Neck pain as the problem of our time
During life, neck pain occurs in 20-70% of people, its prevalence in the total population is 4.9%, and the annual morbidity varies from 30 to 70%. Neck pain significantly reduces the quality of life and can lead to disability.
V. A. Golovacheva +2 more
doaj +1 more source
مقايسه بی دردی بعد از عمل در بيماران تحت عمل جراحی شکستگی ساق پا با تجويز پيش داروی سلکوکسيب در زمان های مختلف قبل از عمل جراحی [PDF]
زمينه و هدف: تجويز داروی سلکوکسيب خوراکی قبل از عمل جراحی به منظور پيشگيری از درد پس از آن در مطالعات مختلف به اثبات رسيده است. مطالعات مختلفی نيز در مورد دوز کافی و موثر جهت کنترل درد پس از عمل به انجام رسيده ولی در مورد تجويز تک دوز آن يا تجويز در ...
خلدبرین, علی رضا +4 more
core
Effect of Opioids vs NSAIDs and Larger vs Smaller Chest Tube Size on Pain Control and Pleurodesis Efficacy Among Patients With Malignant Pleural Effusion: The TIME1 Randomized Clinical Trial [PDF]
IMPORTANCE For treatment of malignant pleural effusion, nonsteroidal anti-inflammatory drugs (NSAIDs) are avoided because they may reduce pleurodesis efficacy.
Ali, N +32 more
core +2 more sources
A pharmacokinetic interaction between cimetidine or ranitidine and lornoxicam [PDF]
Summary Cimetidine 400 mg twice daily significantly increased serum concentrations and reduced apparent oral clearance of lornoxicam 8 mg twice daily in 12 healthy volunteers. Ranitidine 150 mg twice daily produced no significant changes in lornoxicam pharmacokinetics.
M, Ravic +5 more
openaire +2 more sources
Solid lipid nanoparticles (SLN), nanostructured lipid carriers (NLC) and nanoemulsion (NE) of lornoxicam (LRX) were prepared for the treatment of painful and inflammatory conditions of the skin.
Gönüllü Ümit +4 more
doaj +1 more source
Agrimonia eupatoria: atividade farmacológica, interações perigosas e efeitos colaterais. [PDF]
Nos últimos anos observa-se, a nível mundial, um aumento considerável no consumo de plantas medicinais. Segundo dados da Organização Mundial de Saúde (2002), cerca de 80% da população mundial utiliza produtos de origem natural para combater vários ...
Ribeiro, Maria Isabel
core
Older adults (65 years and over) frequently manage complex medication regimens and are vulnerable to adverse drug reactions and treatment inefficacies, some of which could be preventable with pharmacogenetics (PGx)‐guided prescribing. This study examined the prevalence of actionable PGx genotypes (i.e., those linked to a guideline that recommends a ...
Chad A. Bousman +14 more
wiley +1 more source
Influence of the Component Excipients on the Quality and Functionality of a Transdermal Film Formulation [PDF]
The influence of formulation variables, i.e., a hydrophilic polymer (Methocel® E15) and a film-forming polymer (Eudragit® RL 100 and Eudragit® RS 100), on the physicochemical and functional properties of a transdermal film formulation was assessed ...
Atram, Sandip C. +5 more
core +1 more source
Targeting the inflammation-related molecules with nonsteroidal anti-inflammatory drugs (NSAIDs) represents a promising approach for cancer prevention/therapy.
Lyubomir Marinov +6 more
semanticscholar +1 more source
Growing Interest in Pharmaceutical Cocrystals: A Comprehensive Review of Applications and Trends
Cocrystallization of an Active Pharmaceutical Ingredient (API) with a suitable coformer enables the development of multicomponent crystalline systems through green, cost‐effective methods. These cocrystals can enhance key physicochemical and biopharmaceutical properties. Abstract The synthesis of cocrystals stands as a promising and compelling strategy
Sandra Barbosa Neder Agostini +3 more
wiley +1 more source

