Results 11 to 20 of about 91,338 (326)
Low-affinity nerve-growth factor receptor (P75NTR) can serve as a receptor for rabies virus [PDF]
The EMBO Journal, 1998 A random-primed cDNA expression library constructed from the mRNA of neuroblastoma cells (NG108) was used to clone a specific rabies virus (RV) receptor. A soluble form of the RV glycoprotein (Gs) was utilized as a ligand to detect positive cells. We identified the murine low-affinity nerve-growth factor receptor, p75NTR.
Christine Tuffereau
openalex +4 more sources
Nerve growth factor stimulates MAPK via the low affinity receptor p75LNTR [PDF]
FEBS Letters, 1999 Apart from its high affinity receptor TrkA, nerve growth factor (NGF) can also stimulate the low affinity receptor p75LNTR and induce a Trk‐independent signaling cascade. We examined the possible involvement of mitogen‐activated protein kinase (MAPK) in this signaling pathway in neuronal cultures of the cerebellum of P2‐aged rats and PCNA cells; both ...
Kathrin Susen +2 more
openalex +3 more sources
Neuroscience Letters, 1995 Northern blot, immunocytochemistry, and single nerve fiber immunostaining were used to determine the expression of low-affinity nerve growth factor (NGF) receptor (p75NGFR) in the peripheral nervous system of Lewis rats during the course of experimental allergic neuritis (EAN) induced with 100 micrograms of 'SP26' synthetic peptide, corresponding to ...
Giancarlo Conti +6 more
openalex +3 more sources
Effect of nerve growth factor and its transforming tyrosine kinase protein and low-affinity nerve growth factor receptors on apoptosis of notochordal cells [PDF]
International Orthopaedics, 2012 The disappearance of notochordal cells by apoptosis is thought to be the starting point of intervertebral disc degeneration. The aim of this study was to determine the apoptotic pathway of notochordal cells as well as the anti-apoptotic potential of caspase inhibitors.Rat notochordal cells were isolated, cultured, and placed in either 0 % (apoptosis ...
Kyung-Hwan Suhl +3 more
openalex +4 more sources
Cellular and Molecular Neurobiology, 1994 1. Antisense inhibition of gene expression implies that the expression of the target protein is selectively inhibited at either the translational or the transcriptional level by complementary DNA or RNA constructs that are antiparallel to the target sequence. The antisense inhibition strategy provides means to study the roles of individual proteins and
Kirsi Sainio +4 more
openalex +4 more sources
Localization of the low‐affinity nerve growth factor receptor p75 in human limbal epithelial cells [PDF]
Journal of Cellular and Molecular Medicine, 2008 AbstractBiological effects of nerve growth factor (NGF) are mediated through receptors known as nerve growth factor receptors (NGFR), which include p75 and TrkA. This study was initiated after identifying NGFR as an up‐regulated gene in the limbus by cDNA microarray analysis and we postulate that its expression may be indicative of a stem/progenitor ...
Nick Di Girolamo +5 more
openalex +3 more sources
Estrogen receptors colocalize with low-affinity nerve growth factor receptors in cholinergic neurons of the basal forebrain. [PDF]
Proceedings of the National Academy of Sciences, 1992 The rodent and primate basal forebrain is a target of a family of endogenous peptide signaling molecules, the neurotrophins--nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3--and of the gonadal steroid hormone estrogen, both of which have been implicated in cholinergic function.
C. Dominique Toran‐Allerand +6 more
openalex +4 more sources
POS0404 SOLUBLE LOW AFFINITY NERVE GROWTH FACTOR RECEPTOR (LNGFR) MAY REGULATE PAIN IN KNEE OSTEOARTHRITIS [PDF]
Annals of the Rheumatic Diseases, 2023 Ala Altaie +7 more
openalex +2 more sources
Nerve growth factor and its low-affinity receptor promote Schwann cell migration. [PDF]
Proceedings of the National Academy of Sciences, 1994 Migrating Schwann cells in developing or regenerating peripheral nerves are known to express dramatically increased levels of nerve growth factor (NGF) and the low-affinity NGF receptor (LNGFR). Schwann cells do not express detectable pp140trk, the NGF-activated receptor tyrosine kinase which is essential for neuronal responses to NGF.
E.S. Anton +3 more
openalex +3 more sources
Hepatic Stellate Cells Express the Low Affinity Nerve Growth Factor Receptor p75 and Undergo Apoptosis in Response to Nerve Growth Factor Stimulation [PDF]
The American Journal of Pathology, 2000 We have examined the expression of p75, a member of the TNF receptor superfamily in hepatic stellate cells (HSC) and pancreatic stellate cells (PSC). Activated HSC and PSC were demonstrated by Western blot analysis to express p75. p75 was immunolocalized to cells with a myofibroblast-like morphology in the fibrotic bands of six fibrotic and cirrhotic ...
Nathan Trim +7 more
openalex +4 more sources