Results 121 to 130 of about 23,058 (301)

Expert Consensus on Real‐World Use of Trofinetide for Rett Syndrome Using a Modified Delphi Method

Annals of the Child Neurology Society, Volume 4, Issue 1, Page 38-51, March 2026.
ABSTRACT Objective Trofinetide is the first approved treatment for Rett syndrome (RTT) in the United States and Canada. Trofinetide improved the core symptoms of RTT in clinical trials, and real‐world evidence supports the findings of clinical trials.
Erin O'Connor Prange, Arthur Beisang, Davut Pehlivan, Bernhard Suter, Paula Schleifer   +4 more
wiley   +1 more source

Ginseng Volatile Oil Alleviates Loperamide‐Induced Constipation in Mice by Regulating the Microbiota/Metabolism/Neural Network

Food Frontiers, Volume 7, Issue 2, March 2026.
GVO relieves constipation mechanisms. GVO decreased the abundance of Firmicutes and increased that of Bacteroidota, thereby ameliorating Lop‐induced gut microbial imbalances. Then the level of 8,9‐DiHETrE was raised, whereas the level of 15(S)‐HpETE was lowered.
Yanan Xu, Mingyue Wang, Meixin Chen, Zhilong Wang, Baoyue Zhang, Xin Wang, Liying Shang, Lequn Zhang, Bowen Sui, Wei Zhang, Jingzhou Zhang, Xueyuan Bai   +11 more
wiley   +1 more source

A Review of the Role of Melatonin in Irritable Bowel Syndrome [PDF]

, 2014
Irritable bowel syndrome (IBS) is a troubling disease experienced worldwide. The presentation of symptoms varies from patient to patient, and current prescription treatments can be inadequate in resolving symptoms.
Brinn, Nicole R., Gandhi, Mona A.
core   +1 more source

The Anti‐Constipation Effect of Garlic Polysaccharides: Roles of Gut Barrier Integrity, VIP Pathway, and the Microbiota‐SCFAs Axis

Food Science &Nutrition, Volume 14, Issue 3, March 2026.
Garlic polysaccharides (GP) demonstrated potential against functional constipation. In vitro, GP exhibited digestive resistance properties and boosted beneficial Bifidobacterium and Lactobacillus. In constipated mice, GP alleviated constipation by reducing oxidative stress and repairing the mechanical, chemical, and immune barriers.
Jingfang Li, Jiaxin Miao, Tianyi Li, Chanyuan Xie, Wentao Xu, Shimin Chang, Ran Chai   +6 more
wiley   +1 more source

Loperamide abuse [PDF]

Canadian Medical Association Journal, 2017
Tony, Antoniou, David N, Juurlink
openaire   +2 more sources

Towards the Continuous Manufacturing of Liquisolid Tablets Containing Simethicone and Loperamide Hydrochloride with the Use of a Twin-Screw Granulator [PDF]

, 2023
Daniel Żakowiecki, Margarethe Richter, Ceren Yuece, Annika Voelp, Maximilian Ries, Markos Papaioannou, Peter Edinger, Tobias Heß, Krystyna Mojsiewicz‐Pieńkowska, Krzysztof Cal   +9 more
openalex   +1 more source

Loperamide Dependence: A Case Report [PDF]

Addiction and Health, 2017
Background: Loperamide is used as an antidiarrheal drug and is available over-the-counter. It cannot pass the blood-brain barrier and it does not have a considerable abuse potential.
Mehran Zarghami, Maryam Rezapour
doaj  

Efficacy of Filgotinib for Treating Chronic Antibiotic‐Dependent Pouchitis: A Pilot Study

JCC Plus, Volume 1, Issue 2, March 2026.
Chronic pouchitis after restorative proctocolectomy for ulcerative colitis is often difficult to treat. This study evaluated the efficacy of filgotinib for patients with chronic pouchitis. Some patients with chronic pouchitis may be controlled with filgotinib.
Motoi Uchino, Yuki Horio, Ryuichi Kuwahara, Kurando Kusunoki, Kentaro Nagano, Kazunori Nomura, Yusuke Tomoo, Kozo Kataoka, Kei Kimura, Jihyung Song, Ayako Imada, Kazuma Ito, Yuko Fukumoto, Mizuki Koba, Masataka Ikeda, Hiroki Ikeuchi   +15 more
wiley   +1 more source

Differences in the Effectiveness of Uridine and Liriope platyphylla L. Between Complement Component 3 Deficiency- and Loperamide-Induced Constipation May Be Associated with the Alternative Regulation of the Cyclic Adenosine Monophosphate Downstream Signaling Pathway

Pharmaceuticals
Background/Objectives: Constipation can be induced in animal models through various factors such as loperamide (Lop) or complement component 3 (C3) deficiency.
Hee Jin Song, Eun Seo Park, Ji Eun Kim, Ayun Seol, Su Jeong Lim, Su Ha Wang, Ye Ryeong Kim, Ye Eun Ryu, So Hae Park, Jumin Park, Hyun Gu Kang, Dae Youn Hwang   +11 more
doaj   +1 more source

Flow Cytometry Role in Unlocking New Frontiers for Nanomedicine Applications of Plant‐Derived Vesicles

Journal of Extracellular Biology, Volume 5, Issue 3, March 2026.
ABSTRACT Extracellular vesicles (EVs) are nanoscale membrane‐bound vesicles released by any cell type under both physiological and pathological conditions. They carry a wide array of bioactive molecules, including microRNAs (miRNAs), lipids, proteins and other small biomolecules, and therefore play a key role in intercellular communication by ...
Tamer Esmail, Sabino Porro, Francesca D'Ascanio, Domenico De Bellis, Arianna Aquilini‐Mummolo, Giulia Colasante, Pasquale Simeone, Ayesha Younas, Marwa Balaha, Mariagiulia Filoso, Luana D'Onofrio, Melania Dovizio, Eleonora Aruffo, Piero Di Carlo, Lorenzo Secondi, Federica Flamminii, Tiziana Pietrangelo, Chiara Porro, Patrizia Ballerini, Angelo Cichelli, Paola Lanuti   +20 more
wiley   +1 more source