Results 41 to 50 of about 317,672 (284)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
“Sevgili Şâhbâzıyla Gönül/Can Kuşu Avlamak” Hayali Üzerine
Uluslararası Uygur Araştırmaları Dergisi, 2019 Kadim zamanlarda kullanılan avlanma usulleri, edebî eserlerde sanat gayesiyle yer bulmuştur. Özellikle alıcı bir kuş olarak bilinen şahbazla yapılan avlar ve bu av sahnelerindeki usuller, şairlerin şiirlerinde kullandıkları albenisi yüksek birer sanat ...
Selim GÖK
doaj
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Opp som en løve og ned som en skinnfell – hvor er departementet?
Magma, 2020 Dette nummeret av Magma burde inneholdt en oppdatering av sentrale lover for oss økonomer. De siste årene har vi hatt fire sentrale lover opp til revurdering: aksjeloven, regnskapsloven, regnskapsførerloven og revisorloven.
Finn Kinserdal, Kjell Ove Røsok
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
, 2015 This documentary film, The Lover\u27s Cup is the story of a former Naval Officer from World War II, Dr. Phillip Trapp, who took Marines into the battle of Iwo Jima and lived to see the flag being raised on Mt. Suribachi.
Guin, Kimberlee Relyea
core +1 more source
Investing in Prevention or Paying for Recovery - Attitudes to Cyber Risk [PDF]
, 2019 The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.Broadly speaking an individual can invest time and effort to avoid becoming victim to a cyber attack and/or
A Cartwright +19 more
core +2 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Possessing Love’s Reasons: Or Why a Rationalist Lover Can Have a Normal Romantic Life
Ergo, An Open Access Journal of Philosophy, 2021 The rationalist lover accepts that whom she ought to love is whom she has most reason to love. She also accepts that the qualities of a person are reasons to love them.
Ting Cho Lau
doaj +2 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source