Results 61 to 70 of about 9,440 (158)

Differences in the Effectiveness of Uridine and Liriope platyphylla L. Between Complement Component 3 Deficiency- and Loperamide-Induced Constipation May Be Associated with the Alternative Regulation of the Cyclic Adenosine Monophosphate Downstream Signaling Pathway

Pharmaceuticals
Background/Objectives: Constipation can be induced in animal models through various factors such as loperamide (Lop) or complement component 3 (C3) deficiency.
Hee Jin Song, Eun Seo Park, Ji Eun Kim, Ayun Seol, Su Jeong Lim, Su Ha Wang, Ye Ryeong Kim, Ye Eun Ryu, So Hae Park, Jumin Park, Hyun Gu Kang, Dae Youn Hwang   +11 more
doaj   +1 more source

Anti-Diarrheal Activity of the Aqueous Leaf Extract of Ageratum Conyzoides in Wistar Rats

Journal of Applied Sciences and Environmental Management, 2015
The leaves of Ageratum conyzoides had been reportedly used in traditional medicine in the treatment of diarrhea. Thus its aqueous leaf extract was investigated for its possible anti-diarrheal property using castor oil induced diarrheal, charcoal meal ...
JOT Emudainohwo, EO Erhirhie, EG Moke
doaj   +2 more sources

Loperamide abuse [PDF]

Canadian Medical Association Journal, 2017
Tony, Antoniou, David N, Juurlink
openaire   +2 more sources

Sustainable Utilization of Agricultural By-Products: in vivo investigation of the antidiarrheal potential of Litchi chinensis seed extract

Journal of Pharmacopuncture
Objectives: Diarrheal diseases remain a significant global health concern, with rising resistance to traditional pharmaceutical treatments. Litchi chinensis, a tropical fruit, is known for its medicinal properties, but its seed, which is often discarded ...
Mustakin Ahmed Shohel, Md. Humayan Kabir, Ivvala Anand Shaker, Sumaiya Siddika, Sheikh Arafat Rahman, Sumaiya Siddiquea, Nirmal Chandra Mahat, Tarique Muhammad Tawabul Islam, Md. Abul Kashem Tang   +8 more
doaj   +1 more source

Enhanced intestinal 2-deoxy-2-[18F]fluoro-D-glucose uptake under metformin is not fully suppressed by loperamide

Endocrine Regulations, 2018
Objective. This study investigated whether the metformin (Met)-induced enhanced intestinal uptake of 2-deoxy-2-[18F]fluoro-D-glucose (18F-FDG) is reduced by loperamide, a long-acting anti-diarrheal agent. Methods.
Nobashi Tomomi, Saga Tsuneo, Nakamoto Yuji, Shimizu Yoichi, Koyasu Sho, Ishimori Takayoshi, Watanabe Masao, Kimura Hiroyuki, Togashi Kaori   +8 more
doaj   +1 more source

Racecadotril Versus Loperamide for Acute Diarrhea of Infectious Origin in Adults: A Systematic Review and Meta‐Analysis

Health Science Reports
Background and Aims Loperamide and racecadotril are two antidiarrheal medications with different mechanisms of action that are highly important for the treatment of diarrhea as a result of infectious pathology.
Maryam Aziz, Laiba Urooj Malik, Erum Javed, Syeda Zuha Sami, Muhammad Maaz, Muhammad Arham Khan, Muhammad Farmaan, Omer Farooq, Umer Iqbal, Aashish Kumar, Syed Ali Arsal, Shafin Bin Amin, Inibehe Ime Okon   +12 more
doaj   +1 more source

Loperamide therapy for acute diarrhea in children: systematic review and meta-analysis.

PLoS Medicine, 2007
BackgroundLoperamide is widely used in adults for acute diarrhea. However, its use in children has been discouraged by the World Health Organization and the American Academy of Pediatrics owing to concerns over safety and efficacy in young children ...
Su-Ting T Li, David C Grossman, Peter Cummings   +2 more
doaj   +1 more source

Novel insights into mechanisms of inhibition of colonic motility by loperamide

Frontiers in Neuroscience
BackgroundIt is well known that opiates slow gastrointestinal (GI) transit, via suppression of enteric cholinergic neurotransmission throughout the GI tract, particularly the large intestine where constipation is commonly induced. It is not clear whether
Nabil Parkar, Nabil Parkar, Nabil Parkar, Nick J. Spencer, Luke Wiklendt, Trent Olson, Wayne Young, Wayne Young, Patrick Janssen, Warren C. McNabb, Julie E. Dalziel, Julie E. Dalziel   +11 more
doaj   +1 more source

Evaluation of the pharmacokinetic interactions of montmorillonite powder or loperamide on pyrotinib in healthy volunteers

Frontiers in Pharmacology
AimsTo investigate the potential pharmacokinetic interactions of montmorillonite powder or loperamide on pyrotinib.MethodsThis study was a single-center, open-label, single-dose, fixed-sequence clinical trial conducted with healthy volunteers.
Yike Wang, Dai Li, Dai Li, Tong Zhang, Sumei Xu, Sumei Xu, Yanxin Zhang, Yanxin Zhang, Kaijing Zhao, Shaorong Li, Kai Shen, Xiaomin Li, Xiaomin Li, Pingsheng Xu, Pingsheng Xu   +14 more
doaj   +1 more source

The drugs, interacting with opiate receptors, and their application in gastroenterological practice

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2011
The aim of review. To present information on the drugs nowadays used in gastroenterology, that interact with opiate receptors. Original positions. Opiate receptors in the body have been discovered about 35 years ago.
S. A. Bulgakov
doaj