Results 61 to 70 of about 114,870 (312)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Climate refugia implications of warming and land-intensive mitigation under overshoot
Environmental Research LettersBiodiversity loss is expected to escalate with every increment of global warming. Simultaneously, land-intensive climate change mitigation strategies, such as afforestation and bioenergy, may further compound biodiversity loss.
Ruben Prütz +17 more
doaj +1 more source
Preservation of Bile Ductules Mitigates Bile Duct Loss
American Journal of Transplantation, 2006 The finer branches of the biliary tree (FBBT) contain a regenerative compartment. We hypothesized that preservation of the FBBT together with its microvasculature will lead to recovery of biliary damage and prolonged preservation of bile ductules during the development of chronic liver allograft rejection.
van den Heuvel, M.C. +5 more
openaire +3 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Mitigation of interfacial dielectric loss in aluminum-on-silicon superconducting qubits
npj Quantum InformationWe demonstrate aluminum-on-silicon planar transmon qubits with time-averaged T 1 energy relaxation times of up to 270 μs, corresponding to Q = 5 million, and a highest observed value of 501 μs.
Janka Biznárová +11 more
doaj +1 more source
Bovine rabies: economic loss and its mitigation through antirabies vaccination
Pesquisa Veterinária Brasileira: Rabies is among the most common neurological disease in cattle in Brazil, causing significant economic losses. Data on the economic impact of rabies in livestock are available in several countries.
Ana Karla M. Mello +6 more
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
The Effect of Wetland Mitigation Banking on the Achievement of No-Net-Loss [PDF]
, 1999 This study determines whether the 68 wetland mitigation banks in existence in the United States through 1 January 1996 are achieving no-net-loss of wetland acreage nationally and regionally.
Brown, Phillip H., Lant, Christopher L.
core +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source