Expression of Low Affinity Nerve Growth Factor Receptor p75 in Classic Bladder Exstrophy [PDF]
Successful primary closure of classic bladder exstrophy (BE) is crucial for development of bladder capacity and voided continence. It is universally agreed that an intensive pain management including the use of caudal epidural anesthesia is an essential ...
Martin Promm+9 more
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Age-Related Yield of Adipose-Derived Stem Cells Bearing the Low-Affinity Nerve Growth Factor Receptor [PDF]
Adipose-derived stem cells (ADSCs) are a heterogeneous cell population that may be enriched by positive selection with antibodies against the low-affinity nerve growth factor receptor (LNGFR or CD271), yielding a selective cell universe with higher ...
Raquel Cuevas-Diaz Duran+5 more
doaj +2 more sources
Low-affinity nerve-growth factor receptor (P75NTR) can serve as a receptor for rabies virus [PDF]
A random-primed cDNA expression library constructed from the mRNA of neuroblastoma cells (NG108) was used to clone a specific rabies virus (RV) receptor. A soluble form of the RV glycoprotein (Gs) was utilized as a ligand to detect positive cells. We identified the murine low-affinity nerve-growth factor receptor, p75NTR.
Christine Tuffereau
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Estrogen receptors colocalize with low-affinity nerve growth factor receptors in cholinergic neurons of the basal forebrain. [PDF]
The rodent and primate basal forebrain is a target of a family of endogenous peptide signaling molecules, the neurotrophins--nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3--and of the gonadal steroid hormone estrogen, both of which have been implicated in cholinergic function.
C. Dominique Toran‐Allerand+6 more
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Interaction of lyssaviruses with the low-affinity nerve-growth factor receptor p75NTR
The low-affinity nerve-growth factor receptor p75NTRinteractsin vitrowith the rabies virus (RV) glycoprotein and serves as a receptor for RV. TheLyssavirusgenus comprises seven genotypes (GTs) of rabies and rabies-related viruses. The ability of p75NTRto interact with the glycoprotein of representative lyssaviruses from each GT was investigated.
Christine Tuffereau+6 more
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Nerve growth factor stimulates MAPK via the low affinity receptor p75LNTR [PDF]
Apart from its high affinity receptor TrkA, nerve growth factor (NGF) can also stimulate the low affinity receptor p75LNTR and induce a Trk‐independent signaling cascade. We examined the possible involvement of mitogen‐activated protein kinase (MAPK) in this signaling pathway in neuronal cultures of the cerebellum of P2‐aged rats and PCNA cells; both ...
Kathrin Susen+2 more
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Localization of the low‐affinity nerve growth factor receptor p75 in human limbal epithelial cells [PDF]
AbstractBiological effects of nerve growth factor (NGF) are mediated through receptors known as nerve growth factor receptors (NGFR), which include p75 and TrkA. This study was initiated after identifying NGFR as an up‐regulated gene in the limbus by cDNA microarray analysis and we postulate that its expression may be indicative of a stem/progenitor ...
Nick Di Girolamo+5 more
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Involvement of a metalloprotease in low-affinity nerve growth factor receptor truncation: inhibition of truncation in vitro and in vivo [PDF]
The mechanism of low-affinity NGF receptor (LNGFR) truncation was investigated in cultured Schwann cells. Affinity labeling of Schwann cells with 125I-NGF or metabolic labeling with 35S-cysteine showed that truncated NGF receptor (NGF-Rt) was derived from the cell surface form of the receptor.
PS DiStefano+3 more
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Glycosyl-phosphatidylinositol/inositol phosphoglycan: a signaling system for the low-affinity nerve growth factor receptor. [PDF]
Nerve growth factor (NGF) exerts a variety of actions during embryonic development. At the early stages of inner ear development, NGF stimulates cell proliferation, an effect mediated through low-affinity receptors. We have studied the possibility that the glycosyl-phosphatidylinositol/inositol phosphoglycan (glycosyl-PtdIns/IPG) system is involved in ...
Juan Represa+7 more
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Hepatic Stellate Cells Express the Low Affinity Nerve Growth Factor Receptor p75 and Undergo Apoptosis in Response to Nerve Growth Factor Stimulation [PDF]
We have examined the expression of p75, a member of the TNF receptor superfamily in hepatic stellate cells (HSC) and pancreatic stellate cells (PSC). Activated HSC and PSC were demonstrated by Western blot analysis to express p75. p75 was immunolocalized to cells with a myofibroblast-like morphology in the fibrotic bands of six fibrotic and cirrhotic ...
Nathan Trim+7 more
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