Results 101 to 110 of about 31,024 (202)

Purification of Lovastatin from Aspergillus terreus (KM017963) and evaluation of its anticancer and antioxidant properties [PDF]

, 2016
Cervical cancer is the second most common malignancy in women worldwide and thus one of the leading causes of mortality in women. Lovastatin, a non polar, anticholesterol drug has previously been reported to exert antitumour activity in vitro.
Bhargavi, S., Marium, S., Praveen, V., Savitha, J., Sreepriya, M.   +4 more
core  

An In-Depth Examination of Formularies and Other Features of Medicare Drug Plans [PDF]

, 2006
Provides a detailed assessment of the formularies, drug costs, and utilization management tools offered by the fourteen nationwide organizations that account for most of the stand-alone prescription drug ...
Elizabeth Hargrave, Jack Hoadley, Juliette Cubanski, Tricia Neuman   +3 more
core  

Anti-proliferative and apoptotic effects of Lovastatin on K562 Erthromyloidy cancer cell line

مجله دانشگاه علوم پزشکی گرگان, 2017
Background and Objective: Lovastatin is a HMG-CoA reductase inhibitor and used for the treatment of hypercholesterolemia. Inhibition of HMG-CoA reductase results in inhibiting the activity of the Ras proto-oncogene that has mutations in most cancers ...
M Vaezi, M Mohammadzadeh, Y Pazhang
doaj  

The Role of Quorum Sensing in Enhancing Lovastatin and Pigment Production in Monascus purpureus C322

Fermentation
Monascus purpureus is a filamentous fungus known for producing pharmaceutically valuable secondary metabolites, including azaphilone pigments and lovastatin.
Sirisha Yerramalli, Stephen J. Getting, Godfrey Kyazze, Tajalli Keshavarz   +3 more
doaj   +1 more source

Lovastatin Reduces Stemness via Epigenetic Reprograming of BMP2 and GATA2 in Human Endometrium and Endometriosis

Cell Journal, 2017
Objective The stem cell theory in the endometriosis provides an advanced avenue of targeting these cells as a novel therapy to eliminate endometriosis.
Mehrdad Noruzinia, Mahdieh Taghizadeh
doaj  

Effect of Lovastatin on Learning and Spatial Memory in Adult Male Rats

Iranian South Medical Journal, 2018
Background: Previous studies have shown that statins exert neuroprotective effects. The aim of the present study was to evaluate the effects of lovastatin on learning and memory processes in adult male rats without brain damage. Materials and Methods: In
Azadeh Eskandary, Ahmad Ali Moazedi, Nastaran Zamani   +2 more
doaj  

Repurposing Simvastatin and Lovastatin for Colorectal Cancer: An Integrated in-Silico and in-Vitro Study

Natural Product Communications
Background Colorectal cancer (CRC) is a leading cause of cancer-related mortality worldwide. Statins, widely prescribed lipid-lowering agents, have been suggested to possess anticancer activity; however, their precise mechanisms in CRC remain poorly ...
Kavya Manjunath, Fady H. Fayek, Shaik Sadik, Sreeharsha Nagaraja, Santosh Prasad Chaudhary Kurmi, Shankar Thapa   +5 more
doaj   +1 more source

Therapy-induced cholesterol biosynthesis drives lung cancer dormancy and drug resistance. [PDF]

J Clin Invest
Zhao Y, Zhou Y, Pan L, Tian GG, Huang HY, Tang S, Lu M, Zhou Z, Zhang P, Chen L, Zhang L, Hu L, Ji H.   +12 more
europepmc   +1 more source

Squalene synthase induces ERα expression via cholesterol supplementation to confer statin resistance in lung cancer cells. [PDF]

Cancer Cell Int
Yang YF, Chang YC, Chan MH, Lin MH, Yang CJ, Huang MS, Jan YH, Hsiao M.   +7 more
europepmc   +1 more source

Development and Validation of an HPLC-MS/MS Method for Pharmacokinetic Evaluation of Tofacitinib/Simvastatin Compound Ointment in Rats. [PDF]

Drug Des Devel Ther
Wang S, Zhang C, Li J, Li G, Qi Y.
europepmc   +1 more source