Results 61 to 70 of about 11,037 (196)

A case of yogurt central line‐associated bloodstream infection in a child with intestinal failure

open access: yesNutrition in Clinical Practice, Volume 41, Issue 3, Page 968-973, June 2026.
Abstract Central line‐associated bloodstream infections (CLABSI) are a significant cause of morbidity in children with intestinal failure (IF). Probiotic therapy is discouraged in patients with IF because of the increased risk of bacteremia with the probiotic organism.
Nasiha Rahim   +6 more
wiley   +1 more source

Evaluation of the Effect of Loperamide on the Cardiac Repolarization Interval Using Exposure–Response Analysis

open access: yesClinical and Translational Science
This analysis assessed the relationship between the plasma concentrations of loperamide and its N‐desmethyl loperamide meta‐ bolite (M1) and the potential QT interval prolongation at therapeutic and supratherapeutic doses.
Belén Valenzuela   +8 more
doaj   +1 more source

Clozapine‐induced diarrhea: A case report and mechanistic overview

open access: yesPsychiatry and Clinical Neurosciences Reports, Volume 5, Issue 2, June 2026.
Abstract Background Clozapine is an atypical antipsychotic that is highly effective in managing treatment‐resistant schizophrenia. However, its use is associated with a wide range of adverse effects, including agranulocytosis, seizures, sedation, and gastrointestinal issues such as constipation, and less commonly, diarrhea. While constipation is a well‐
Shahab Dastmardi, Soha Namazi
wiley   +1 more source

Evaluating Updated Fentanyl Immunoassays for Loperamide Interference

open access: yes
Background Loperamide is a µ-opioid receptor agonist that reduces intestinal peristalsis and is used to treat diarrhea. We previously described significant cross-reactivity of loperamide with 2 fentanyl immunoassays. Since then, new fentanyl immunoassays,
Geno, K. Aaron   +3 more
core   +1 more source

A mini‐review of chronic suppression of the hypothalamic–pituitary–adrenal axis in animals with P‐glycoprotein deficiency

open access: yesJournal of Small Animal Practice, Volume 67, Issue 6, Page 487-491, June 2026.
This mini‐review describes the pathophysiology of the disrupted hypothalamic–pituitary–adrenal axis in dogs, and probably cats, with the MDR1 (ABCB1) mutation, ABCB1‐1Δ in dogs and ABCB11930‐1931del TC in cats. Clinical consequences in affected animals are discussed and therapeutic interventions to consider are presented.
K. L. Mealey
wiley   +1 more source

Effect of Flammulina velutipes (golden needle mushroom, eno-kitake) polysaccharides on constipation

open access: yesOpen Chemistry, 2018
Flammulina velutipes, (Curt. ex Fr.) Sing, a popularly edible fungus, has been widely used both as a restorative drug and a tonic food in China. In the current study, the effect of F.
Xin Xin   +4 more
doaj   +1 more source

Clinical benefit and predictors of response to momelotinib after ruxolitinib failure: A cooperative real‐world study

open access: yesCancer, Volume 132, Issue 10, 15 May 2026.
Momelotinib demonstrated robust real‐world activity after ruxolitinib failure, with clinically meaningful improvements in spleen (≥50% spleen length reduction, 30.0%), symptoms (≥50% total symptoms score reduction, 39.2%), and anemia (major response, 35.7%) at 6 months.
Francesca Palandri   +41 more
wiley   +1 more source

Fulminant amoebic colitis following loperamide use.

open access: yes, 2007
Toxic megacolon is a rare consequence of infection with Entamoeba histolytica. We present such a patient in whom the course of disease may have been influenced by heavy loperamide use.
McGregor, Alastair   +3 more
core   +1 more source

Spondyloarthritis Associated With Collagenous Colitis—Case Report and Literature Review

open access: yesClinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Collagenous colitis (CC) is a subtype of microscopic colitis characterized by chronic watery diarrhea with normal endoscopic findings. Although often linked to autoimmune diseases, its association with spondyloarthropathy (SpA) is rare and poorly documented.
Charlotte Bouvy   +4 more
wiley   +1 more source

Repurposing loperamide to overcome gefitinib resistance by triggering apoptosis independent of autophagy induction in KRAS mutant NSCLC cells

open access: yesCancer Treatment and Research Communications, 2020
Background: Gefitinib is an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) approved for first-line treatment of non-small cell lung cancer (NSCLC) with sensitizing EGFR mutations.
Christy W.S. Tong   +4 more
doaj   +1 more source

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