Results 21 to 30 of about 9,440 (158)

Quantitative proteomic analysis reveals the effects of mu opioid agonists on HT22 cells

open access: yesFrontiers in Pharmacology, 2023
Introduction: At present, the mu opioid receptor is the most important neuroaesthetics receptor in anesthesiology research, and the damage that it does to the nervous system is unknown.Methods: We investigated the effects of loperamide, an agonist of the
Xutong Zhang   +4 more
doaj   +1 more source

A life-threatening ventricular arrhythmia secondary to loperamide abuse, “a poor man’s methadone”

open access: yesHeart Vessels and Transplantation, 2021
The case of a patient with repetitive syncope episodes with a history of using loperamide at high doses for recreational purposes in search of an effect similar to heroin, is reported.
Miguel A. Rojas Carrera   +3 more
doaj   +1 more source

Comparative Analysis of Quality Requirements for Loperamide Hydrochloride Medicinal Products

open access: yesРегуляторные исследования и экспертиза лекарственных средств
INTRODUCTION. Loperamide hydrochloride medicinal products are registered in the Russian Federation in the dosage forms of “tablets” and “capsules”. Since the State Pharmacopoeia of the Russian Federation (SP RF) does not include pharmacopoeial articles ...
A. N. Novichenko   +3 more
doaj   +1 more source

Left Ventricular Regional Wall Motion Abnormality in the Setting of Acute Loperamide Overdose

open access: yesClinical Practice and Cases in Emergency Medicine, 2019
Loperamide is an inexpensive, over-the-counter antidiarrheal agent with emerging reports of overdose due to its opioid properties. Although it is considered by many patients to be safe, cardiotoxicity has been reported, prompting the United States Food ...
Kasha Bornstein   +2 more
doaj   +1 more source

Case Report: Pancreatic Paraganglioma Mimicking a Well‐Differentiated Neuroendocrine Tumor: The Importance of Cytokeratin Immunohistochemistry

open access: yesDiagnostic Cytopathology, EarlyView.
ABSTRACT Paragangliomas (PGLs) are uncommon neuroendocrine tumors most commonly found in the head and neck that originate from neural crest cells. Primary pancreatic paraganglioma is exceedingly rare and has largely been described in case reports and small case series. We present the case of a 79‐year‐old woman with an incidental pancreatic head lesion
Tanner Storozuk, Marc Vecchio
wiley   +1 more source

Loperamide-Induced Ventricular Tachycardia Storm

open access: yesAvicenna Journal of Medicine, 2022
Loperamide is an over-the-counter antilaxative medication with minor opioid properties. For this reason, it has recently become a drug of concern for the Food and Drug Administration due to its potential for abuse.
William Giesing   +4 more
doaj   +1 more source

Evaluation of the acceptance rate of analgesic stewardship team recommendations at a metropolitan hospital network

open access: yesJournal of Pharmacy Practice and Research, EarlyView.
Abstract Background Analgesic stewardship (AGS) programs, a novel concept in Australia, aim to assess and optimise opioid and other analgesia by carrying out medication reviews and providing clinical recommendations to the treating teams. Aim This study aimed to determine the rate and extent of acceptance of AGS team recommendations among adult ...
Hatsumi Kobayashi   +4 more
wiley   +1 more source

Biological activities and bioactive constituents of Flammulina velutipes: An updated systematic review

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract Flammulina velutipes (enokitake) is an edible mushroom recognized for both its nutritional and medicinal properties. It exhibits a broad spectrum of biological activities, including antioxidant, anti‐inflammatory, antitumor, immunomodulatory, and gut microbiota‐regulating effects.
Rıdvan Özgen   +2 more
wiley   +1 more source

Prebiotics/Probiotics Mixture Induced Changes in Cecal Microbiome and Intestinal Morphology Alleviated the Loperamide-Induced Constipation in Rat

open access: yesFood Science of Animal Resources, 2021
The aim of this study was to investigate the effect of a mixture of multi-strain probiotics and prebiotics on loperamide-induced constipation in Sprague-Dawley rats.
Min Guk Kim   +5 more
doaj   +1 more source

Risk of Cardiac Lesion with Chronic and Acute Use of Loperamide—An Integrative Review

open access: yesJournal of Cardiovascular Development and Disease, 2022
Loperamide is a synthetic opioid commonly used as an antidiarrheal due to its activation of u-opioid receptors in the myenteric plexus. In therapeutic doses, it inhibits peristalsis and has anti-secretory and anti-motility effects, until metabolized by ...
Bruna Cremonezi Lammoglia   +9 more
doaj   +1 more source

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