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Modulation of low‐affinity nerve growth factor receptor in injured adult rat spinal cord motoneurons

Journal of Comparative Neurology, 1993
AbstractSpinal and brainstem motoneurons of the adult rat reexpress low‐affinity nerve growth factor receptor (LNGFR) and its mRNA after axotomy. We have previously reported the time courses of this reexpression after cut (no regeneration) or crush (followed by regeneration) of the sciatic nerve. We have shown that the length of the different phases of
M, Rende, C, Provenzano, P, Tonali
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Characterization of the Glycosylation on Recombinant Human Low-Affinity Nerve Growth Factor Receptor

1992
Publisher Summary To study the structure of the nerve growth factor (NGF) binding region in this glycoprotein, a recombinant form (rhNGF-R) was prepared that contains the N-terminal 222 amino acids ending just before the transmembrane region of the native full length receptor. rhNGF-R is a soluble form of the receptor that retains its ability to bind
Christine A. Settineri   +5 more
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The expression of the low affinity nerve growth factor receptor in long-term denervated Schwann cells

Glia, 1997
Schwann cells in the distal stump of injured peripheral nerves synthesize the low affinity nerve growth factor receptor (p75). In this study we used short-term (1 week) and long-term (1-12 months) transected distal sciatic nerves of rats to determine the variations of p75 expression by using immunocytochemistry and in situ hybridization.
S, You, T, Petrov, P H, Chung, T, Gordon
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Expression of the Low-Affinity p75 Nerve Growth Factor Receptor in the Developing Rat Pituitary Gland

Neurochemical Research, 1997
We investigated, by means of in situ hybridization with a digoxigenin-labelled RNA probe, the expression of the low-affinity p75 nerve growth factor receptor (NGFR) in the developing pituitary primordium of the rat. In 13-day pc embryos, intense staining of p75 NGFR mRNA was present in the cytoplasm of all cells of Rathke's pouch.
D, Ramaekers, M, Proesmans, C, Denef
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Localization of trkB and low-affinity nerve growth factor receptor mRNA in the developing rat retina

Neuroscience Letters, 1995
The localization of trkB and low-affinity nerve growth factor receptor (LNGFR) mRNAs in the developing rat retina was examined by in situ hybridization. TrkB mRNA was expressed in the ganglion cell layer (GCL), in the inner border of the neuroblastic layer (NBL), and the inner border of the inner nuclear layer (INL). LNGFR mRNA was expressed in the GCL,
T, Koide   +6 more
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Localization of high-affinity and low-affinity nerve growth factor receptors in cultured rat basal forebrain

Neuroscience, 1988
Previous work has indicated that nerve growth factor specifically and selectively increases choline acetyltransferase and acetylcholinesterase in organotypic cultures of rat basal forebrain-medial septal area. To determine whether these actions are potentially receptor-mediated, organotypic and dissociated basal forebrain-medial septal area cultures ...
P, Bernd   +3 more
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Ciliary neurotrophic factor (CNTF) promotes low-affinity nerve growth factor receptor and CD4 expression by rat CNS microglia

Journal of Neuroimmunology, 1993
Ramified parenchymal microglia may provide immune surveillance in the nervous system and become activated in response to injury, showing increases in antigens found on macrophages, e.g. CD4 and MHCs. We investigated in adult rats the effects of a 2-week intraventricular infusion with ciliary neurotrophic factor (CNTF), a nervous system-associated ...
T, Hagg, S, Varon, J C, Louis
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Distribution of the 75-kD Low-Affinity Nerve Growth Factor Receptor in the Primate Peripheral Nervous System

Somatosensory & Motor Research, 1993
Disruption of the 75-kD low-affinity nerve growth factor (NGF) receptor (p75) has been shown to result in sensory and sympathetic nervous system deficits (Lee et al., 1992a,b). In order to establish precisely which subsets of neurons are capable of responding to neurotrophins (NTs) through the low-affinity NGF receptor, p75 was localized in the primate
G C, Schatteman   +3 more
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Age-dependent changes in gp75LNGFR (low-affinity nerve growth factor receptor) immunoreactivity in the rat cerebellar cortex

Neuroscience Letters, 1994
The expression of gp75LNGFR (low-affinity receptor of the nerve growth factor (NGF) family of neurotrophins) immunoreactivity was studied in the cerebellar cortex of male Wistar rats of 3 months (young), 12 months (adult) and 24 months of age using immunohistochemical techniques and a monoclonal antibody against rat-gp75LNGFR.
Vega JA   +3 more
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Dendritic reticulum cell immunoreactivity for low-affinity nerve growth factor receptor in malignant lymphomas.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 1997
Specimens of lymphoid and splenic tissue with reactive changes or involvement by non-Hodgkin's lymphomas or Hodgkin's disease were examined for low-affinity nerve growth factor receptor (NGFR) immunoreactivity of dendritic reticulum cells (DRCs) in frozen tissue and paraffin sections.
D M, Dorfman, A, Shahsafaei
openaire   +1 more source

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