Results 71 to 80 of about 16,722 (204)

Novel and emerging antimicrobial strategies in the management of oral infections

Periodontology 2000, EarlyView.
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley   +1 more source

Evaluation of the Effect of Loperamide on the Cardiac Repolarization Interval Using Exposure–Response Analysis

Clinical and Translational Science
This analysis assessed the relationship between the plasma concentrations of loperamide and its N‐desmethyl loperamide meta‐ bolite (M1) and the potential QT interval prolongation at therapeutic and supratherapeutic doses.
Belén Valenzuela, Per Olsson Gisleskog, Iolanda Cirillo, Erwin Coenen, Jay Ariyawansa, Saberi Rana Ali, Samiha Takhtoukh, Juan José Pérez‐Ruixo, Oliver Ackaert   +8 more
doaj   +1 more source

Spondyloarthritis Associated With Collagenous Colitis—Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Collagenous colitis (CC) is a subtype of microscopic colitis characterized by chronic watery diarrhea with normal endoscopic findings. Although often linked to autoimmune diseases, its association with spondyloarthropathy (SpA) is rare and poorly documented.
Charlotte Bouvy, Abeline Kapuczinski, Sophiane Ibrahimi, Marc Léon, Nathalie Demeulenaere   +4 more
wiley   +1 more source

Effect of Flammulina velutipes (golden needle mushroom, eno-kitake) polysaccharides on constipation

Open Chemistry, 2018
Flammulina velutipes, (Curt. ex Fr.) Sing, a popularly edible fungus, has been widely used both as a restorative drug and a tonic food in China. In the current study, the effect of F.
Xin Xin, Zheng Kangwei, Niu Yingying, Song Miaomiao, Kang Wenyi   +4 more
doaj   +1 more source

Novel Insights Into the Association Between Parkinson's Disease and Constipation: Role of SHMT2 as a Promising Biomarker

CNS Neuroscience &Therapeutics, Volume 32, Issue 5, May 2026.
This study integrated bioinformatics analysis, cellular models, and PD/constipation mouse models to identify SHMT2 as a key shared biomarker linking Parkinson's disease and constipation. SHMT2 upregulation was validated in dopaminergic neurons and the enteric nervous system, highlighting its potential role in gut–brain axis dysfunction.
Jiehua Su, Kaixun Huang, Xiuna Jing, Xiaohuan Liu, Cheng Wen, Rulin Geng, Zhuoying Lai, Zhijia Ruan, Yiqiang Zhan, Danyu Lin, Enxiang Tao   +10 more
wiley   +1 more source

Worldwide Efficacy of Bismuth Subsalicylate in the Treatment of Travelers' Diarrhea [PDF]

, 2017
So far four randomized studies, three of them double-blind and placebo-controlled, have investigated the role of bismuth subsalicylate (BSS) in the treatment of travelers' diarrhea.
Steffen, Robert
core  

Pharmacological Evaluation of Methanolic Fruit Extract of Lannea coromandelica: Antioxidant, Cytotoxic, Antidiabetic, Antibacterial, Anti‐Inflammatory, and Sedative Activities

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
Phytochemical investigation of Lannea coromandelica through GC–MS and in silico analysis revealed diverse bioactive compounds with promising pharmacological potential. Integrated in vitro and in vivo assays demonstrated significant antioxidant, antidiabetic, antibacterial, anti‐inflammatory, and sedative activities, supporting its therapeutic relevance.
Priota Islam Meem, Zobayed Islam, Nazmul Hasan Eshaque, Md. Jahirul Islam Mamun, Khurram Murad Mojidee, Mohammad Badrudduja, Amit Kumar Dam, S. M. Moazzem Hossen   +7 more
wiley   +1 more source

Loperamide [PDF]

Reactions Weekly, 2020
  +6 more sources

Repurposing loperamide to overcome gefitinib resistance by triggering apoptosis independent of autophagy induction in KRAS mutant NSCLC cells

Cancer Treatment and Research Communications, 2020
Background: Gefitinib is an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) approved for first-line treatment of non-small cell lung cancer (NSCLC) with sensitizing EGFR mutations.
Christy W.S. Tong, Mia M.X. Wu, Vivi W. Yan, William C.S. Cho, Kenneth K.W. To   +4 more
doaj   +1 more source

Pharmacological treatment strategies to manage precipitated withdrawal following the administration of buprenorphine in opioid use disorder: A systematic review

Addiction, Volume 121, Issue 5, Page 1083-1099, May 2026.
Abstract Background and aims There has been limited evidence synthesis examining the treatment of buprenorphine precipitated opioid withdrawal (BPOW). We aimed to conduct the first systematic review to assess the clinical utility of any pharmacological intervention in the management of BPOW.
Emmert Roberts, Nicola Kalk, John Strang
wiley   +1 more source