Results 71 to 80 of about 114,870 (312)
Reducing greenhouse gas emissions in agriculture without compromising food security?
Environmental Research Letters, 2017 To keep global warming possibly below 1.5 °C and mitigate adverse effects of climate change, agriculture, like all other sectors, will have to contribute to efforts in achieving net negative emissions by the end of the century.
Stefan Frank +13 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Benefit-Cost Analysis of FEMA Hazard Mitigation Grants [PDF]
Mitigation ameliorates the impact of natural hazards on communities by reducing loss of life and injury, property and environmental damage, and social and economic disruption.
John C. Whitehead +15 more
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Evaluation of the Iowa Department of Transportation's Compensatory Wetland Mitgation Program, August 30, 2004 [PDF]
, 2004 The purpose of this investigation was to evaluate the Compensatory Wetland Mitigation Program at the Iowa Department of Transportation (DOT) in terms of regulatory compliance.
core
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Loss functions for structural flood mitigation measures [PDF]
, 2004 The paper aims at discussing the methodology used to develop loss functions for flood mitigation measures, using historic data of flood damage to infrastructure.
Berning, C, Du Plessis, LA, Viljoen, MF
core +2 more sources
Homeowner mitigation decision‐making: Exploring the theory of planned behaviour approach
Journal of Flood Risk Management, 2020 During hurricanes, flooding and wind cause property damage and loss of life. Increased coastal development and recent economic impacts of hurricanes has increased stakeholders' interest in coastal mitigation.
Rachel Slotter +4 more
doaj +1 more source
Mechanism Analysis of Smart Cue on Aircraft for Loss of Control Mitigation
IEEE Access, 2020 This paper analyzes the mechanism of the smart inceptor on the aircraft, as a means to mitigate human-vehicle system loss-of-control. We divide the smart inceptor cue into three modes: the smart cue on the human pilot, the smart cue on the flight control
Shuting Xu, Zhe Zhang
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source