Results 51 to 60 of about 1,649 (205)

Pharmacogenomic Calling From Whole‐Exome Sequencing in the Taiwanese Population—A Real‐World Experience

Molecular Genetics &Genomic Medicine, Volume 14, Issue 1, January 2026.
This study evaluated pharmacogenomic (PGx) calling from whole‐exome sequencing (WES) in 3562 Taiwanese individuals. Fourteen pharmacogenes were reliably identified, with each person carrying an average of ~2.4 actionable phenotypes. The high actionable frequencies of G6PD deficiency and HLA‐B*58:01 highlight ethnic differences and support WES as a ...
Hsu‐Heng Lin, Meng‐Ju Melody Tsai, Hui‐An Chen, Rai‐Hseng Hsu, Yun‐Syuan Lin, Yi‐Lin Lin, Ching Hsu, Yin‐Hsiu Chien, Wuh‐Liang Hwu, Ni‐Chung Lee   +9 more
wiley   +1 more source

Comparison between lornoxicam quick-release and parecoxib for post-operative analgesia after laparoscopic cholecystectomy: A prospective randomized, placebo-controlled trial

Journal of Anaesthesiology Clinical Pharmacology, 2013
Background: Non-steroidal anti-inflammatory drugs (NSAIDs) are valuable for post-operative pain as they reduce the use of opioids. Cyclooxygenase-2 inhibitors and traditional NSAIDs can be used. This is a prospective, randomized, placebo-controlled trial
Irene Kouroukli, Vasilios Zompolas, Vasiliki Tsekoura, Ioannis Papazoglou, Antonis Louizos, Venetiana Panaretou   +5 more
doaj   +1 more source

Formulation and evaluation of orodispersible tablets of lornoxicam

, 2018
Orodispersible tablets (ODTs), also known as fast melt, quick melts, fast disintegrating have the unique property of disintegrating in the mouth in seconds without chewing and the need of water.
Ansari, K Kareemuddin, Sharma, Neeraj
core   +1 more source

French‐Speaking Network of Pharmacogenetics (RNPGx) Recommendations for Gene Panel Analysis Through Genotyping or Sequencing in Pharmacogenetics

Fundamental &Clinical Pharmacology, Volume 40, Issue 1, January 2026.
ABSTRACT Background The implementation of pharmacogenetics in clinical practice increasingly relies on multigene panels. Objectives The objective of this study is to develop harmonized recommendations for the design and analytical implementation of multigene pharmacogenetic panels, defining clinically relevant genes and associated regions of interest ...
Nicolas Picard, Estelle Ayme‐Dietrich, Sylvie Quaranta, Tiphaine Adam‐De‐Beaumais, Abd El Kader Ait Tayeb, Hugo Alarcan, Dorra Amor, David Barthelemy, Mouna Ben Sassi, Séverine Cunat, Mouna Daldoul, Hervé Delacour, Marie‐Christine Etienne‐Grimaldi, Xavier Fonrose, Benjamin Hennart, Louis Lebreton, Stephanie Malard, Céline Narjoz, Asma Omezzine, Nicolas Pallet, Léa Payen, Jeanne Petit, Fabienne Thomas, Sameh Trabelsi, Camille Tron, Céline Verstuyft, Paul Vilquin, Jean‐Christophe Boyer, Vincent Haufroid, French‐Speaking Network of Pharmacogenetics (RNPGx)   +29 more
wiley   +1 more source

Organotin‐Drug Interactions. Organotin Adducts of Lornoxicam, Synthesis and Characterisation of the First Complexes of Lornoxicam

European Journal of Inorganic Chemistry, 2003
AbstractThe synthesis and spectral characterisation of novel organotin complexes [SnMe2(lorn)] (1) and [SnBu2(lorn)] (2) of the potent and widely used anti‐inflammatory drug lornoxicam, H2lorn, are reported. Crystal structure determinations of complexes1 and 2 showed that the ligand is doubly deprotonated at the oxygen and amide nitrogen atoms and is ...
Angeliki Galani, Mavroudis A. Demertzis, Maciej Kubicki, Dimitra Kovala‐Demertzi   +3 more
openaire   +3 more sources

