocard, Romain Marignier, Sophie Trouillet‐Assant, Sandra Vukusic, Agnès Fromont, David Axel Laplaud, Guillaume Mathey, Elisabeth Maillart, Laure Michel, Aurélie Ruet, Pierre Labauge, Xavier Ayrignac, Hélène Zephir, Jonathan Ciron, Jérôme de Sèze, Arnaud Kwiatkowski, Caroline Papeix, Pierre Branger, Christine Lebrun‐Frenay, Eric Berger, Pierre Clavelou, Olivier Heinzlef, Jean Pelletier, Abdullatif Al‐Khedr, Olivier Casez, Bertrand Bourre, Alain Créange, Thomas David, Laurent Magy, Jean‐Philippe Camdessanche, Inès Doghri, Amélie Dos Santos, Thibault Mura, Hanane Agherbi, Eric Thouvenot, for the OFSEP Group and NOMADMUS Investigators, Nicolas Collongues, Céline Cognet, Mireille Desille‐Dugast, Nathalie Dufay, Mathilde Berthome, Michael Hisbergues, Sylvain Lehmann, Laurence Liang, Céline Loiseau, Julie Marechal, Estelle Nisse, Françoise Durand‐Dubief, François Cotton, Bertrand Audoin, Mikael Cohen, Nicolas Collongues, Romain Deschamps   +57 more
wiley   +1 more source

Longitudinally extensive transverse myelitis with mycobacterium tuberculosis infection [PDF]

Acta Neurologica Belgica, 2021
Le Fang, Yushuang Gong, Kai Han, Yalin Lv, Miao Li, Jie Wang   +5 more
openaire   +2 more sources

A case of tubercular meningoencephalitis with transverse myelitis

Radiology Case Reports
Central nervous system tuberculosis accounts for approximately 1% of all tuberculosis cases. Transverse myelitis is an extremely rare manifestation of central nervous system tuberculosis, involving 1 or more vertebral segments of the spinal cord. However,
Abhikanta Khatiwada, MD, Sharada K C, MD, Anamika Jha, MD, Sashi Sekhar Singh, MD   +3 more
doaj   +1 more source

Longitudinally Extensive Transverse Myelitis With and Without Aquaporin 4 Antibodies

JAMA Neurology, 2013
Aquaporin 4 antibody (AQP4-Ab)-negative patients with longitudinally extensive transverse myelitis (LETM) behave differently from those with AQP4-Ab. Aquaporin 4 antibody-negative neuromyelitis optica (NMO) is rare when good assays are used.To assess if AQP4-Ab-negative patients with LETM share similar disease characteristics with AQP4-Ab-positive ...
Kitley, J, Leite, M, Küker, W, Quaghebeur, G, George, J, Waters, P, Woodhall, M, Vincent, A, Palace, J   +8 more
openaire   +2 more sources

Leber Hereditary Optic Neuropathy and Longitudinally Extensive Transverse Myelitis [PDF]

, 2017
Leber Hereditary Optic Neuropathy is an inherited optic neuropathy caused by mitochondrial DNA point mutations leading to sudden, painless loss of vision. We report a case of an 8-year-old boy presenting with a radiological phenotype of longitudinally extensive transverse myelitis on a background of severe visual impairment secondary to Leber ...
Bursle, C, Riney, K, Stringer, J, Moore, D, Gole, G, Kearns, LS, Mackey, DA, Coman, D   +7 more
openaire   +5 more sources

Seronegative Neuromyelitis Optica Spectrum - The challenges on disease definition and pathogenesis

Arquivos de Neuro-Psiquiatria, 2014
Neuromyelitis optica spectrum disorders (NMOSD) are characterized by severe optic neuritis and/or longitudinally extensive transverse myelitis, and some brain lesions are also unique to NMOSD.
Douglas Kazutoshi Sato, Dagoberto Callegaro, Marco Aurélio Lana-Peixoto, Ichiro Nakashima, Kazuo Fujihara   +4 more
doaj   +1 more source

Optical coherence tomography and subclinical optical neuritis in longitudinally extensive transverse myelitis

Annals of Indian Academy of Neurology, 2017
Objective: The aim is to compare the retinal nerve fiber layer (RNFL) thickness of longitudinally extensive transverse myelitis (LETM) eyes without previous optic neuritis with that of healthy control subjects.
Prakash Kumar Sinha, Deepika Joshi, Virendra Pratap Singh, Sujit Deshmukh, Usha Singh, Abhishek Pathak, Vijay Nath Mishra, Rameshwar Nath Chaurasia, Vivek Sharda, Garima Gupta   +9 more
doaj   +1 more source

Longitudinally extensive transverse myelitis associated with scrub typhus: A case report

Asian Pacific Journal of Tropical Medicine
Rationale: Longitudinally extensive transverse myelitis (LETM) is a rare inflammatory demyelinating disease predominantly associated with autoimmune and inflammatory disorders.
Amit Kumar, Rajesh Chetiwal, Shweta Tanwar   +2 more
doaj   +1 more source