Results 71 to 80 of about 317,351 (287)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
“The country of his past”: Homecoming in “A Modern Lover” and “The Shades of Spring”
Études LawrenciennesIn the two early stories, “A Modern Lover” and “The Shades of Spring,” Lawrence imagines an autobiographical figure returning to his home country to renew connection with the young woman he had loved (a version of Jessie Chambers).
Keith Cushman
doaj +1 more source
Keakuratan Terjemahan Gaya Bahasa pada Novel Lady Chatterley’s Lover
Ranah: Jurnal Kajian Bahasa, 2018 Translating accuracy of source language into target language in a literary work require high appropriatness that retain the beauty of the language. The purpose of this study is to identify and describe level of accuracy of the translation in the figure ...
Nidya Pratiwi, M.R Nababan, NFN Djatmika
doaj +1 more source
Common Currency, Common Market? [PDF]
Does the common currency promote goods market integration within the EMU? We argue that such an effect is likely, but that the mechanism typically proposed – lover costs of arbitrage because of increased price transparency – is likely to be of minor ...
Richard Friberg
core
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
A of Political-Social Discourse Analysis of the Relationship between Lover and Beloved onein the lyric poems of Sa’di [PDF]
متن شناسی ادب فارسی, 2017 In romantic literature of Iraqi style, particularly in Sa’di’s lyric poems, the cruelty and oppression of the sweetheart and the degradation and contempt of the lover in front of her are proposed abundantly.
Alli Akbar Bagheri Khalili +1 more
doaj
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
ANTHROPOLOGICAL DESCRIPTION OF LOVE INTO MINSTREL TALES / HALK HİKÂYELERİNDEKİ AŞKIN ANTROPOLOJİK BETİMLEMESİ [PDF]
Folklor/Edebiyat, 2014 The subject of this study is love between man and women who in minstrel folk tales. Aim of the study is described the love narrated by minstrel tales. For this purpose, theories and models on love which based on ethnographic data and mainly developed ...
Çiğdem Kara
doaj