Results from a Phase 1 Study of Sodium Selenite in Combination with Palliative Radiation Therapy in Patients with Metastatic Cancer. [PDF]
, 2019 In preclinical studies, selenite had single agent activity and radiosensitized tumors in vivo. Here we report results from a Phase 1 trial in 15 patients with metastatic cancer treated with selenite (5.5 to 49.5 mg) orally as a single dose 2 hours before
Buyyounouski, Mark K +9 more
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The drugs, interacting with opiate receptors, and their application in gastroenterological practice
Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2011 The aim of review. To present information on the drugs nowadays used in gastroenterology, that interact with opiate receptors. Original positions. Opiate receptors in the body have been discovered about 35 years ago.
S. A. Bulgakov
doaj
Knowledge will Propel Machine Understanding of Content: Extrapolating from Current Examples
, 2017 Machine Learning has been a big success story during the AI resurgence. One particular stand out success relates to learning from a massive amount of data.
Anantharam Pramod +10 more
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Phase Ib/II Study of the Safety and Efficacy of Combination Therapy with Multikinase VEGF Inhibitor Pazopanib and MEK Inhibitor Trametinib In Advanced Soft Tissue Sarcoma. [PDF]
, 2017 Purpose: Pazopanib, a multireceptor tyrosine kinase inhibitor targeting primarily VEGFRs1–3, is approved for advanced soft tissue sarcoma (STS) and renal cell cancer. Downstream of VEGFR, trametinib is an FDA-approved MEK inhibitor used for melanoma.
Azad, Nilofe A. +10 more
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Functional characteristics of CYP3A4 allelic variants on the metabolism of loperamide in vitro
Infection and Drug Resistance, 2019 Qian-Meng Lin,1 Ying-Hui Li,1 Qian Liu,1 Ni-Hong Pang,1 Ren-Ai Xu,2 Jian-Ping Cai,3 Guo-Xin Hu1 1School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, People’s Republic of China; 2Department of Pharmacy, The First ...
Lin QM +6 more
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Journal of Experimental PharmacologyAkeberegn Gorems Ayele, Jeylan Sinba Kawet Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, EthiopiaCorrespondence: Akeberegn Gorems Ayele, Department of Pharmacology ...
Ayele AG, Kawet JS
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Development of a validated HPLC method for determination of an active component in Pycnocycla spinosa and tablets prepared from its extract [PDF]
, 2017 Introduction: Pycnocycla spinosa, a native plant of Iran with approved antispasmodic and antidiarrheal activities, could be a suitable candidate and an alternative remedy for the treatment of diarrhea and irritable bowel syndrome (IBS).
Asgari Borjlou, Nadia. +5 more
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Acacetin Alleviates Loperamide-Induced Functional Constipation by Inhibiting P53-Mediated Apoptosis in Colonic Epithelial Cells. [PDF]
Neurogastroenterol MotilChen X +9 more
europepmc +1 more source
A Case Report of Loperamide-Induced Respiratory Depression in Severe Gastrointestinal Inflammation Secondary to Chemotherapy. [PDF]
CureusThong JYH, Satyavolu R.
europepmc +1 more source