Novel Screen-Printed Sensor with Chemically Deposited Boron-Doped Diamond Electrode: Preparation, Characterization, and Application

Biosensors, 2022
New screen-printed sensor with a boron-doped diamond working electrode (SP/BDDE) was fabricated using a large-area linear antenna microwave chemical deposition vapor system (LA-MWCVD) with a novel precursor composition.
Oleksandr Matvieiev, Renáta Šelešovská, Marian Vojs, Marián Marton, Pavol Michniak, Vojtěch Hrdlička, Michal Hatala, Lenka Janíková, Jaromíra Chýlková, Jana Skopalová, Petr Cankař, Tomáš Navrátil   +11 more
doaj   +1 more source

Biopolymer‐Based Encapsulation Approach: The Effect of Sea Buckthorn (Hippophae rhamnoides L.) Oil Carried by Chitosan on Fish Fillet Quality

Journal of Food Quality, Volume 2026, Issue 1, 2026.
In this study, the effects of chitosan (Ch) coatings encapsulated using an ultrasonic emulsification method with sea buckthorn (Hippophae rhamnoides L.) essential oil (HrEo) on the shelf life and quality parameters of rainbow trout (Oncorhynchus mykiss) fillets, in terms of microbiological, chemical, physical, and sensory properties, were investigated.
Gonca Alak, Ebrar Akpınar, Ayşe Kara, Muhammed Alaeddin Ekiz, Koray Koşar, Eylül Ecrin Ekiz, Elif Zeynep Özçelik, Tuba Akbey, Hakan Mete, Göktuğ Gedikli, Emir Birkan Tan, Momin Momin, Muhammed Atamanalp, Sultan Zahiruddin   +13 more
wiley   +1 more source

Intoxication by Lornoxicam in Two Dogs

Acta Scientiae Veterinariae, 2016
Background: The indiscriminate use of drugs is routinely observed in the field of veterinary medicine. Nonsteroidal antiinflammatory drugs (NSAIDs) are the class of drugs that most commonly cause intoxication in pet animals. Lornoxicam, an NSAID, is a cyclooxygenase COX-1 and COX-2 inhibitor and is only recommended for human treatment.
Albuquerque, Alice Ribeiro Oliveira Lima, Veloso, Jéssica Fontes, Calazans, Ana Paula Fernandes, Carlos, Renata Santiago Alberto   +3 more
openaire   +3 more sources

ROS‐Responsive Thioketal–Mesoporous Silica Nanoparticles Codelivering Saikosaponin D Suppress Colorectal Cancer Liver Metastasis by Boosting Antitumor Immunity

Journal of Nanotechnology, Volume 2026, Issue 1, 2026.
Background Colorectal cancer (CRC) often metastasizes to the liver, which complicates treatment strategies. This study evaluates MSN–TK@SA, a mesoporous silica nanoparticle (MSN) loaded with saikosaponin D (SA) and reactive oxygen species (ROS)–cleaving thioketal (TK), as a targeted approach for CRC metastasis.
Xiaoxia Tang, Jinbao Chen, Shu Zhang, Jiaqi Huang, Hui Liu, Xiao Wang, Liulin Li, Yangcheng Li, Manli Xie, Munmun Bardhan   +9 more
wiley   +1 more source

Use of Drugs With Actionable Pharmacogenetic Biomarkers and Possible Prescribing Changes Among Older People

Journal of the American Geriatrics Society, Volume 73, Issue 12, Page 3679-3689, December 2025.
This graphical abstract illustrates the annual prevalence of exposure to CPIC Level A drugs among older adults, categorized by type of pharmacogenetic recommendation. Data are presented per 1000 older individuals (A) and per 1000 prescriptions (B).
Zinan Zhao, Yuxuan Zhao, Xiaowen Hu, Xue Wang, Gengchen Wang, Xinyi Zhang, Wenliang Dong, Luwen Shi, Xiaodong Guan, Christine Y. Lu, Pengfei Jin, Xiaoyan Nie   +11 more
wiley   +1 more source