Results 261 to 270 of about 173,415,106 (290)

Loss of heterozygosity for chromosome 14q in neuroblastoma

Medical and Pediatric Oncology, 2001
Neuroblastoma is a genetically heterogeneous disease, with subsets of tumors demonstrating rearrangements of several genomic regions. Preliminary studies from several groups have identified loss of heterozygosity (LOH) for the long arm of chromosome 14 (14q) in 20-25% of primary neuroblastomas.To determine precisely the frequency and extent of 14q ...
P M, Thompson, B A, Seifried, S K, Kyemba, S J, Jensen, C, Guo, J M, Maris, G M, Brodeur, D O, Stram, R C, Seeger, R, Gerbing, K K, Matthay, T C, Matise, P S, White   +12 more
openaire   +2 more sources

Loss of heterozygosity analysis in malignant gliomas

Brain Tumor Pathology, 2011
Despite recent advances in the diagnosis and treatment of glioblastomas, patient outcomes for these highly malignant tumors remain poor. Research into the molecular pathology of glioblastoma has uncovered various genetic changes that contribute to malignancy.
Masahiro, Mizoguchi, Daisuke, Kuga, Yanlei, Guan, Nobuhiro, Hata, Akira, Nakamizo, Koji, Yoshimoto, Tomio, Sasaki   +6 more
openaire   +2 more sources

Frequent loss of heterozygosity at 6q in pheochromocytoma

Human Pathology, 2006
Multiple genetic alterations have been associated with pheochromocytoma (PCC). Most PCCs are sporadic, but they also occur in inherited tumor syndromes, including von Hippel-Lindau disease. Although the etiology of most inherited PCCs is well documented, little is known about the etiology of sporadic tumors.
Sebsebe, Lemeta, Kaisa, Salmenkivi, Lea, Pylkkänen, Markku, Sainio, Sirkku T, Saarikoski, Johanna, Arola, Päivi, Heikkilä, Caj, Haglund, Kirsti, Husgafvel-Pursiainen, Tom, Böhling   +9 more
openaire   +2 more sources

Loss of somatic heterozygosity in hepatocellular carcinoma.

Cancer research, 1991
Loss of tumor suppressor genes is involved in the mechanism of tumorigenesis of many solid tumors. We tested 9 hepatitis B virus (HBV)-positive and 10 HBV-negative hepatocellular carcinomas for loss of somatic heterozygosity using 14 polymorphic probes mapping to chromosomes 4, 11, 13, and 17. Losses were found on all chromosome arms tested.
Walker, Graeme J., Hayward, Nicholas K., Falvey, Scott, Cooksley, W. Graham E.   +3 more
openaire   +2 more sources

Loss of Heterozygosity

2013
Steven J. Frampton, Emma V. King
openaire   +2 more sources

Loss of heterozygosity in tertiary hyperparathyroidism

Transplantation Proceedings, 2002
E, Konya, H, Tsuji, N, Amasaki, T, Umekawa, M, Iguchi, T, Kurita   +5 more
openaire   +2 more sources

Loss of heterozygosity in laryngeal cancer.

Roczniki Akademii Medycznej w Bialymstoku (1995), 2005
Head and neck cancers account for about 6% of all human cancers. Molecular changes leading to the disease development and progression still remain not fully explained. Examination of loss of heterozygosity (allelic loss, LOH) using the specific microsatellite markers is a method of choice in assessing tumour suppressor genes (TSGs) localisation in ...
M, Rogowski, I, Walenczak, W, Pepiński, M, Skawrońska, A, Sieśkiewicz, J, Klatka   +5 more
openaire   +1 more source

Loss of Heterozygosity

2006
openaire   +2 more sources

Loss of Heterozygosity

2011
openaire   +2 more sources

Loss of heterozygosity (LOH) in ovarian cancer

International Journal of Gynecology & Obstetrics, 2004
C, Bozzetti, B, Bortesi, C, Merisio
openaire   +2 more sources