Results 91 to 100 of about 31,024 (202)
We measured bile acid kinetics and bile lipids in 12 human subjects on a metabolic ward in four randomly allocated, 6-7 week periods: 1) lovastatin (40 mg b.i.d) + low cholesterol diet (mean 246 mg/day); 2) lovastatin+high cholesterol diet (mean 1071 mg ...
W C Duane
doaj +1 more source
Aspergillus westerdijkiae polyketide synthase gene “aoks1” is involved in the biosynthesis of ochratoxin A [PDF]
OchratoxinA (OTA) is a potential nephrotoxic, teratogenic, immunogenic, hepatotoxic and carcinogenic mycotoxin, produced by Aspergillus westerdijkiae NRRL 3174.
Atoui, Ali +4 more
core +2 more sources
Mood, Personality, and Behavior Changes During Treatment with Statins: A Case Series. [PDF]
Psychiatric adverse drug reactions (ADRs) have been reported with statin use, but the literature regarding statin-associated mood/behavioral changes remains limited.
Cham, Stephanie +2 more
core +1 more source
Lovastatin prevents bleomycin-induced DNA damage to HepG2 cells
Lovastatin as a member of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors is used as a lipid-lowering agent. It can also inhibit the formation of hydrogen peroxide and superoxide anion and finally leads to decline in oxidative stress
Marjan Nasiri +3 more
doaj +1 more source
The effects of Purslane (Portulaca oleracea L.) on serum level of lipids, lipoproteins and paraoxanase 1(PON1) activity in hypercholesterolemia patients [PDF]
Some unverified reports around the world demonstrated that Purslane has therapeutic effects on some conditions. The aim of this study was to compare the effects of Purslane and Lovastatin therapy in decreasing serum lipids, lipoproteins, and paraoxanase1
Farrokhi, Effat. +4 more
core
Solid State Fermentation: An Effective Method for Lovastatin Production by Fungi over Submerged Fermentation [PDF]
The Enzyme 3-hydroxy-3-methylglutaryl-CoA reductase (HMG CoA reductase) catalyses conversion of HMG CoA to mevalonate during cholesterol biosynthesis. Lovastatin is used as an anti-cholesterol drug which blocks HMG CoA reductase activity.
Praveen, V.K., Savitha, J.
core
Previous studies have shown that treatment of guinea pigs with lovastatin alters the composition and the metabolic properties of circulating low density lipoprotein (LDL).
L F Berglund +3 more
doaj +1 more source
Resistance-gene-directed discovery of a natural-product herbicide with a new mode of action. [PDF]
Bioactive natural products have evolved to inhibit specific cellular targets and have served as lead molecules for health and agricultural applications for the past century1-3.
Bat-Erdene, Undramaa +9 more
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The objective of the present work is to extract lovastatin with minimum impurity by using supercritical carbon dioxide (SC-CO2). A strain of Aspergillus terreus UV 1617 was used to produce lovastatin by solid-state fermentation (SSF) on wheat bran as a ...
Ruchir C. Pansuriya, Rekha S. Singhal
doaj
SAFETY EVALUATION OF STATIN IN YOGYAKARTA, INDONESIA [PDF]
Background : The 3-hydroxy-3-methylglutaryl-coenzyme (HMG-Co-A) reductase inhibitors, also known as statins, are the most effective class of drugs for lowering serum Low-Density Lipoprotein cholesterol (LDL-c)concentrations.
Anni, Anni +3 more
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