Results 181 to 190 of about 17,677 (210)

Revisiting the Incidence of Hypercalcemia in Contemporary Diagnoses of Pediatric Patients With Solid Tumors

Pediatric Blood &Cancer, Volume 72, Issue 12, December 2025.
ABSTRACT Background Hypercalcemia is rarely observed in pediatric patients with cancer. However, rare cases of renal insufficiency and osteoporosis have been reported as severe consequences. Published literature focuses predominantly on hypercalcemia in pediatric hematologic malignancies, precluding causative associations with solid tumor disease ...
Felicia Y. Ho, Dajana Alku, Chalinee Monsereenusorn, Nan Chen, Wendy B. London, Allison F. O'Neill   +5 more
wiley   +1 more source

Comparative cardiovascular risk of sulfonylureas with low‐ and high‐affinities for cardiac mitochondrial adenosine triphosphate‐sensitive potassium channels versus dipeptidyl peptidase‐4 inhibitors in patients with type 2 diabetes: A cohort study

Diabetes, Obesity and Metabolism, Volume 27, Issue 12, Page 7502-7513, December 2025.
Abstract Aims To individually evaluate the cardiovascular safety of low‐ and high‐affinity cardiac mitochondrial ATP‐sensitive potassium (mitoKATP) channel sulfonylureas by comparing each to dipeptidyl peptidase‐4 inhibitors (DPP‐4i), a generally cardiovascular‐neutral comparator, given prior evidence suggesting greater cardiovascular risk with high ...
Mei‐Hsiu Chen, Liang‐Yu Lin, Tung‐Ying Hung, Tzu‐Chieh Lin, Chia‐Yu Li, Tzu‐Han Lin, Yi‐Hsuan Chen, Jun‐Ting Liou, Meng‐Ting Wang   +8 more
wiley   +1 more source

Efficacy and Field Safety of Ilunocitinib for the Control of Allergic Dermatitis in Client‐Owned Dogs: A Multicenter, Double‐Masked, Randomised, Placebo‐Controlled Clinical Trial

Veterinary Dermatology, Volume 36, Issue 6, Page 825-837, December 2025.
Background: Inhibition of the Janus kinase pathway is an established treatment for allergic dermatitis. Objective: To evaluate the efficacy and safety of ilunocitinib for control of pruritus in dogs with allergic dermatitis in a randomised, double‐masked clinical trial.
Sophie Forster, Candace M. Trout, Simona Despa, Annette Boegel, Darren Berger, Stephen King   +5 more
wiley   +1 more source

Ototoxicity in Cancer Therapies

Oral Diseases, EarlyView.
Sady Selaimen da Costa, Nathaniel S. Treister, Caio Eddie de Melo Alves   +2 more
wiley   +1 more source

Acute kidney injury and morbi‐mortality associated with “triple whammy” combination: Systematic review and meta‐analysis

British Journal of Clinical Pharmacology, Volume 91, Issue 11, Page 3031-3041, November 2025.
Aims “Triple whammy” (TW) refers to the concomitant use of diuretics, renin‐angiotensin‐aldosterone system inhibitors (RAASI) and non‐steroidal anti‐inflammatory drugs (NSAIDs). The aim of this article is to analyse the association between TW exposure and acute kidney injury (AKI), among other morbi‐mortality outcomes.
Dulce María Calvo, Luis Carlos Saiz, Leire Leache, Maria Concepción Celaya, Marta Gutiérrez‐Valencia   +4 more
wiley   +1 more source

Budd–Chiari Syndrome in the Background of Chronic Kidney Disease: A Hypercoagulability‐Driven Association or Coincidence? A Case Report

Clinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT Budd–Chiari syndrome (BCS) is a rare condition characterized by hepatic venous outflow obstruction and is often associated with thrombosis or fibrous membranes (webs). To our knowledge, this is the first reported case of BCS occurring secondary to chronic kidney disease (CKD).
Anish Paudyal, Sanjay Dhungana, Sachin Bhatta, Sphurna Karki, Sapana Koirala, Parbatraj Regmi, Sagar Mani Regmi, Subhash Paudel   +7 more
wiley   +1 more source

Recurrent anorexia because of gastrointestinal beriberi in a home care patient

Journal of General and Family Medicine, Volume 26, Issue 6, Page 637-641, November 2025.
An elderly man with a history of unexplained anorexia and lethargy was diagnosed with gastrointestinal beriberi during home care. Empiric oral thiamine supplementation led to dramatic improvement, underscoring the importance of early recognition and treatment of thiamine deficiency.
Ren Kawamura, Tsuyoshi Enokihara, Yousuke Tsukinaga, Taro Shimizu   +3 more
wiley   +1 more source

Aryl Hydrocarbon Receptor in Health and Disease

MedComm, Volume 6, Issue 11, November 2025.
Based on the structure and ligands of AhR, this review introduces the AhR‐related signaling pathways and their roles in health and diseases. Agonists and antagonists of AhR as well as new strategies for treatment using the microbial–AhR axis are summarized. A prospect was made for the future use of AhR as a therapeutic target.
Haonan Li, Yufeng Fan, Jizheng Liu, Shumin Dong, Bin Wen, Yunfei Zhang, Xiaocui Wang, Xuemei Duan, Ying Hu, Ze Yan, Huifeng Shang, Yukai Jing   +11 more
wiley   +1 more source

A Rare Case of Chilaiditi Syndrome as a Driver of Chronic Respiratory Failure

Respirology Case Reports, Volume 13, Issue 11, November 2025.
This case describes a 66‐year‐old woman with chronic hypercapnic and hypoxemic respiratory failure due to Chilaiditi syndrome, an uncommon complication of bowel interposition between the liver and diaphragm. Her course was refractory to noninvasive ventilation and conservative bowel regimens, ultimately proving fatal.
Paige C. Adams, Daniel Kramer
wiley   +1 more source

Mechanistic Insights into Loop Diuretic Responsiveness in Heart Failure.

Clin J Am Soc Nephrol, 2019
Ellison DH, Ellison DH.
europepmc   +1 more source