Spectroscopic and chemical studies of the interaction between nerve growth factor (NGF) and the extracellular domain of the low affinity NGF receptor [PDF]
David E. Timm+3 more
openalex +1 more source
Type I Interferon Signaling Augments Autoimmunity in Neuromyelitis Optica Spectrum Disorder
The cGAS‐STING innate immune pathway is excessively activated both in peripheral monocytes and CNS microglia in patients with NMOSD, leading to an overproduction of IFN‐I. IFN‐I subsequently acts on AQP4‐specific autoreactive T cells. Blocking this pathway may offer novel therapeutic options for individuals with NMOSD.
Tian‐Xiang Zhang+13 more
wiley +1 more source
Exosomes: A Promising Cell-Free Therapeutic Tool for Treating Cutaneous Nerve Injuries and Promoting Wound Healing. [PDF]
Mu Y+7 more
europepmc +1 more source
BOTH THE LOW AND THE HIGH AFFINITY NERVE GROWTH FACTOR RECEPTORS (NGF-R) ARE EXPRESSED IN PANCREATIC BETA CELL LINES [PDF]
A. Tazi+4 more
openalex +1 more source
Peptide‐Based Biomaterials as a Promising Tool for Cancer Radiotherapy
This review provides a systematic overview of peptide‐based biomaterials in tumor radiotherapy, covering their roles as both radiosensitizers and radiopharmaceuticals. Peptide‐based radiosensitizers are generally divided into three categories: peptides as direct radiosensitizers, peptides as carriers of radiosensitizers, and targeted‐peptide‐modified ...
Qian Wang, Xinhui Chu, Jianfeng Liu
wiley +1 more source
Trigeminal nerve-driven neurogenic inflammation linking migraine to glioblastoma invasion: a literature review. [PDF]
Song X+5 more
europepmc +1 more source
This study presents a comprehensive data mining strategy for in‐depth extraction of overall and altered glycan features from structural and site‐specific glycoproteome data across various biomedical samples. The strategy enables the uncovery of four major altered glycan features associated with thymic involution and reveals their coordinated ...
Zhida Zhang+11 more
wiley +1 more source
Third-Generation Antipsychotics: The Quest for the Key to Neurotrophism. [PDF]
Mucci F+5 more
europepmc +1 more source
Activation of Kir4.1 Channels by 2‐D08 Promotes Myelin Repair in Multiple Sclerosis
Multiple sclerosis causes myelin loss and neurological dysfunction. This study shows that 2‐D08, a small molecule targeting Kir4.1 channels, promotes OPCs differentiation via FYN tyrosine kinase phosphorylation and the FYN/MYRF pathway. It significantly improves myelin repair and motor deficits in EAE mice and marmosets, highlighting its potential as a
Mingdong Liu+17 more
wiley +1 more source