A Systematic Review of therapeutic agents for the treatment of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) [PDF]
, 2019 Background The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) was first described in 2012 and attracted a great international attention due to multiple healthcare associated outbreaks.
Al-Ali, Anfal Y. +2 more
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‘ Loperamide overdose induces ventricular tachycardia with catastrophic outcomes’
Journal of Community Hospital Internal Medicine Perspectives, 2020 Loperamide is a widely available, over-the-counter medication. The advent of the opioid epidemic has seen cases of loperamide overdose being reported. The common side effects of the medication can be relatively benign, but at high doses, loperamide can ...
Zain Ali +4 more
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Loperamide cases reported to United States poison centers, 2010–2022
Injury Epidemiology, 2023 Background Intentional use of high doses of loperamide has been linked to serious cardiac toxicity. The objective of this study is to investigate the characteristics and trends of loperamide cases reported to United States (US) poison centers and to ...
Aaditya Patel +7 more
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An opioid-like system regulating feeding behavior in C. elegans [PDF]
, 2015 Neuropeptides are essential for the regulation of appetite. Here we show that neuropeptides could regulate feeding in mutants that lack neurotransmission from the motor neurons that stimulate feeding muscles. We identified nlp-24 by an RNAi screen of 115
Artyukhin, Alexander B. +3 more
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Fecal incontinence: the quality of reported randomized, controlled trials in the last ten years. [PDF]
, 2008 This study was designed to analyze the characteristics and the quality of reporting of randomized, controlled trials published during the last ten years on fecal ...
Chelvanayagam, Sonya +2 more
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Antidiarrheal action of Zataria multiflora hydroalcoholic and hexane extracts in mice [PDF]
, 2017 Introduction: Zataria multiflora Boiss. is an indigenous herbal plant found in many parts of Iran. This herb is traditionally used as a remedy for treating gastrointestinal disorders including diarrhea.
Asghari, Gholamreza. +2 more
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Racecadotril for acute diarrhoea in children: systematic review and meta-analyses [PDF]
, 2015 OBJECTIVE Racecadotril is an antisecretory agent that can prevent fluid/electrolyte depletion from the bowel as a result of acute diarrhoea, without affecting intestinal motility. An up-to-date systematic review is indicated to summarise the evidence on
Alam +31 more
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Loperamide Induced Life Threatening Ventricular Arrhythmia
Case Reports in Cardiology, 2016 Loperamide is over-the-counter antidiarrheal agent acting on peripherally located μ opioid receptors. It is gaining popularity among drug abusers as opioid substitute. We report a case of a 46-year-old male that was presented after cardiac arrest.
Ankit Upadhyay +6 more
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Journal of Pharmacological Sciences, 2005 The effect of loperamide on tachykinin NK2- and NK3-receptor-mediated 5-HT outflow from guinea pig colonic mucosa was investigated in vitro. The selective tachykinin NK2-receptor agonist [β-Ala8]-neurokinin A4–10 (βAla-NKA) or the selective NK3-receptor ...
Shu-ichi Kojima +2 more
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Quantitative proteomic analysis reveals the effects of mu opioid agonists on HT22 cells
Frontiers in Pharmacology, 2023 Introduction: At present, the mu opioid receptor is the most important neuroaesthetics receptor in anesthesiology research, and the damage that it does to the nervous system is unknown.Methods: We investigated the effects of loperamide, an agonist of the
Xutong Zhang +4 more
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