Results 91 to 100 of about 31,024 (202)

Effects of lovastatin and dietary cholesterol on bile acid kinetics and bile lipid composition in healthy male subjects.

open access: yesJournal of Lipid Research, 1994
We measured bile acid kinetics and bile lipids in 12 human subjects on a metabolic ward in four randomly allocated, 6-7 week periods: 1) lovastatin (40 mg b.i.d) + low cholesterol diet (mean 246 mg/day); 2) lovastatin+high cholesterol diet (mean 1071 mg ...
W C Duane
doaj   +1 more source

Aspergillus westerdijkiae polyketide synthase gene “aoks1” is involved in the biosynthesis of ochratoxin A [PDF]

open access: yes, 2009
OchratoxinA (OTA) is a potential nephrotoxic, teratogenic, immunogenic, hepatotoxic and carcinogenic mycotoxin, produced by Aspergillus westerdijkiae NRRL 3174.
Atoui, Ali   +4 more
core   +2 more sources

Mood, Personality, and Behavior Changes During Treatment with Statins: A Case Series. [PDF]

open access: yes, 2015
Psychiatric adverse drug reactions (ADRs) have been reported with statin use, but the literature regarding statin-associated mood/behavioral changes remains limited.
Cham, Stephanie   +2 more
core   +1 more source

Lovastatin prevents bleomycin-induced DNA damage to HepG2 cells

open access: yesResearch in Pharmaceutical Sciences, 2016
Lovastatin as a member of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors is used as a lipid-lowering agent. It can also inhibit the formation of hydrogen peroxide and superoxide anion and finally leads to decline in oxidative stress
Marjan Nasiri   +3 more
doaj   +1 more source

The effects of Purslane (Portulaca oleracea L.) on serum level of lipids, lipoproteins and paraoxanase 1(PON1) activity in hypercholesterolemia patients [PDF]

open access: yes, 2012
Some unverified reports around the world demonstrated that Purslane has therapeutic effects on some conditions. The aim of this study was to compare the effects of Purslane and Lovastatin therapy in decreasing serum lipids, lipoproteins, and paraoxanase1
Farrokhi, Effat.   +4 more
core  

Solid State Fermentation: An Effective Method for Lovastatin Production by Fungi over Submerged Fermentation [PDF]

open access: yes, 2012
The Enzyme 3-hydroxy-3-methylglutaryl-CoA reductase (HMG CoA reductase) catalyses conversion of HMG CoA to mevalonate during cholesterol biosynthesis. Lovastatin is used as an anti-cholesterol drug which blocks HMG CoA reductase activity.
Praveen, V.K., Savitha, J.
core  

Altered apolipoprotein B metabolism in very low density lipoprotein from lovastatin-treated guinea pigs.

open access: yesJournal of Lipid Research, 1994
Previous studies have shown that treatment of guinea pigs with lovastatin alters the composition and the metabolic properties of circulating low density lipoprotein (LDL).
L F Berglund   +3 more
doaj   +1 more source

Resistance-gene-directed discovery of a natural-product herbicide with a new mode of action. [PDF]

open access: yes, 2018
Bioactive natural products have evolved to inhibit specific cellular targets and have served as lead molecules for health and agricultural applications for the past century1-3.
Bat-Erdene, Undramaa   +9 more
core  

Supercritical Fluid Extraction of Lovastatin from the Wheat Bran Obtained after Solid-State Fermentation

open access: yesFood Technology and Biotechnology, 2009
The objective of the present work is to extract lovastatin with minimum impurity by using supercritical carbon dioxide (SC-CO2). A strain of Aspergillus terreus UV 1617 was used to produce lovastatin by solid-state fermentation (SSF) on wheat bran as a ...
Ruchir C. Pansuriya, Rekha S. Singhal
doaj  

SAFETY EVALUATION OF STATIN IN YOGYAKARTA, INDONESIA [PDF]

open access: yes, 2009
Background : The 3-hydroxy-3-methylglutaryl-coenzyme (HMG-Co-A) reductase inhibitors, also known as statins, are the most effective class of drugs for lowering serum Low-Density Lipoprotein cholesterol (LDL-c)concentrations.
Anni, Anni   +3 more
core  

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