Results 161 to 170 of about 31,541 (206)
Model‐based approach to dose optimization of lopinavir/ritonavir when co‐administered with rifampicin [PDF]
British Journal of Clinical Pharmacology, 2012 WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT: Doubling the dose of lopinavir/ritonavir overcomes the effect of rifampicin on lopinavir concentrations. However, lopinavir concentrations are highly variable and side effects occur commonly.
Paolo Denti +2 more
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Lopinavir/Ritonavir in Pregnancy
JAIDS Journal of Acquired Immune Deficiency Syndromes, 2009The Antiretroviral Pregnancy Registry was established in 1989 to collect data on birth defects after pregnancy exposures to antiretroviral therapy. Using Registry data, this study estimates the birth defect risk after pregnancy exposures to lopinavir/ritonavir.The analysis population includes all prospective lopinavir/ritonavir-exposed pregnancies ...
Susan S, Roberts +5 more
openaire +2 more sources
The Annals of Pharmacotherapy, 2002
OBJECTIVE: To review the pharmacology, virology, pharmacokinetics, efficacy, safety, and clinical use of lopinavir/ritonavir (Kaletra, Abbott Laboratories). DATA SOURCES: English-language MEDLINE and AIDSline searches were performed ...
Amanda H, Corbett +2 more
openaire +2 more sources
OBJECTIVE: To review the pharmacology, virology, pharmacokinetics, efficacy, safety, and clinical use of lopinavir/ritonavir (Kaletra, Abbott Laboratories). DATA SOURCES: English-language MEDLINE and AIDSline searches were performed ...
Amanda H, Corbett +2 more
openaire +2 more sources
Lopinavir-NO, a nitric oxide-releasing HIV protease inhibitor, suppresses the growth of melanoma cells in vitro and in vivo [PDF]
Investigational New Drugs, 2019 We generated a nitric oxide (NO)-releasing derivative of the anti-HIV protease inhibitor lopinavir by linking the NO moiety to the parental drug. We investigated the effects of lopinavir and its derivative lopinavir-NO on melanoma cell lines in vitro and
Svetlana Paskaš +2 more
exaly +2 more sources
Journal of the Association of Nurses in AIDS Care, 2001
Treatment Review is intended to inform and update nurses about treatments relevant to HIV/AIDS. Product information presented in this column does not imply endorsement by the Association of Nurses in AIDS Care.
openaire +2 more sources
Treatment Review is intended to inform and update nurses about treatments relevant to HIV/AIDS. Product information presented in this column does not imply endorsement by the Association of Nurses in AIDS Care.
openaire +2 more sources
Monotherapy with lopinavir/ritonavir
Expert Opinion on Investigational Drugs, 2007Despite the unprecedented pace of development of drugs for the treatment of a viral disease and the unquestionable efficacy of antiretroviral therapy, there is a need for less toxic and cheaper regimens that could simplify the treatment of HIV infection without sacrificing efficacy.
Mauro, Schechter +1 more
openaire +2 more sources