Results 141 to 150 of about 35,022 (298)

Phenotyping of acute heart failure with preserved ejection fraction: real‐world outcomes in a cohort of older patients

open access: yesInternal Medicine Journal, EarlyView.
Abstract Background Previous studies have identified distinct subgroups (phenogroups) of patients with heart failure with preserved ejection fraction (HFpEF). Aims This study aims to identify distinct phenotypes in older patients with HFpEF hospitalised for acute heart failure (AHF) and investigate the relationship between subgroups and outcomes ...
Maria Livia Burzo *   +10 more
wiley   +1 more source

Predictors of a Gabapentinoid–Loop‐Diuretic Prescribing Cascade in U.S. Nursing Home Residents

open access: yesJournal of the American Geriatrics Society, EarlyView.
Among 23,544 older adult long‐stay nursing home residents who initiated a gabapentinoid in the nursing home (2016–2022), 4.2% experienced a loop diuretic prescribing cascade within 90 days. Predictors of the prescribing cascade included older age, higher medication burden (≥ 15 medications), current receipt of non‐loop diuretics, and titration of ...
Kaleen N. Hayes   +7 more
wiley   +1 more source

Angiotensin-Neprilysin Inhibitor Therapy: A Retrospective Chart Study

open access: yesINNOVATIONS in Pharmacy
Background: Guideline-directed medical therapy in patients with systolic heart failure (HF) has demonstrated improvement in morbidity and mortality rates.
Roda Plakogiannis   +3 more
doaj   +1 more source

Making the Old New Again Through the Process of Recombinant Innovation

open access: yesJournal of Product Innovation Management, EarlyView.
ABSTRACT Academic Summary Recombinant innovation—the process through which atypical and unexpected combinations of knowledge generate novel outcomes—is a critical driver of organizational distinctiveness and market transformation. While prior research has focused on firm‐ and industry‐level mechanisms, less attention has been given to multilevel ...
Vittoria Magrelli   +4 more
wiley   +1 more source

Association of Diuretic Dosage With Outcomes in Patients With Hemodynamically Significant Isolated Tricuspid Valve Regurgitation

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Tricuspid valve surgery is recommended for severe isolated tricuspid regurgitation (TR) if symptoms persist despite optimal medical therapy. The definition of optimal therapy for TR is unclear beyond managing underlying conditions.
Vidhu Anand   +12 more
doaj   +1 more source

The Association Between Disordered Eating and Sleep in Non‐Clinical Populations—A Systematic Review and Meta‐Analysis

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Sleep and disordered eating behaviours may be linked through physiological and psychological mechanisms; yet, no review has systematically investigated the relationship between different sleep indicators and disordered eating behaviours and cognitions outside a clinical context.
Marie‐Christine Opitz   +49 more
wiley   +1 more source

Transjugular Leadless Pacemaker Implantation in an Adolescent With Central Hypoventilation Syndrome: A Case Report

open access: yesPacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Background Permanent pacing in pediatric patients is complicated by small body size, vascular access limitations, and the need for durable long‐term management. Leadless pacemakers offer an emerging alternative that minimizes infection and lead‐related complications, yet vascular access remains a key challenge in young patients.
Marzia Giaccardi   +4 more
wiley   +1 more source

Perioperative outcomes of 65 dogs and 15 cats undergoing lung lobectomies with a hilar circumferential ligature

open access: yesVeterinary Surgery, EarlyView.
Abstract Objective To report perioperative morbidity and mortality in dogs and cats undergoing total lung lobectomy using a hilar circumferential ligature (HCL). Study design Retrospective clinical study. Sample population Client owned dogs (n = 65) and cats (n = 15).
Anna M. Cronin   +5 more
wiley   +1 more source

Sodium–glucose cotransporter 2 inhibitors for hypertension in cardiovascular–kidney–metabolic syndrome

open access: yesExperimental Physiology, EarlyView.
Abstract The antihypertensive mechanism of sodium–glucose cotransporter 2 (SGLT2) inhibitors has been traditionally attributed to osmotic diuresis. However, emerging evidence reveals multifaceted mechanisms beyond diuresis, including regulation of the renin–angiotensin–aldosterone system, sympathetic nervous system suppression, ion homeostasis ...
Chunxiang Xu   +5 more
wiley   +1 more source

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