Results 31 to 40 of about 91,338 (326)
ProNGF-p75NTR axis plays a proinflammatory role in inflamed joints. A novel pathogenic mechanism in chronic arthritis [PDF]
, 2017 To identify the role of mature nerve growth factor (mNGF), its immature form proNGF and their receptors in arthritis ...
Benedetti, Fabrizio De +9 more
core +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021 Background Brain‐derived neurotrophic factor (BDNF) is expressed in neuronal and nonneuronal cells and may affect vascular functions via its receptor, tropomyosin‐related kinase B (TrkB).
Sarah Zierold +7 more
doaj +1 more source
Expression of NGF, Trka and p75 in human cartilage
European Journal of Histochemistry, 2009 Nerve growth factor (NGF) exerts its action through two types of receptor: high-affinity tyrosine kinase A receptor (trkA) and low-affinity p75 receptor.
A Gigante +5 more
doaj +1 more source
Involvement of ras p2I in Neurotrophin-induced Response of Sensory, but Not Sympathetic Neurons [PDF]
, 1993 Little is known about the signal transduction mechanisms involved in the response to neurotrophins and other neurotrophic factors in neurons, beyond the activation of the tyrosine kinase activity of the neurotrophin receptors belonging to the trk family.
Barde, Y. A. +4 more
core +3 more sources
Acta Dermato-Venereologica, 2019 Prurigo nodularis is a highly pruritic and hyperplastic chronic dermatosis with unknown pathogenesis. Many pruritogenic mediators, including nerve growth factor, interleukin (IL)-31, thymic stromal lymphopoietin, and endothelin-1, are implicated in ...
Weilong Zhong +9 more
doaj +1 more source
Neurotrophins and Neuropathic Pain: Role in Pathobiology
Molecules, 2015 Neurotrophins (NTs) belong to a family of trophic factors that regulate the survival, growth and programmed cell death of neurons. In mammals, there are four structurally and functionally related NT proteins, viz. nerve growth factor (NGF), brain-derived
Nemat Khan, Maree T. Smith
doaj +1 more source
Interaction of lyssaviruses with the low-affinity nerve-growth factor receptor p75NTR
Journal of General Virology, 2001 The low-affinity nerve-growth factor receptor p75NTRinteractsin vitrowith the rabies virus (RV) glycoprotein and serves as a receptor for RV. TheLyssavirusgenus comprises seven genotypes (GTs) of rabies and rabies-related viruses. The ability of p75NTRto interact with the glycoprotein of representative lyssaviruses from each GT was investigated.
Tuffereau, Christine +6 more
openaire +2 more sources
The binding of botulinum neurotoxins to different peripheral neurons [PDF]
, 2017 Botulinum neurotoxins are the most potent toxins known. The double receptor binding modality represents one of the most significant properties of botulinum neurotoxins and largely accounts for their incredible potency and lethality.
Rossetto, O.
core +1 more source
VEGF189 binds NRP1 and is sufficient for VEGF/NRP1-dependent neuronal patterning in the developing brain [PDF]
, 2015 © 2015. Published by The Company of Biologists Ltd. This research was funded by a Wellcome Trust PhD fellowship to M.T. [092839/Z/10/Z] and a BBSRC project grant to C.R. and L.E. [BB/J00930X/1].
Cariboni, Anna +6 more
core +2 more sources
Polysialylation of NCAM characterizes the proliferation period of contractile elements during postnatal development of the epididymis. [PDF]
PLoS ONE, 2015 Polysialic acid (polySia) attached to the neural cell adhesion molecule (NCAM) regulates inter alia the proliferation and differentiation via the interactions with neurotrophins.
Peter Simon +5 more
doaj +1 more source