Results 31 to 40 of about 35,022 (298)
A combined clinical and biomarker approach to predict diuretic response in acute heart failure [PDF]
Background: Poor diuretic response in acute heart failure is related to poor clinical outcome. The underlying mechanisms and pathophysiology behind diuretic resistance are incompletely understood.
Bloomfield, Daniel M. +16 more
core +4 more sources
Cardiac Dysfunction, Congestion and Loop Diuretics: their Relationship to Prognosis in Heart Failure [PDF]
Background: Diuretics are the mainstay of treatment for congestion but concerns exist that they adversely affect prognosis. We explored whether the relationship between loop diuretic use and outcome is explained by the underlying severity of ...
A Shoaib +38 more
core +2 more sources
Background Stroke is a major risk factor for osteoporosis and fractures. No study has evaluated the association between diuretic use and risk of vertebral fracture in stroke patients, although a considerable proportion of stroke patients are prescribed ...
Shu-Man Lin +3 more
doaj +1 more source
Improving Postdischarge Outcomes in Acute Heart Failure [PDF]
The global burden that acute heart failure (AHF) carries has remained unchanged over the past several decades (1). European registries (2–5) showed that 1-year outcome rates remain unacceptably high (Table 1) and confirm that hospitalization for AHF ...
Ambrosy, Andrew P. +8 more
core +1 more source
Aims Diuretic resistance is common in acute decompensated heart failure (ADHF). When loop diuretic monotherapy is ineffective, thiazides are often recommended as adjunctive therapy, but these agents have many side effects and are associated with worsened
Matthew Griffin +10 more
doaj +1 more source
Comparative effectiveness of enalapril, lisinopril, and ramipril in the treatment of patients with chronic heart failure: a propensity score-matched cohort study [PDF]
Background: Angiotensin converting enzyme inhibitors (ACEIs) are recommended as first-line therapy in patients with heart failure with reduced ejection fraction (HFrEF). The comparative effectiveness of different ACEIs is not known. Methods and results:
Agewall, Stefan +14 more
core +1 more source
Rolofylline, an adenosine A1−receptor antagonist, in acute heart failure [PDF]
Background: Worsening renal function, which is associated with adverse outcomes, often develops in patients with acute heart failure. Experimental and clinical studies suggest that counterregulatory responses mediated by adenosine may be involved. We
Bloomfield, Daniel M +15 more
core +1 more source
Effects of Sodium-Glucose Cotransporter 2 Inhibitors on Water and Sodium Metabolism
Sodium-glucose cotransporter 2 (SGLT2) inhibitors exert hypoglycemic and diuretic effects by inhibiting the absorption of sodium and glucose from the proximal tubule.
Jun Tang +9 more
doaj +1 more source
The effects of short-term omission of daily medication on the pathophysiology of heart failure [PDF]
Aims Pharmacological therapies for heart failure (HF) aim to improve congestion, symptoms, and prognosis. Failing to take medication is a potential cause of worsening HF.
Abraham +31 more
core +4 more sources
The treatment of edema in patients with nephrotic syndrome is generally managed by dietary sodium restriction and loop diuretics. However, edema does not improve in some patients despite adequate sodium restriction and maximal dose of diuretics.
Margaret Duffy +4 more
doaj +1 more source

