Results 61 to 70 of about 1,888 (198)

ROS‐Responsive Thioketal–Mesoporous Silica Nanoparticles Codelivering Saikosaponin D Suppress Colorectal Cancer Liver Metastasis by Boosting Antitumor Immunity

Journal of Nanotechnology, Volume 2026, Issue 1, 2026.
Background Colorectal cancer (CRC) often metastasizes to the liver, which complicates treatment strategies. This study evaluates MSN–TK@SA, a mesoporous silica nanoparticle (MSN) loaded with saikosaponin D (SA) and reactive oxygen species (ROS)–cleaving thioketal (TK), as a targeted approach for CRC metastasis.
Xiaoxia Tang, Jinbao Chen, Shu Zhang, Jiaqi Huang, Hui Liu, Xiao Wang, Liulin Li, Yangcheng Li, Manli Xie, Munmun Bardhan   +9 more
wiley   +1 more source

Development and Characterization of Lornoxicam-Infused Ocular Gel for Effective Treatment of Ocular Inflammation in Domestic Cats

The Iraqi Journal of Veterinary Medicine
Lornoxicam (LOX) is a non-steroidal anti-inflammatory drug (NSAID) effective in managing ocular inflammation. Traditional delivery methods like liquid drops are cleared rapidly and may not provide sustained therapeutic levels, necessitating the ...
Riyam S Jafer, Hanan J Kassab
doaj   +1 more source

Formulation and characterization of solid lipid nanoparticles, nanostructured lipid carriers and nanoemulsion of lornoxicam for transdermal delivery

Acta Pharmaceutica, 2015
Solid lipid nanoparticles (SLN), nanostructured lipid carriers (NLC) and nanoemulsion (NE) of lornoxicam (LRX) were prepared for the treatment of painful and inflammatory conditions of the skin.
Gönüllü Ümit, Üner Melike, Yener Gülgün, Karaman Ecem Fatma, Aydoğmuş Zeynep   +4 more
doaj   +1 more source

POST-STROKE PAIN SYNDROMES: CLINICAL ASPECTS, DIAGNOSTIC CRITERIA, FEATURES OF THERAPY AND REHABILITATION MEASURES

Медицинский совет, 2017
The article is devoted to the topical problem of post-stroke pain syndromes, which are a frequent complication after a stroke. Pain after a stroke is associated with psychoemotional disorders, cognitive dysfunction, dysfunction, impaired quality of life ...
E. V. Kostenko
doaj   +1 more source

A pharmacokinetic interaction between cimetidine or ranitidine and lornoxicam [PDF]

Postgraduate Medical Journal, 1993
Summary Cimetidine 400 mg twice daily significantly increased serum concentrations and reduced apparent oral clearance of lornoxicam 8 mg twice daily in 12 healthy volunteers. Ranitidine 150 mg twice daily produced no significant changes in lornoxicam pharmacokinetics.
M, Ravic, I, Salas-Herrera, A, Johnston, P, Turner, K, Foley, D E, Rosenow   +5 more
openaire   +2 more sources

Model fitting of the lornoxicam reservoir patches (F1-F9) release profile.

, 2020
Model fitting of the lornoxicam reservoir patches (F1-F9) release profile.
Muhammad Harris Shoaib (5706638), Durriya Hashmat (8501499), Fatima Ramzan Ali (8501502), Fahad Siddiqui (8501505)   +3 more
core   +1 more source

Use of Drugs With Actionable Pharmacogenetic Biomarkers and Possible Prescribing Changes Among Older People

Journal of the American Geriatrics Society, Volume 73, Issue 12, Page 3679-3689, December 2025.
This graphical abstract illustrates the annual prevalence of exposure to CPIC Level A drugs among older adults, categorized by type of pharmacogenetic recommendation. Data are presented per 1000 older individuals (A) and per 1000 prescriptions (B).
Zinan Zhao, Yuxuan Zhao, Xiaowen Hu, Xue Wang, Gengchen Wang, Xinyi Zhang, Wenliang Dong, Luwen Shi, Xiaodong Guan, Christine Y. Lu, Pengfei Jin, Xiaoyan Nie   +11 more
wiley   +1 more source

Real‐World Characterization of Psychiatric Pharmacogenomic Test Ordering and Clinical Relevance in Adults and Children

Clinical and Translational Science, Volume 18, Issue 10, October 2025.
ABSTRACT Pharmacogenomic (PGx) testing is increasingly utilized to guide psychiatric medication selection and dosing, yet real‐world characterizations of test ordering and clinical implications remain understudied. Additionally, the extent to which psychiatry‐focused PGx results inform prescribing beyond mental health medications is unclear. This study
Lusi Zhang, Anthony J. Tholkes, Kaliya C. Jones, Laylia J. Yang, Gretchen K. Sieger, Kathryn R. Cullen, Meredith L. Gunlicks‐Stoessel, Pawel Mroz, Joel F. Farley, Steven G. Johnson, Jeffrey R. Bishop   +10 more
wiley   +1 more source

Comparison of different postoperative paın managements in patients submitted to transperitoneal laparoscopic renal and adrenal surgery

International Brazilian Journal of Urology, 2015
Purpose:We compared the effects of local levobupivacaine infiltration, intravenous paracetamol, intravenous lornoxicam treatments on postoperative analgesia in patients submitted to transperitoneal laparoscopic renal and adrenal surgery.Materials and ...
Altug Tuncel, Melih Balci, Aysun Postaci, Yilmaz Aslan, Ali Atan   +4 more
doaj   +1 more source

Neck pain as the problem of our time

Медицинский совет, 2020
During life, neck pain occurs in 20-70% of people, its prevalence in the total population is 4.9%, and the annual morbidity varies from 30 to 70%. Neck pain significantly reduces the quality of life and can lead to disability.
V. A. Golovacheva, A. A. Golovacheva, O. E. Zinovyeva   +2 more
doaj   +1 more source