Results 51 to 60 of about 3,037 (201)

Mutations in pre-core and basal-core promoter regions of hepatitis B virus in chronic HBV patients from Golestan, Iran [PDF]

open access: yes, 2014
Objective(s): It has been reported that the mutation of the pre-core (PC) and basal-core promoter (BCP) may play an important role in the development of HBV-related hepatocellular carcinoma (HCC).
Bazouri, M.   +5 more
core   +2 more sources

Métodos para a avaliação da hiperalgesia induzida por opioides no período perioperatório [PDF]

open access: yes, 2014
BACKGROUND AND OBJECTIVES: Opioid-induced hyperalgesia is a topic not yet fully understood in terms of mechanisms, diagnosis, prevention and treatment. Thus, it seems of great importance to evaluate this phenomenon that negatively affects the treatment ...
Leal, Plínio da Cunha   +1 more
core   +1 more source

Cutaneous Pseudolymphoma Following Administration of Lornoxicam

open access: yesActa Dermato-Venereologica, 2007
Since aspirin was introduced over a century ago, many new anti-inflammatory agents have been marketed. NSAIDs are currently the most commonly prescribed agents in Western medicine (1). Their widespread use has resulted in a number of well-documented adverse reactions. These most frequently involve the gastro-intestinal tract, causing discomfort, nausea
Stavrianeas, N.G.   +7 more
openaire   +3 more sources

Real‐World Characterization of Psychiatric Pharmacogenomic Test Ordering and Clinical Relevance in Adults and Children

open access: yesClinical and Translational Science, Volume 18, Issue 10, October 2025.
ABSTRACT Pharmacogenomic (PGx) testing is increasingly utilized to guide psychiatric medication selection and dosing, yet real‐world characterizations of test ordering and clinical implications remain understudied. Additionally, the extent to which psychiatry‐focused PGx results inform prescribing beyond mental health medications is unclear. This study
Lusi Zhang   +10 more
wiley   +1 more source

DutchHatTrick: semantic query modeling, ConText, section detection, and match score maximization [PDF]

open access: yes, 2011
This report discusses the collaborative work of the ErasmusMC, University of Twente, and the University of Amsterdam on the TREC 2011 Medical track. Here, the task is to retrieve patient visits from the University of Pittsburgh NLP Repository for 35 ...
Meij, Edgar   +2 more
core   +1 more source

Differential effects of left/right neuropathy on rats’ anxiety and cognitive behavior [PDF]

open access: yes, 2012
Chronic pain is frequently accompanied by a deterioration of emotional behavior and cognitive function. A small number of studies in humans concluded that pain-associated negative affect is more pronounced when pain is localized in the left side of the
Almeida, Armando   +7 more
core   +1 more source

Prevalence of Actionable Pharmacogenetic Genotype Frequencies, Cautionary Medication Use, and Polypharmacy in Community‐Dwelling Older Adults

open access: yesClinical Pharmacology &Therapeutics, Volume 118, Issue 2, Page 337-342, August 2025.
Older adults (65 years and over) frequently manage complex medication regimens and are vulnerable to adverse drug reactions and treatment inefficacies, some of which could be preventable with pharmacogenetics (PGx)‐guided prescribing. This study examined the prevalence of actionable PGx genotypes (i.e., those linked to a guideline that recommends a ...
Chad A. Bousman   +14 more
wiley   +1 more source

Comparison between lornoxicam quick-release and parecoxib for post-operative analgesia after laparoscopic cholecystectomy: A prospective randomized, placebo-controlled trial

open access: yesJournal of Anaesthesiology Clinical Pharmacology, 2013
Background: Non-steroidal anti-inflammatory drugs (NSAIDs) are valuable for post-operative pain as they reduce the use of opioids. Cyclooxygenase-2 inhibitors and traditional NSAIDs can be used. This is a prospective, randomized, placebo-controlled trial
Irene Kouroukli   +5 more
doaj   +1 more source

Electrochemical study of simple coumarin and its determination in aqueous infusion of Mikania glomerata [PDF]

open access: yes, 2014
The present study aims the development and application of an electrochemical method for simple coumarin determination in aqueous media by using a boron-doped diamond electrode (BDDE).
Codognoto, Lucia   +5 more
core   +2 more sources

Growing Interest in Pharmaceutical Cocrystals: A Comprehensive Review of Applications and Trends

open access: yesChemistrySelect, Volume 10, Issue 30, August 8, 2025.
Cocrystallization of an Active Pharmaceutical Ingredient (API) with a suitable coformer enables the development of multicomponent crystalline systems through green, cost‐effective methods. These cocrystals can enhance key physicochemical and biopharmaceutical properties. Abstract The synthesis of cocrystals stands as a promising and compelling strategy
Sandra Barbosa Neder Agostini   +3 more
wiley   +1 more source

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