Results 141 to 150 of about 6,468,446 (336)
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Penerapan Sistem Mrp Untuk Pengendalian Persediaan Bahan Baku Animal Feedmill Dengan Lot Sizing Berdasarkan Algoritma Wagner-within Dan Silver-meal (Studikasus: PT. Sierad Produce, Tbk.) [PDF]
, 2014 PT.Sierad Produce, Tbk. merupakan Perusahaan Nasional yang memproduksi pakan ternak. Pengelolaanpersediaan menjadifokusutamapada PT. Sierad Produce, Tbk.
Prima, D. S. (Danny) +2 more
core +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
An Improved WAGNER-WHITIN Algorithm
International Journal of Industrial Engineering and Production Research, 2009 We present an improved implementation of the Wagner-Whitin algorithm for economic lot-sizing problems based on the planning-horizon theorem and the Economic- Part-Period concept.
S. J Sadjadi +2 more
doaj
The collaborative multi-level lot-sizing problem with cost synergies. [PDF]
Int J Prod Res, 2020 Gansterer M, Hartl RF.
europepmc +1 more source
Dynamic lot sizing with product returns [PDF]
, 2005 We address the dynamic lot sizing problem for systems with product returns. The demand and return amounts are deterministic over the finite planning horizon. Demands can be satisfied by manufactured/procured new items, but also by remanufactured returned
Bayindir, Z.P. (Pelin) +2 more
core
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Optimal selection of cotton warp sizing parameters under system research limitation
Sistemnì Doslìdženâ ta Informacìjnì TehnologìïWarp sizing is the process of applying the sizing agents to the warp yarn to improve its weavability along with improving the economic performance of weaving.
Hanna Tkachuk +2 more
doaj +1 more source
The linear dynamic lot size problem with minimum order quantities [PDF]
This paper continues the analysis of a special uncapacitated single item lot sizing problem where a minimum order quantity restriction, instead of the setup cost, guarantees a certain level of production lots.
Okhrin, Irena, Richter, Knut
core