Results 61 to 70 of about 592 (88)
Endocrine Regulations, 2018 Objective. This study investigated whether the metformin (Met)-induced enhanced intestinal uptake of 2-deoxy-2-[18F]fluoro-D-glucose (18F-FDG) is reduced by loperamide, a long-acting anti-diarrheal agent. Methods.
Nobashi Tomomi +8 more
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Loperamide therapy for acute diarrhea in children: systematic review and meta-analysis.
PLoS Medicine, 2007 BackgroundLoperamide is widely used in adults for acute diarrhea. However, its use in children has been discouraged by the World Health Organization and the American Academy of Pediatrics owing to concerns over safety and efficacy in young children ...
Su-Ting T Li +2 more
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Frontiers in PhysiologyBackgroundLoperamide, a μ-opioid receptor agonist that slows gastrointestinal transit, is widely used as an antidiarrheal agent and an experimental model of gastric dysmotility and functional dyspepsia (FD). However, transcriptomic alterations associated
Chunggeon Lee +10 more
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Novel insights into mechanisms of inhibition of colonic motility by loperamide
Frontiers in NeuroscienceBackgroundIt is well known that opiates slow gastrointestinal (GI) transit, via suppression of enteric cholinergic neurotransmission throughout the GI tract, particularly the large intestine where constipation is commonly induced. It is not clear whether
Nabil Parkar +11 more
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Frontiers in PharmacologyAimsTo investigate the potential pharmacokinetic interactions of montmorillonite powder or loperamide on pyrotinib.MethodsThis study was a single-center, open-label, single-dose, fixed-sequence clinical trial conducted with healthy volunteers.
Yike Wang +14 more
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The drugs, interacting with opiate receptors, and their application in gastroenterological practice
Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2011 The aim of review. To present information on the drugs nowadays used in gastroenterology, that interact with opiate receptors. Original positions. Opiate receptors in the body have been discovered about 35 years ago.
S. A. Bulgakov
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Journal of Experimental PharmacologyAkeberegn Gorems Ayele, Jeylan Sinba Kawet Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, EthiopiaCorrespondence: Akeberegn Gorems Ayele, Department of Pharmacology ...
Ayele AG, Kawet JS
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Functional characteristics of CYP3A4 allelic variants on the metabolism of loperamide in vitro
Infection and Drug Resistance, 2019 Qian-Meng Lin,1 Ying-Hui Li,1 Qian Liu,1 Ni-Hong Pang,1 Ren-Ai Xu,2 Jian-Ping Cai,3 Guo-Xin Hu1 1School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, People’s Republic of China; 2Department of Pharmacy, The First ...
Lin QM +6 more
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Molecular determinants of loperamide and -desmethyl loperamide binding in the hERG cardiac K channel
Bioorganic and Medicinal Chemistry Letters, 2018Roy Vaz, Jiesheng Kang, David Rampe
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