Results 231 to 240 of about 139,660 (338)

Born to Fear the Machine? Genetic and Environmental Influences on Negative Attitudes toward AI Agents

Advanced Science, EarlyView.
Why do some people fear or distrust AI agents more than others? This twin study shows that negative attitudes toward AI may partly stem from genetic factors, linking them to traits like victim sensitivity and moral beliefs. These findings show that it is not only nurture but also nature that shapes our views of AI, with implications for future human–AI
Xiaojiayu Tan, Yue He, Yuan Zhou, Xinying Li, Qingwen Ding, Yikai Tang, Yu L. L. Luo, Ruolei Gu   +7 more
wiley   +1 more source

Effects of Stress and Allopregnanolone on the Expression of Neurotrophins and TrkB Receptor in the Sheep Hippocampus. [PDF]

Int J Mol Sci
Misztal T, Młotkowska P, Marciniak E, Barszcz M, Osuch B, Gajewska A, Misztal A.   +6 more
europepmc   +1 more source

Lesion-induced expression of low-affinity nerve growth factor receptor-immunoreactive protein in Purkinje cells of the adult rat

Neuroscience, 1993
R. Martínez‐Murillo, L. Caro, M. Nieto‐Sampedro   +2 more
semanticscholar   +1 more source

Contribution of Prostaglandin E2‐Induced Neuronal Excitation to Drug Resistance in Glioblastoma Countered by a Novel Blood–Brain Barrier Crossing Celecoxib Derivative

Advanced Science, EarlyView.
Glioblastoma (GBM) is an aggressive brain cancer that often recurs and resists chemotherapy. This study found that a chemical called PGE2 causes surrounding brain cells (neurons) to become over‐excited, which makes GBM cells resistant to treatment. Researchers developed a new drug, “Compound 11,” which can cross into the brain and effectively block ...
Chih‐Jie Shen, Hsien‐Chung Chen, Chien‐Liang Lin, Amandeep Thakur, Raphael Onuku, I‐Chung Chen, Hao‐Yi Li, Kwang‐Yu Chang, Jian‐Ying Chuang, Wen‐Bin Yang, Hong‐Yi Lin, Yi‐Ru Shen, Jing‐Ping Liou, Wen‐Chang Chang, Tsung‐I Hsu   +14 more
wiley   +1 more source

Spatiotemporal Adaptations‐Driven Dynamic Thra Activation Simulates a Skin Wound Healing Response

Advanced Science, EarlyView.
This study uncovers the thyroid hormone receptor Thra as a pivotal regulator that spatiotemporally orchestrates dual‐phase skin repair. Epidermal Thra accelerates barrier restoration via glutathione‐driven keratin assembly, while dermal Thra establishes angiogenic niches through SAA3‐FN1‐mediated matrix remodeling.
Zeming Li, Jiajun Tan, Chuqing Zhou, Siyi Zhou, Yuanli Ye, Xinzhu Li, Xinyu Shen, Tian Xie, Mengyue Wang, Jingwei Jiang, Yiping Zhao, Xiao Xiang, Yong Zhou, Jun Wu, Cheng‐Ming Chuong, Mingxing Lei   +15 more
wiley   +1 more source

Tumor-infiltrating nerves: unraveling the role of cancer neuroscience in tumorigenesis, disease progression, and emerging therapies. [PDF]

Discov Oncol
Wang X, Fan Y, Wang Q, Shu X, Lin J, Guo J, Li Z, Xu J.   +7 more
europepmc   +1 more source

A Novel Class of Multi‐substituted Diaryl Scaffold Derivatives Inhibit Glioblastoma Progression by Targeting CD155

Advanced Science, EarlyView.
Structural modification of clofoctol yielded a novel blood‐brain barrier‐permeable compound, B7, featuring a multi‐substituted diaryl scaffold. B7 demonstrates potent anti‐glioblastoma activity by suppressing glioblastoma stem cells proliferation, migration, and invasion through interactions with five key residues of poliovirus receptor cell adhesion ...
Yong‐jian Wang, Ting Sun, Si‐tu Xue, Zhong‐di Cai, Hong Yi, Miao Lv, Shi‐bo Kou, Rui Liu, Xiao‐zhong Peng, Zhuo‐rong Li   +9 more
wiley   +1 more source

Mast Cells at the Crossroads of Hypersensitivity Reactions and Neurogenic Inflammation. [PDF]

Int J Mol Sci
Aitella E, Romano C, Ginaldi L, Cozzolino D.   +3 more
europepmc   +1 more source

Achieving Complex Nanostructures: The Role of Hydrogen in Controlling Mechanical Alloying and Microstructure Evolution in the TiVZrNbHf‐Cu System

Advanced Science, EarlyView.
This study highlights the drastic influence hydrogen has on the microstructure evolution during severe plastic deformation. High‐pressure torsion of a TiVZrNbHf‐Cu composite results in mechanical alloying and subsequent amorphization, whereas replacing the high entropy alloy with the corresponding hydride stabilizes a two‐phase microstructure.
Lukas Schweiger, Florian Spieckermann, Peter Cengeri, Michael Burtscher, Lukas Schretter, Matthias Eichinger, Gregor Mori, Alexander Schökel, Michael Zehetbauer, Erhard Schafler, Daniel Kiener, Jürgen Eckert   +11 more
wiley   +1 more source

Serotonin neuromodulation directs optic nerve regeneration. [PDF]

Development
Saied-Santiago K, Baxter M, Mathiaparanam J, Granato M.   +3 more
europepmc   +1 more source