Results 41 to 50 of about 9,440 (158)

Clinical Trial: Effectiveness and Safety of a Novel Anal Insert Device for Treatment of Faecal Incontinence

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 5, Page 603-614, September 2026.
StaySure is a novel anal insert device that safely and effectively treats medically refractory faecal incontinence. Treatment reduced incontinence episodes by 69%, improved quality of life beyond clinically meaningful thresholds, and was well tolerated with no treatment‐related serious adverse events. ABSTRACT Background Treatment options for medically‐
Adil E. Bharucha, Ramesh Lamichhane, Joel G. Fletcher, Nicholas R. Oblizajek, Misha Gautam, Kent R. Bailey, Lawrence A. Szarka   +6 more
wiley   +1 more source

Effects of Special Milk Powder for Gastrointestinal Tract Conditioning on Intestinal Motility and Microflora Composition in Constipation Mice

Shipin gongye ke-ji, 2022
Objective: To study the effect of special milk powder for gastrointestinal tract conditioning on intestinal bowel and intestinal microflora. Methods: After the preparation of special milk powder for gastrointestinal tract conditioning, KM mice were used ...
Hezhixiang XU, Xiaojun YANG, Dixin SHA, Wuxiuer MEDINA   +3 more
doaj   +1 more source

Chemical Profiles, Pharmacological Insights, and In Silico Studies of Antidesma montanum Blume: An Experimental and Computer‐Aided Approach

eFood, Volume 7, Issue 4, August 2026.
Antidesma montanum, an edible wild plant, shows notable nutraceutical and pharmacological potential. Methanol extract profiling (GC–MS) identified bioactive metabolites. In vitro, in vivo, and in silico studies demonstrated significant antidiabetic, anthelmintic, anxiolytic, antidepressant, and antidiarrheal activities, supported by strong molecular ...
Naureen Banu, Najmul Alam, Sadia Farid Jhuma, Mohammad Nazmul Islam, Shady A. Alghazali, Md Abdul Awal, Sanjida Islam, Hafsa Siddiqua, Shafinaz Nur, Md. Sohel Rana   +9 more
wiley   +1 more source

Chaetocarpus castanocarpus Bark Extract Alleviates Pain, Pyrexia, Diarrhea, Hyperglycemia, and Oxidative Stress: Evidence From Integrated In Vitro and In Vivo Studies

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Graphical abstract illustrating Chaetocarpus castanocarpus bark extract alleviates pain, pyrexia, diarrhea, hyperglycemia, and oxidative stress: Evidence from integrated in vitro and in vivo studies. ABSTRACT There is a history of using the medicinal plant Chaetocarpus genus, native to Southeast Asia, to treat a wide range of illnesses.
Rakibur Rahman, Farjana Akter Nipa, Taimun Siddique, Tania Rahman, Abed Foyez Rafi, Alfesani, Ziaul Karim, Tuhin Chandra Das, Riniara Khatun, Abdur Rauf, Hassan A. Hemeg   +10 more
wiley   +1 more source

Loperamide [PDF]

Reactions Weekly, 2020
  +6 more sources

Loperamide [PDF]

Journal of Pain and Symptom Management, 2011
Claud, Regnard, Robert, Twycross, Mary, Mihalyo, Andrew, Wilcock   +3 more
openaire   +3 more sources

Identifying patient‐centered outcomes in progressive familial intrahepatic cholestasis: Results from IMPACT

Journal of Pediatric Gastroenterology and Nutrition, Volume 83, Issue 2, Page 215-222, August 2026.
Abstract Objectives In rare diseases like progressive familial intrahepatic cholestasis (PFIC), lack of evidence results in treatment variability and strategies for families to engage care teams to understand how variability affects overall health are unknown.
James E. Squires, Gitta H. Lubke, Emily Ventura, Alexandra Perez, Paula M. Hertel, Emily R. Perito, Laura Bull, Melissa Kochanowsky   +7 more
wiley   +1 more source

Loperamide increases mouse gut transit time in a dose-dependent manner with treatment duration-dependent effects on distinct gut microbial taxa

Gut Microbiome
Intestinal transit time has been recognized as an important factor in shaping the gut microbiota, although causality remains to be firmly demonstrated. The aim of this study was to evaluate the effect of different loperamide doses on the mouse intestinal
Anna Pii Hjørne, Martin Steen Mortensen, Tine Rask Licht, Martin Frederik Laursen   +3 more
doaj   +1 more source

A case report on the long‐term use of teduglutide in a pediatric patient with short bowel syndrome

Nutrition in Clinical Practice, Volume 41, Issue 4, Page 1253-1259, August 2026.
Abstract Short bowel syndrome (SBS) is the leading cause of intestinal failure, frequently necessitating long‐term parenteral nutrition (PN). Teduglutide (TED), a glucagon‐like peptide‐2 analog, has demonstrated efficacy in reducing PN dependence in both adults and children. However, long‐term data in pediatric populations remain limited.
Tsuyoshi Sakurai, Hironori Kudo, Nakamura Megumi, Ryo Ando, Takuro Kazama, Ryuji Okubo, Masatoshi Hashimoto, Ko Minoshima, Motoshi Wada   +8 more
wiley   +1 more source

Medication Burden: Beyond Counts to Recognize Polypharmacy as an Inherent Part of Living With Chronic Kidney Disease

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 2, August 2026.
ABSTRACT Medication burden in older patients with chronic kidney disease (CKD) is substantial, and simple medication counts are insufficient for identifying those at elevated risk of inappropriate prescribing. This study characterized medication burden by assessing the number of medications, potentially inappropriate medications (PIMs) and ...
Morten Baltzer Houlind, Helle Gybel Juul‐Larsen, Charlotte Strandhave, Niels Westergaard, Anne Estrup Olesen   +4 more
wiley   +1 more source