Results 71 to 80 of about 1,888 (198)

Analgesic effects of platelet‐rich fibrin (PRF): A systematic review

open access: yesPeriodontology 2000, Volume 99, Issue 1, Page 132-184, October 2025.
Abstract Background Platelet‐rich fibrin (PRF), a second‐generation autologous platelet concentrate, has gained significant interest for its anti‐inflammatory and regenerative characteristics. While its role in tissue healing is well‐recognized, the analgesic potential of PRF remains under‐investigated.
Nathan E. Estrin   +6 more
wiley   +1 more source

Prevalence of Actionable Pharmacogenetic Genotype Frequencies, Cautionary Medication Use, and Polypharmacy in Community‐Dwelling Older Adults

open access: yesClinical Pharmacology &Therapeutics, Volume 118, Issue 2, Page 337-342, August 2025.
Older adults (65 years and over) frequently manage complex medication regimens and are vulnerable to adverse drug reactions and treatment inefficacies, some of which could be preventable with pharmacogenetics (PGx)‐guided prescribing. This study examined the prevalence of actionable PGx genotypes (i.e., those linked to a guideline that recommends a ...
Chad A. Bousman   +14 more
wiley   +1 more source

Growing Interest in Pharmaceutical Cocrystals: A Comprehensive Review of Applications and Trends

open access: yesChemistrySelect, Volume 10, Issue 30, August 8, 2025.
Cocrystallization of an Active Pharmaceutical Ingredient (API) with a suitable coformer enables the development of multicomponent crystalline systems through green, cost‐effective methods. These cocrystals can enhance key physicochemical and biopharmaceutical properties. Abstract The synthesis of cocrystals stands as a promising and compelling strategy
Sandra Barbosa Neder Agostini   +3 more
wiley   +1 more source

Questionable role of opioids for analgesia in renal colic and its urological interventions

open access: yesBJUI Compass, Volume 6, Issue 6, June 2025.
Abstract Objectives To review the different analgesic modalities and benefits of non‐opioid pain management options as well as their evidence‐based, established superiority, compared to opioid medications. Materials We review the updated literature about pain management of renal colic, a prevalent and painful urologic condition.
Anna Krieger   +4 more
wiley   +1 more source

EFFECT OF pH, SELECTED CYCLODEXTRINS AND COMPLEXATION METHODS ON THE SOLUBILITY OF LORNOXICAM [PDF]

open access: yes, 2014
Objective: The objective of the present study is to investigate the effect of pH, selected cyclodextrins and methods of complexation on the solubility of lornoxicam.
Gupta, V. Ram Mohan   +3 more
core   +1 more source

Liposome‐Based Interventions in Knee Osteoarthritis

open access: yesSmall, Volume 21, Issue 17, April 28, 2025.
Liposomes offer new opportunities for the management of knee osteoarthritis (OA). This review examines the last decade's advances, focusing on intra‐articularly (IA) administered liposomes and liposome‐based systems as pharmaceutical carriers and lubricants, while discussing their in vivo efficacy. Functionalized liposomes (with polymers, peptides etc.)
Evgenia Mitsou, Jacob Klein
wiley   +1 more source

Effect of lornoxicam on inflammatory markers in patients with non-ST-segment elevation acute coronary syndrome

open access: yesТерапевтический архив, 2010
Aim. To evaluate the clinical efficacy, safety, and effects of the nonsteroidal anti-inflammatory drug lornoxicam on inflammatory markers in non-ST-segment elevation acute coronary syndrome (NSTEACS). Subjects and methods.
Nikita Valer'evich Lomakin   +3 more
doaj  

Ten‐year analgesic utilization patterns and economic implications in Portugal

open access: yesBritish Journal of Clinical Pharmacology, Volume 91, Issue 3, Page 866-881, March 2025.
Abstract Aims This study evaluated the 10‐year consumption and economic patterns of classical analgesics, adjuvants and opioids in Portugal (2012‐2022), and conducted a comparative analysis between Portugal, Spain and Denmark to explore the consumption patterns among these countries for 2022.
Nuno Duarte   +3 more
wiley   +1 more source

Lornoxicam: a Newer NSAID

open access: yesIndian Journal of Physical Medicine & Rehabilitation, 2009
Pain relieving drugs are one of the most commonly useddrugs worldwide either through prescription or as overthe counter medication. Non-steroidal anti-inflammatorydrugs usually abbreviated as NSAIDs, are the drugs withanalgesic, antipyretic and, in higher doses, with antiinflammatoryeffects. NSAIDs inhibit cyclooxygenase(COX) 1 and 2.
Byrav PDS   +4 more
openaire   +1 more source

Development and Validation of a RP-HPLC-PDA method for Simultaneous Determination of Lornoxicam and Thiocolchicoside in Pharmaceutical dosage form and its Application for Dissolution study

open access: yesInternational Journal of Research in Pharmaceutical Sciences, 2011
A simple, selective, rapid, and precise RP-HPLC-PDA method has been developed for the simultaneous estimation of Lornoxicam (LOR) and Thiocolchicoside (THIO) in pharmaceutical dosage form by reverse phase liquid chromatography using Waters Symmetry C18 ...
Madhusmita Sahoo   +7 more
doaj  

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