Results 41 to 50 of about 27,872 (253)
Advanced Science, EarlyView.This study demonstrates that polyC‐RNA‐binding protein 1 (PCBP1) in ventral hippocampal astrocytes modulates depressive‐like behaviors by regulating glutathione peroxidase 4‐mediated ferroptosis and synaptic glutamatergic transmission. PCBP1 overexpression intervention in the chronic unpredictable mild stress model rescues behavioral deficits ...
Jinyu Zhang +15 more
wiley +1 more source
On the descriptive value of loss aversion in decisions under risk: Six clarifications [PDF]
Judgment and Decision Making, 2013 Previous studies of loss aversion in decisions under risk have led to mixed results. Losses appear to loom larger than gains in some settings, but not in others.
Eyal Ert, Ido Erev
doaj +3 more sources
Is loss-aversion magnitude-dependent? Measuring prospective affective judgments regarding gains and losses [PDF]
Judgment and Decision Making, 2017 Prospect Theory proposed that the (dis)utility of losses is always more than gains due to a phenomena called ‘loss-aversion’, a result obtained in multiple later studies over the years.
Sumitava Mukherjee +3 more
doaj
Hungry for Knowledge: Octopamine Signaling Regulates Hunger‐Enhanced Olfactory Learning
Advanced Science, EarlyView.Researchers demonstrate that hunger state facilitates both aversive and appetitive olfactory learning. Two distinct octopamine signaling pathways are involved in aversive or appetitive memory formation in the hunger state. And, hunger state also facilitates the formation of both types of memories via an evolutionarily conserved norepinephrine (the ...
Huijuan Zhao +14 more
wiley +1 more source
Reference-dependent preferences and loss aversion [PDF]
Judgment and Decision Making, 2008 This study employs a Discrete Choice Experiment (DCE) in the health-care sector to test the loss aversion theory that is derived from reference-dependent preferences: The absolute subjective value of a deviation from a reference point is generally ...
Einat Neuman, Shoshona Neuman
doaj
The Effect of Wealth Shocks on Loss Aversion: Behavior and Neural Correlates
Frontiers in Neuroscience, 2017 Kahneman and Tversky (1979) first demonstrated that when individuals decide whether or not to accept a gamble, potential losses receive more weight than possible gains in the decision. This phenomenon is referred to as loss aversion.
V. S. Chandrasekhar Pammi +7 more
doaj +1 more source
Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology
Advanced Science, EarlyView.Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto +11 more
wiley +1 more source
Judgment and Decision Making, 2008 This study employs a Discrete Choice Experiment (DCE) in the health-care sector to test the loss aversion theory that is derived from reference-dependent preferences: The absolute subjective value of a deviation from a reference point is generally ...
Einat Neuman, Shoshana Neuman
doaj +1 more source
Advanced Science, EarlyView.Psoriatic disease (PsD) is a chronic skin disease, with challenges in early risk stratification and drug development. Through gene‐level causal inference framework and expression level validation, combined with longitudinal cohort study, CDSN and PRSS8 have been identified as candidate biomarkers and therapeutic targets for PsD.
Tianxing Wu +13 more
wiley +1 more source
Advanced Science, EarlyView.Doehl et al. discovered an adaptive neuroimmune mechanism that induces itch in tick‐exposed guinea pigs, enabling rapid tick removal. This itch‐induced tick removal (IITR) is mediated by an adaptive cellular immune response and is independent of IgG, IgE, or TRPV1.
Johannes S. P. Doehl +27 more
wiley +1 more source