Expression of Low Affinity Nerve Growth Factor Receptor p75 in Classic Bladder Exstrophy [PDF]
Frontiers in Pediatrics, 2021 Successful primary closure of classic bladder exstrophy (BE) is crucial for development of bladder capacity and voided continence. It is universally agreed that an intensive pain management including the use of caudal epidural anesthesia is an essential ...
Martin Promm +9 more
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Age-Related Yield of Adipose-Derived Stem Cells Bearing the Low-Affinity Nerve Growth Factor Receptor [PDF]
Stem Cells International, 2013 Adipose-derived stem cells (ADSCs) are a heterogeneous cell population that may be enriched by positive selection with antibodies against the low-affinity nerve growth factor receptor (LNGFR or CD271), yielding a selective cell universe with higher ...
Raquel Cuevas-Diaz Duran +5 more
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Low-affinity Nerve Growth Factor Receptor (CD271) Heterogeneous Expression in Adult and Fetal Mesenchymal Stromal Cells. [PDF]
Sci Rep, 2018 AbstractHuman multipotent mesenchymal stromal cells (MSC) are isolated from a plethora of tissue sources for cell therapy purposes. In 2006, the International Society for Cellular Therapy (ISCT) published minimal guidelines to define MSC identity.
Barilani M +10 more
europepmc +7 more sources
Neurotrophin Receptor p75NTR Regulates Immune Function of Plasmacytoid Dendritic Cells [PDF]
Frontiers in Immunology, 2017 Plasmacytoid dendritic cells (pDCs) regulate innate and adaptive immunity. Neurotrophins and their receptors control the function of neuronal tissue. In addition, they have been demonstrated to be part of the immune response but little is known about the
Joanna Bandoła +19 more
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Characterization and Functional Analysis of CD44v6.CAR T Cells Endowed with a New Low-Affinity Nerve Growth Factor Receptor-Based Spacer. [PDF]
Hum Gene Ther, 2021 Stornaiuolo A +10 more
europepmc +2 more sources
Unveiling the Solvent Effect: DMSO Interaction with Human Nerve Growth Factor and Its Implications for Drug Discovery [PDF]
MoleculesBackground: The Nerve Growth Factor (NGF) is essential for neuronal survival and function and represents a key therapeutic target for pain and inflammation-related disorders, as well as for neurodegenerative diseases.
Francesca Paoletti +7 more
doaj +2 more sources
Current Oncology, 2022 Breast cancer represents the most common type of cancer and is the leading cause of death due to cancer among women. Thus, the prevention and early diagnosis of breast cancer is of primary urgency, as well as the development of new treatments able to ...
Francesco Bruno +5 more
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Identification of fibroblast growth factor receptor 3 (FGFR3) as a protein receptor for botulinum neurotoxin serotype A (BoNT/A). [PDF]
PLoS Pathogens, 2013 Botulinum neurotoxin serotype A (BoNT/A) causes transient muscle paralysis by entering motor nerve terminals (MNTs) where it cleaves the SNARE protein Synaptosomal-associated protein 25 (SNAP25206) to yield SNAP25197.
Birgitte P S Jacky +12 more
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Overexpression of p75NTR in Human Seminoma: A New Biomarker?
Life, 2021 Several studies have demonstrated that the p75NTR low-affinity receptor of Nerve Growth Factor (NGF), is produced in abnormally large amounts in several human cancer types.
Anna Perri +12 more
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Biomedicines, 2022 Neurotrophins are growth factors that exert important neuroprotective effects by preventing neuronal death and synaptic loss. Nerve Growth Factor (NGF) acts through the activation of its high-affinity, pro-survival TrkA and low-affinity, pro-apoptotic ...
Thanasis Rogdakis +15 more
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