Results 71 to 80 of about 11,037 (196)

Pulmonary Aspergillosis Treated With Oral Amphotericin B (MAT2203) in a Patient With HIV‐Related Cryptococcal Meningitis

Clinical Case Reports, Volume 14, Issue 5, May 2026.
Graphical abstract for a case of a 26‐year‐old female with advanced HIV disease, cryptococcal meningitis, and co‐infection with pulmonary aspergillosis. Both co‐infections were successfully treated with the novel oral lipid nanocrystal formulation of amphotericin B (MAT2203).
Enock Kagimu, Elizabeth Senkoro, Jane Gakuru, Morris K. Rutakingirwa, David R. Boulware, David B. Meya, Richard Kwizera   +6 more
wiley   +1 more source

REDUCTION OF THE PRODRUG LOPERAMIDE OXIDE TO ITS ACTIVE DRUG LOPERAMIDE IN THE GUT OF RATS, DOGS, AND HUMANS

, 2020
: Loperamide oxide (LOPOX) is a prodrug of loperamide (LOP)
Robert Woestenborghs, Willem Meuldermans, Janssen Pharmacokinetics, Karel Lavrijsen, JOS VAN HOUDT Dirk Van Dyck, Jos Heykants, Johan Monbaliu, Jan Hendrickx   +7 more
core  

Binding Site of Loperamide: Automated Docking of Loperamide in Human mu- and delta-Opioid Receptors

, 2008
Loperamide is a piperidine analogue, acting as agonist on peripheral opioid receptors, exhibiting affinity and selectivity for the cloned μ human opioid receptor compared with the δ human opioid receptor.
GRIECO P, MAZZONI O., CAMPIGLIA, Pietro, NOVELLINO E, DIURNO MV, DI BOSCO AM   +5 more
core   +1 more source

Loperamide positive deaths in Sweden 2012–2022 and Finland 2017–2022 : Fatal loperamide intoxication exclusively for Sweden

Loperamide, a potent μ-opioid receptor agonist used as an antidiarrheal drug, exhibits increased bioavailability at supratherapeutic doses, causing potential central nervous system effects. Its misuse for opioid withdrawal relief and euphoria can lead to
Jönsson, Anna K., Jönsson, Anna K.,, Kahn, Lydia, Jönsson, Anna, Kahn, Lydia,, Kriikku, Pirkko, Kriikku, Pirkko,   +6 more
core   +1 more source

The Effect of Acupuncture and Electro-acupuncture at ST41 on Intestinal Hypomotility Induced with Loperamide in Rats

Journal of Pharmacopuncture, 2009
Objectives : The purpose of this study was to compare the effect of acpuncture and electro-acupuncture of low(EA(L)) and high(EA(H)) frequency at Haegye(ST41) on intestinal hypomotility induced with loperamide in rats.
Lee Sang-mi, Lee Hyun
doaj   +1 more source

Differences in the Effectiveness of Uridine and Liriope platyphylla L. Between Complement Component 3 Deficiency- and Loperamide-Induced Constipation May Be Associated with the Alternative Regulation of the Cyclic Adenosine Monophosphate Downstream Signaling Pathway

Pharmaceuticals
Background/Objectives: Constipation can be induced in animal models through various factors such as loperamide (Lop) or complement component 3 (C3) deficiency.
Hee Jin Song, Eun Seo Park, Ji Eun Kim, Ayun Seol, Su Jeong Lim, Su Ha Wang, Ye Ryeong Kim, Ye Eun Ryu, So Hae Park, Jumin Park, Hyun Gu Kang, Dae Youn Hwang   +11 more
doaj   +1 more source

Anti-Diarrheal Activity of the Aqueous Leaf Extract of Ageratum Conyzoides in Wistar Rats

Journal of Applied Sciences and Environmental Management, 2015
The leaves of Ageratum conyzoides had been reportedly used in traditional medicine in the treatment of diarrhea. Thus its aqueous leaf extract was investigated for its possible anti-diarrheal property using castor oil induced diarrheal, charcoal meal ...
JOT Emudainohwo, EO Erhirhie, EG Moke
doaj   +2 more sources

PROCESS VALIDATION OF LOPERAMIDE HCl TABLET

, 2020
To survive in competitive market and to be successful, it is necessary to achieve high level of product quality. Loperamide HCl [4-(P-chlorophenyl)-4-hydroxy-N,N-dimethyldiphenyl-1-piperidine butyramide hydrochloride), is an opiate agonist widely used as
A K Seth, L M Jaiswal, Sonu D Naik, Dinesh Desai, R G Harkhani, Ashim Kumar Sen   +5 more
core  

Loperamide-Induced Cardiac Events: Case Reports and Review.

, 2021
Reports of cardiac arrhythmia secondary to loperamide toxicity have become increasingly common in the literature. We present two patients in their mid-20s, each having overdosed on loperamide and subsequently manifesting life-threatening cardiac ...
Krinock, Matthew, Nanda, Sudip, Stevens, Steven, Desai, Ravi V, MD, Modi, Vivek   +4 more
core  

Antidiarrhoeal activity of new thiazolidinones related to loperamide.

, 1996
A series of thiazolidinones related to loperamide was synthesized and evaluated for antidiarrhoeal activity in mice, using the castor oil test.
CAPASSO, FRANCESCO, DIURNO, MARIA VITTORIA, MAZZONI, ORAZIO, IZZO, ANGELO ANTONIO, BOLOGNESE, ADELE   +4 more
core   +2 more sources