Results 51 to 60 of about 11,037 (196)

Expert Consensus on the Combined Application of Radiotherapy and Novel Systemic Agents in Breast Cancer Treatment

Journal of Evidence-Based Medicine, EarlyView.
ABSTRACT The rapid advancement of radiotherapy techniques and systemic anticancer agents has created unprecedented opportunities to improve outcomes for breast cancer patients, while also introducing new challenges related to optimal integration and safety.
Jie Lan, Wenyi Zhou, Qiufan Zheng, Lu Cao, Wenyan Chen, Zhenyu He, Chunling Jiang, Yanchu Li, Wen Xia, Huihua Xiong, Xiaoli Yu, Jun Zhang, Jianli Zhao, Yanxia Zhao, Lei Liu, Xin Wu, Shusen Wang, Xiaobo Huang, Jing Jing   +18 more
wiley   +1 more source

Final findings from the CONTROL trial: Strategies to reduce the incidence and severity of neratinib-associated diarrhea in patients with HER2-positive early-stage breast cancer

Breast, 2023
Background: Neratinib is an irreversible pan-HER tyrosine kinase inhibitor approved for HER2-positive early-stage and metastatic breast cancer. Diarrhea is the most frequent side effect and the most common reason for early discontinuation.
Arlene Chan, Manuel Ruiz-Borrego, Gavin Marx, A. Jo Chien, Hope S. Rugo, Adam Brufsky, Michael Thirlwell, Maureen Trudeau, Ron Bose, José A. García-Sáenz, Daniel Egle, Barbara Pistilli, Johanna Wassermann, Kerry A. Cheong, Benjamin Schnappauf, Dieter Semsek, Christian F. Singer, Navid Foruzan, Daniel DiPrimeo, Leanne McCulloch, Sara A. Hurvitz, Carlos H. Barcenas   +21 more
doaj   +1 more source

Novel and emerging antimicrobial strategies in the management of oral infections

Periodontology 2000, EarlyView.
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley   +1 more source

Increase of plasma corticosterone induced by loperamide in rats.

, 1982
Loperamide given intracerebroventricularly and intraperitoneally to rats provoked, like morphine, a plasma corticosterone increase 60 min after injection.
Gori E., PAROLARO, DANIELA, R. Senini, Giagnoni G, D. Parolaro, E. Gori, G. Giagnoni, M. Sala, L. Marabini, Sala M, Marabini L, Senini R   +11 more
core   +1 more source

Ocrelizumab‐induced colitis: VigiBase disproportionality analysis, case reports and literature review

British Journal of Clinical Pharmacology, Volume 92, Issue 7, Page 2162-2170, July 2026.
Aims Ocrelizumab is a humanized anti‐CD20 monoclonal antibody used in multiple sclerosis. Since its commercialization, several cases of ocrelizumab‐induced colitis have been reported in the scientific literature. Methods To explore the potential association of ocrelizumab with colitis as an adverse drug reaction (ADR), we conducted a descriptive and ...
Audrey Fresse, Christophe Hommel, Nadine Petitpain, Philippe Kerschen   +3 more
wiley   +1 more source

Naloxone does not prevent the conduction blockade effects of loperamide.

, 2013
The nerve was preincubated with naloxone (4 µg/10 µl) for 5 minutes followd by incubation with loperamide (5 µg/10 µl for 10 min).
Yun Guan (36851), Michael Tal (314337), Srinivasa N. Raja (314343), Matthias Ringkamp (253465), Alvin McKelvy (314339), Richard A. Meyer (253504), Matthew Wooten (314338), Timothy V. Hartke (253485), Brian P. Turnquist (314342)   +8 more
core   +1 more source

Loperamide [PDF]

Journal of Pain and Symptom Management, 2011
Claud, Regnard, Robert, Twycross, Mary, Mihalyo, Andrew, Wilcock   +3 more
openaire   +3 more sources

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1787-1808, June 2026.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Systematic review of loperamide : No proof of antibiotics being superior to loperamide in treatment of mild/moderate travellers' diarrhoea

, 2016
Looking at the worldwide emergency of antimicrobial resistance, international travellers appear to have a central role in spreading the bacteria across the globe.
Laaveri, Tinja,, Kantele, Anu,, Rombo, Lars,, Kantele, Anu, Laaveri, T, Sterne, J, Sterne, Jesper, Rombo, L, Rombo, Lars, Sterne, Jesper,, Kantele, A, Laaveri, Tinja   +11 more
core   +1 more source

Loperamide increases mouse gut transit time in a dose-dependent manner with treatment duration-dependent effects on distinct gut microbial taxa

Gut Microbiome
Intestinal transit time has been recognized as an important factor in shaping the gut microbiota, although causality remains to be firmly demonstrated. The aim of this study was to evaluate the effect of different loperamide doses on the mouse intestinal
Anna Pii Hjørne, Martin Steen Mortensen, Tine Rask Licht, Martin Frederik Laursen   +3 more
doaj   +1 more source