Results 91 to 100 of about 11,037 (196)
Endocrine Regulations, 2018 Objective. This study investigated whether the metformin (Met)-induced enhanced intestinal uptake of 2-deoxy-2-[18F]fluoro-D-glucose (18F-FDG) is reduced by loperamide, a long-acting anti-diarrheal agent. Methods.
Nobashi Tomomi +8 more
doaj +1 more source
Health Science ReportsBackground and Aims Loperamide and racecadotril are two antidiarrheal medications with different mechanisms of action that are highly important for the treatment of diarrhea as a result of infectious pathology.
Maryam Aziz +12 more
doaj +1 more source
Loperamide therapy for acute diarrhea in children: systematic review and meta-analysis.
PLoS Medicine, 2007 BackgroundLoperamide is widely used in adults for acute diarrhea. However, its use in children has been discouraged by the World Health Organization and the American Academy of Pediatrics owing to concerns over safety and efficacy in young children ...
Su-Ting T Li +2 more
doaj +1 more source
\u27 Loperamide overdose induces ventricular tachycardia with catastrophic outcomes\u27.
, 2020 Loperamide is a widely available, over-the-counter medication. The advent of the opioid epidemic has seen cases of loperamide overdose being reported. The common side effects of the medication can be relatively benign, but at high doses, loperamide can ...
Roomi, Sohaib +4 more
core
Effects of loperamide on tibial nerve compound action potential recordings.
, 2013 Examples (AF80.02C) of in vitro compound action potential (CAP) recordings from a small nerve bundle in the tibial nerve (arrow at bottom of figure indicates time of electrical stimulation). The size of the A-fiber CAP (grey box, insert) and C-fiber CAP (
Yun Guan (36851) +8 more
core +1 more source
Development of an Extemporaneous Loperamide Hydrochloride Syrup
Loperamide hydrochloride is the most commonly indicated molecule for the symptomatic treatment of acute and chronic diarrhea. However, its presentation in solid forms (tablets and capsules) limits its use in children and patients with dysphagia, while ...
Sarah BOUAMEUR +3 more
core +1 more source
Novel insights into mechanisms of inhibition of colonic motility by loperamide
Frontiers in NeuroscienceBackgroundIt is well known that opiates slow gastrointestinal (GI) transit, via suppression of enteric cholinergic neurotransmission throughout the GI tract, particularly the large intestine where constipation is commonly induced. It is not clear whether
Nabil Parkar +11 more
doaj +1 more source
Loperamide abuse cardiotoxicity. Should loperamide still be an over the counter medication?
, 2018 Loperamide is an over-the-counter anti-diarrheal medication that is inexpensive, easily accessible, and widely used. It is generally thought to be safe and effective without the potential for abuse.
Danielle C. Mihora +5 more
core +1 more source
Chronic spinal infusion of loperamide alleviates postsurgical pain in rats
, 2014 317-322Plantar incision in rat generates spontaneous pain behaviour. The opioid drug, morphine used to treat postsurgical pain produces tolerance after long-term administration.
Reeta, K H +2 more
core
Frontiers in PharmacologyAimsTo investigate the potential pharmacokinetic interactions of montmorillonite powder or loperamide on pyrotinib.MethodsThis study was a single-center, open-label, single-dose, fixed-sequence clinical trial conducted with healthy volunteers.
Yike Wang +14 more
doaj +1 more source