Results 111 to 120 of about 114,870 (312)

BEAM LOSS MONITORING AND MITIGATION AT J-PARC DTL [PDF]

open access: yes, 2020
In the J-PARC linac, we have observed significant residual radiation at the first tank of a 50 MeV drift tube linac (DTL). The residual radiation has been localized at a certain drift tube. It has motivated us to measure the beam loss at the DTL. Instead
J-Parc Center   +7 more
core  

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Interregional burden-sharing of greenhouse gas mitigation in the United States [PDF]

open access: yes
Emissions trading is an attractive candidate for implementing greenhouse gas mitigation, because it can promote both efficiency and equity. This paper analyzes the interregional impacts of alternative allocations of carbon dioxide emission permits within
Rose, Adam, Zhang, ZhongXiang
core   +1 more source

What Loss Mitigation Taught Us About Housing Finance Reform [PDF]

open access: yes, 2015
This blog post describes the implications of the recent US loss mitigation experience for housing ...
McCoy, Patricia A.
core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Climate Mitigation or Technological Revolution? A Critical Choice of Futures [PDF]

open access: yes
Mankind currently is not only facing a major environmental challenge, it is embarking on a hugely risky enterprise — that of climate mitigation. This unprecedented global adventure is an attempt to change the nature and shape of human society on the ...
Graeme Donald Snooks
core  

Towards Robust Exchanges: Evaluating Ecological Compensation in New Zealand [PDF]

open access: yes, 2014
Ecological compensation is commonly employed but rarely evaluated around the world. In order to assess application of the tool in New Zealand, a systematic nationwide review was undertaken.
Brown, Marie Amanda
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Investigating primate densities and human-primate conflict in Tembaro Community Conserved Forest, Omo River Basin, Ethiopia

open access: yesBMC Zoology
Background Human-primate conflict is a global conservation challenge, particularly in densely populated, low-income countries like Ethiopia. The Omo River Valley forest belt, spanning across the Omo River in Ethiopia to Lake Turkana in Kenya, harbors a ...
Meselech Anshebo   +2 more
doaj   +1 more source

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